Paediatric Rheumatology and Related Disciplines
Juvenile idiopathic arthritis
Juvenile idiopathic arthritis (JIA) is arthritis of unknown cause beginning before age 16 and lasting at least six weeks. Subtypes matter for exams:
- Oligoarticular: fewer than five joints, often knee or ankle; high risk of chronic uveitis, especially with positive ANA - requires regular slit-lamp screening even when the eyes look and feel normal.
- Polyarticular: five or more joints; rheumatoid factor positive disease behaves like adult rheumatoid arthritis.
- Systemic: quotidian fevers, evanescent rash, serositis, very high inflammatory markers; watch for macrophage activation syndrome.
- Enthesitis-related and psoriatic: enthesitis, HLA-B27, axial involvement, psoriasis or nail changes.
Other paediatric conditions
- Kawasaki disease: fever for five or more days plus conjunctivitis, mucosal changes, rash, extremity changes and cervical lymphadenopathy; risk of coronary aneurysms, so treat with intravenous immunoglobulin and aspirin.
- Henoch-Schönlein (IgA) vasculitis: palpable purpura on the legs, abdominal pain, arthritis and nephritis.
- Growing pains: bilateral, evening, relieved by massage, no morning restriction.
- Septic arthritis and osteomyelitis: a child with a hot joint, fever and reluctance to move needs urgent aspiration and antibiotics.
- Chronic musculoskeletal pain and hypermobility: assess function and reassure appropriately without missing inflammatory disease.
Traps
- A child with a limp or refusing to walk must have infection and malignancy excluded.
- Normal inflammatory markers do not exclude uveitis; screening is scheduled by subtype and ANA status.
- Fevers that are quotidian and accompanied by a rash suggest systemic JIA rather than infection.
Rule of thumb
In a child with joint swelling, look at the eyes and ask about fevers - uveitis and systemic disease are the complications questions target.