ABEM ACCM flashcards
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- STEMI reperfusion time goals
- Primary PCI should be performed within 90 minutes of first medical contact at a PCI-capable center; fibrinolysis should begin within 30 minutes when PCI is unavailable and symptoms started under 12 hours.
- Cardiac tamponade decompensation trigger
- Positive-pressure ventilation and intubation can precipitate cardiovascular collapse in tamponade because increased intrathoracic pressure further impairs right ventricular filling; drainage should precede or accompany induction when feasible.
- Aortic dissection pressure target
- In acute aortic dissection, intravenous beta-blockade slows heart rate to about 60 beats per minute before adding a vasodilator such as nicardipine, targeting systolic pressure near 100 to 120 mmHg.
- High-risk pulmonary embolism treatment
- Pulmonary embolism with hypotension or shock warrants systemic thrombolysis, catheter-directed therapy, or surgical embolectomy; anticoagulation alone is insufficient because right ventricular failure drives mortality.
- ARDS lung-protective ventilation
- Ventilate with tidal volumes of 6 mL/kg predicted body weight and target plateau pressure below 30 cm H2O, allowing permissive hypercapnia; higher PEEP may be added for refractory hypoxemia.
- Tension pneumothorax decompression sites
- Needle decompression is performed at the second intercostal space midclavicular line or the fifth intercostal space anterior axillary line, followed by tube thoracostomy; treatment must not await radiographic confirmation.
- Light criteria exudate
- Pleural fluid is exudative when the protein ratio exceeds 0.5, the LDH ratio exceeds 0.6, or fluid LDH exceeds two-thirds the upper limit of normal serum LDH.
- Spontaneous bacterial peritonitis threshold
- Ascitic fluid polymorphonuclear count of 250 cells per microliter or greater establishes spontaneous bacterial peritonitis; start cefotaxime and add albumin for renal impairment or bilirubin above 4.
- Acute variceal hemorrhage bundle
- Give octreotide bolus then infusion plus prophylactic ceftriaxone, resuscitate to a restrictive hemoglobin target near 7 g/dL, and arrange endoscopic band ligation within 12 hours.
- Mesenteric ischemia imaging choice
- Acute mesenteric ischemia presents with pain out of proportion to examination; CT angiography of the abdomen and pelvis is the diagnostic study of choice, followed by heparin and urgent revascularization.
- Status epilepticus escalation sequence
- Give a benzodiazepine first, then a second-line agent such as levetiracetam, fosphenytoin, or valproate; refractory status requires intubation and continuous propofol, midazolam, or pentobarbital infusion.
- Thrombolysis blood pressure limits
- Before alteplase for ischemic stroke, blood pressure must be below 185/110 mmHg; after administration keep it below 180/105 for 24 hours using labetalol or nicardipine.
- Apnea test carbon dioxide target
- In brain death determination, disconnect from the ventilator after preoxygenation while monitoring for respiratory effort; a rise in arterial carbon dioxide above 60 mmHg with no breathing supports the diagnosis.
- Tranexamic acid in trauma
- Give 1 gram of tranexamic acid intravenously over 10 minutes followed by 1 gram over 8 hours, ideally within 3 hours of injury, for trauma patients with significant bleeding.
- Permissive hypotension exclusions
- Target systolic pressure near 80 to 90 mmHg until hemorrhage control, but maintain higher pressure in traumatic brain injury and pregnancy; excessive crystalloid worsens coagulopathy and hypothermia.
- Parkland burn formula
- Estimate 2 to 4 mL per kg body weight per percent total body surface area of lactated Ringer solution in the first 24 hours, giving half in the first 8 hours from burn time.
- Perimortem cesarean timing
- In maternal cardiac arrest, begin cesarean delivery within 4 minutes of arrest and complete by 5 minutes to improve maternal hemodynamics and fetal survival when resuscitation is unsuccessful.
- Acetaminophen toxicity antidote
- N-acetylcysteine is most effective when started within 8 hours of ingestion; risk is stratified using the Rumack-Matthew nomogram applied to a level drawn 4 or more hours after ingestion.
- Tricyclic overdose wide QRS
- Sodium bicarbonate 1 to 2 mEq/kg treats tricyclic-induced sodium channel blockade when QRS exceeds 100 ms or arrhythmia or hypotension appears; avoid class IA and IC antiarrhythmics.
- Lipid emulsion dosing
- For local anesthetic systemic toxicity, give 20 percent lipid emulsion 1.5 mL/kg as a bolus followed by infusion of 0.25 mL/kg/min; repeat the bolus if circulation does not improve.
- Heat stroke cooling
- Exertional heat stroke with core temperature above 40 Celsius and central nervous dysfunction requires immediate cold water immersion; antipyretics are ineffective because the hypothalamic set point is normal.
- High-altitude cerebral edema treatment
- Give dexamethasone 8 mg then 4 mg every 6 hours and descend immediately; supplemental oxygen and a portable hyperbaric chamber are temporizing measures when descent is delayed.
- Drowning resuscitation priority
- Hypoxia is the primary insult in drowning, so begin rescue breathing and CPR promptly; routine cervical spine immobilization and attempts to drain aspirated water are not indicated.
- Compartment syndrome delta pressure
- Delta pressure, diastolic blood pressure minus compartment pressure, below 30 mmHg with compatible symptoms justifies fasciotomy; palpable pulses are typically preserved until late in the course.
- Necrotizing fasciitis treatment
- Immediate surgical debridement plus broad-spectrum antibiotics including clindamycin for toxin suppression; imaging should not delay surgery when clinical suspicion is high.
- Open fracture antibiotics
- Administer prophylactic antibiotics within 1 hour of an open fracture, provide tetanus prophylaxis, and proceed to irrigation and debridement; avoid probing the wound in the emergency department.
- Septic shock initial bundle
- Measure lactate, obtain cultures, give broad-spectrum antibiotics within 1 hour, and infuse 30 mL/kg crystalloid; start norepinephrine for persistent hypotension with a mean arterial pressure target of 65 mmHg.
- Anaphylaxis epinephrine dose
- Intramuscular epinephrine 0.3 to 0.5 mg of the 1 mg/mL concentration into the lateral thigh, repeated every 5 to 15 minutes, is first-line therapy; antihistamines and steroids are adjuncts only.
- ACE inhibitor angioedema mechanism
- ACE inhibitor angioedema is bradykinin mediated and responds poorly to epinephrine; treat airway compromise with fresh frozen plasma, icatibant, or C1 esterase inhibitor concentrate.
- Hyperkalemia membrane stabilization
- Give intravenous calcium gluconate or chloride for ECG changes, then shift potassium intracellularly with insulin plus glucose and nebulized albuterol; dialysis removes total body potassium.
- DKA potassium replacement rule
- Total body potassium is depleted in diabetic ketoacidosis; begin replacement once serum potassium is below 5.2 mEq/L and renal output is adequate, and add dextrose when glucose nears 200 mg/dL.
- Thrombotic thrombocytopenic purpura treatment
- Thrombotic thrombocytopenic purpura is a hematologic emergency treated with urgent plasma exchange; platelet transfusion is avoided unless bleeding is life-threatening because it can worsen microvascular thrombosis.