PSB HOAE study materials
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PSB HOAE: Natural Sciences

PSB HOAE · Work through your exam, one topic at a time.

All guide sections

Natural Sciences

Natural Sciences

The natural sciences subtest samples biology, chemistry, physics, and basic anatomy/physiology, with health-related applications. High-yield topics include cell transport, homeostasis, body systems, atoms and bonds, acids and bases, energy, and motion.

Core rules

  • Cell transport: diffusion moves solutes from high to low concentration; osmosis moves water across a membrane toward the side with more solute.
  • Homeostasis: negative feedback reverses a change; positive feedback amplifies it.
  • Body systems: arteries carry blood away from the heart; veins return blood; capillaries exchange materials.
  • Chemistry: pH below 7 is acidic, above 7 is basic; each whole pH step is a tenfold change in hydrogen ion concentration.
  • Physics: speed = distance ÷ time; force = mass × acceleration; energy is conserved but can change form.

Worked example

A red blood cell is placed in a hypertonic solution. The solution has a higher solute concentration than the cell. Water moves by osmosis from the cell, where water is more abundant, to the solution. The cell shrinks. A common wrong answer says the cell swells because “water follows salt” into the cell; in hypertonic conditions, the external solution already has more solute, so water leaves.

Traps

Reversing osmosis; confusing mitosis with meiosis; assuming all arteries carry oxygenated blood (the pulmonary artery does not); and treating pH as a linear scale.