Neonatal Resuscitation Program (NRP) study materials
Neonatal Resuscitation Program (NRP) study resources

Neonatal Resuscitation Program (NRP): Special Situations and NICU Resuscitation

Neonatal Resuscitation Program (NRP) · Work through your exam, one topic at a time.

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Special Situations and NICU Resuscitation

Situations that rewrite the algorithm

Meconium-stained fluid: no routine intubation or tracheal suctioning - begin with the standard algorithm, suction the mouth and nose only if obstructing.

Preterm (<35 weeks): start blended oxygen at 21–30%, use a T-piece for consistent PIP/PEEP, and protect temperature with a plastic wrap, hat, thermal mattress, and warm room.

Congenital diaphragmatic hernia: avoid mask ventilation (it distends bowel and worsens lung compression) - intubate early and place a nasogastric tube for decompression.

Suspected pneumothorax: sudden deterioration or asymmetric chest with poor response to PPV - consider transillumination and needle aspiration in the second intercostal space.

Airway anomalies, hydrops, neuromuscular disease, opioid exposure: anticipate difficulty; opioid-induced respiratory depression is treated with ventilation, not naloxone.

NICU/transport: infants may need sedation for agitation on a ventilator, careful fluid and pressor management, and continuation of cooling during transfer.

Traps

Suctioning every meconium infant; bag-masking a suspected CDH; delaying intubation for a known airway anomaly until the infant is bradycardic; forgetting the nasogastric tube; using naloxone in the delivery room.

Rule of thumb

Know the anomaly before the delivery, and change only what the anomaly demands. Worked example: antenatally diagnosed left CDH at 38 weeks - intubate at birth, avoid mask ventilation, decompress the stomach, and ventilate gently to avoid injuring the hypoplastic lung.