ABIM Med Oncology case studies
ABIM Med Oncology · Put your knowledge to work in context.
The American Board of Internal Medicine (ABIM) Medical Oncology Certification Examination is the assessment physicians complete to earn board certification in medical oncology, typically after finishing an accredited hematology/oncology fellowship. It is aimed at internists who have trained in the diagnosis and management of solid tumors and hematologic malignancies and who want to demonstrate competence to patients, hospitals, and credentialing bodies. The ABIM Med Oncology case studies are 5 cases and about 2,708 words.
1A 62-year-old woman with HR-positive, HER2-negative metastatic breast cancer and progressive disease on palbociclib plus letrozole
A 62-year-old postmenopausal woman has hormone receptor-positive, HER2-negative metastatic breast cancer with bone and liver metastases. She received palbociclib plus letrozole for 14 months, then had radiographic progression in the liver.
695 words, about 3 min2A 58-year-old man with stage IV NSCLC and a ROS1 fusion who develops dyspnea on crizotinib
A 58-year-old man with a 30-pack-year smoking history presents with stage IV lung adenocarcinoma, with a malignant pleural effusion and a 2.5-cm right lower lobe mass. Molecular testing shows a ROS1 fusion and no EGFR, ALK, BRAF, KRAS, or MET alterations; PD-L1 tumor proportion score is 0%.
497 words, about 2 min3A 66-year-old man with metastatic pancreatic adenocarcinoma and a new portal vein thrombosis
A 66-year-old man has metastatic pancreatic ductal adenocarcinoma with liver metastases, diagnosed 3 months ago. He completed 4 cycles of FOLFIRINOX with partial response but has significant grade 2 peripheral neuropathy and fatigue.
543 words, about 3 min4A 70-year-old man with metastatic castration-resistant prostate cancer and new bone pain after docetaxel
A 70-year-old man has metastatic castration-resistant prostate cancer with bone metastases and a rising PSA (from 12 to 48 ng/mL over 3 months) despite androgen deprivation therapy with leuprolide. He completed 6 cycles of docetaxel 6 months ago with an initial PSA response, but now has new lower back pain and a PSA of 48 ng/mL.
514 words, about 3 min5A 45-year-old woman with newly diagnosed AML and a FLT3-ITD mutation who develops differentiation syndrome
A 45-year-old woman is diagnosed with acute myeloid leukemia. Cytogenetics show a normal karyotype, and molecular testing shows a FLT3-ITD mutation with a high allelic ratio, NPM1 mutation, and no IDH1/2 or TP53 mutations.
459 words, about 2 min