ABP Pediatric Gastroenterology flashcards
ABP Pediatric Gastroenterology · Build recall with a focused review session.
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- Rome IV constipation criteria
- For children, requires ≥2 of: ≤2 defecations/week, fecal incontinence, retentive posturing, painful stools, large fecal mass, large-diameter stools for ≥1 month.
- Celiac disease diagnosis
- IgA tTG >10× ULN with symptoms may allow diagnosis without biopsy; otherwise duodenal biopsy showing villous atrophy and crypt hyperplasia is required.
- Acute pancreatitis criteria
- Requires ≥2 of: abdominal pain, lipase >3× ULN, or imaging findings; lipase is preferred over amylase in children.
- Hirschsprung disease diagnosis
- Rectal biopsy showing absence of ganglion cells; presents with delayed meconium, distension, and bilious vomiting.
- Eosinophilic esophagitis criteria
- ≥15 eosinophils/hpf on esophageal biopsy with symptoms of dysphagia or food impaction; associated with atopy.
- Intussusception treatment
- Air or contrast enema is both diagnostic and therapeutic; ultrasound shows target sign; surgery if enema fails or perforation.
- Mid-parental height formula
- Boys: (father + mother + 13 cm)/2; girls: (father + mother − 13 cm)/2; target range ±8.5 cm.
- Failure to thrive definition
- Weight-for-age <5th percentile or crossing ≥2 major percentile lines downward on growth chart.
- Pyloric stenosis findings
- Nonbilious projectile vomiting at 3–6 weeks, olive mass, hypochloremic hypokalemic metabolic alkalosis; ultrasound shows pyloric thickness ≥3 mm and length ≥15 mm.
- H. pylori diagnosis
- Urea breath test or stool antigen test; avoid serology in children; treat with PPI + amoxicillin + clarithromycin or metronidazole for 14 days.
- Achalasia manometry
- Absent esophageal peristalsis and failure of lower esophageal sphincter relaxation; barium swallow shows bird-beak.
- Short bowel syndrome
- Resection leaving <25% of expected small bowel length; management includes parenteral nutrition, enteral feeding, and medications to reduce secretions.
- Lactose intolerance test
- Breath hydrogen test showing rise >20 ppm after lactose load; treat with lactose avoidance or lactase supplements.
- Fecal elastase
- <200 µg/g suggests exocrine pancreatic insufficiency; used in chronic pancreatitis and cystic fibrosis.
- Biliary atresia treatment
- Kasai portoenterostomy before 60 days improves outcomes; jaundice beyond 2 weeks with direct hyperbilirubinemia and acholic stools warrants urgent evaluation.
- Neonatal cholestasis definition
- Conjugated bilirubin >1 mg/dL if total <5 mg/dL, or >20% of total; evaluate for biliary atresia, metabolic, infectious, and genetic causes.
- Acute liver failure criteria
- Coagulopathy (INR ≥1.5) with encephalopathy or INR ≥2.0 with or without encephalopathy; no chronic liver disease.
- Wilson disease treatment
- Chelators (penicillamine, trientine) and zinc; diagnosis with low ceruloplasmin, elevated urinary copper, Kayser-Fleischer rings.
- Autoimmune hepatitis treatment
- Prednisone and azathioprine; elevated transaminases, hypergammaglobulinemia, autoantibodies (ANA, anti-smooth muscle).
- VEO-IBD genetic testing
- Onset <6 years; consider IL-10 receptor mutations and other monogenic causes; genetic testing recommended.
- FPIES management
- Food protein-induced enterocolitis syndrome: repetitive vomiting 1–3 hours after ingestion, diarrhea, lethargy; treat with IV fluids and avoidance of trigger.
- Upper endoscopy indications
- Dysphagia, persistent vomiting, GI bleeding, suspected celiac disease, foreign body; contraindications include hemodynamic instability and suspected perforation.
- Liver biopsy contraindications
- Coagulopathy (INR >1.5) and thrombocytopenia (<50,000); percutaneous or transjugular approach.
- Capsule endoscopy contraindication
- Suspected obstruction or stricture; used for small bowel evaluation.
- Informed consent elements
- Must include risks, benefits, alternatives; assent from minors when appropriate; parental permission required.
- GRADE system
- Rates quality of evidence and strength of recommendations; used in evidence-based medicine.
- PDSA cycle
- Plan-Do-Study-Act; used in quality improvement to test changes and measure outcomes.
- EER for infants
- 0–6 months: 108 kcal/kg/day; 7–12 months: 98 kcal/kg/day.
- BMI percentile categories
- Underweight <5th, normal 5th–<85th, overweight 85th–<95th, obese ≥95th.
- Gastroparesis diagnosis
- Delayed gastric emptying without obstruction; gastric emptying scintigraphy showing retention >60% at 2h or >10% at 4h.
- Choledochal cyst treatment
- Excision and Roux-en-Y hepaticojejunostomy; risk of cholangiocarcinoma; presents with pain, jaundice, mass.
- Post-transplant immunosuppression
- Tacrolimus or cyclosporine; monitor levels; complications include rejection, infection, EBV-related PTLD.