ABPath Anatomic Pathology study materials
ABPath Anatomic Pathology study resources

ABPath Anatomic Pathology study plan

ABPath Anatomic Pathology · Give each week a clear focus.

8 weeks · About 7 hours per week

Week 1

Surgical Pathology

  • Build a one-page morphologic algorithm for the five highest-yield carcinoma differentials (lung, breast, colon, prostate, thyroid) and annotate each branch with the single feature that separates the entities.

  • Classify 60 surgical unknowns by organ system, assign a grade or stage where applicable, and score each diagnosis against a written checklist.

  • Distinguish benign mimics from malignancy in 30 breast and 30 prostate cases, recording for each the one architectural or cytologic feature that changed the call.

  • Write 40 frozen-section-style provisional diagnoses, holding each to a two-minute time limit.

Your checkpoint

A 60-case organ-system log with self-scored diagnostic accuracy of at least 80% plus a written list naming every missed diagnosis and its root cause.

Week 2

Surgical Pathology & Ancillary Techniques (Immunohistochemistry, Electron Microscopy, Molecular Pathology)

  • Construct first-line immunohistochemical panels for 12 common differentials and justify each add-on stain in one sentence.

  • Compare cytokeratin, neuroendocrine, mesenchymal, and lymphoid marker profiles across 25 entities in a tabular format.

  • Evaluate common IHC pitfalls (aberrant expression, clone variability, antigen retrieval) using 20 deliberately ambiguous cases.

  • Interpret 15 cases where morphology and immunophenotype conflict, and state which result takes precedence and why.

Your checkpoint

A 25-case IHC panel worksheet with first-line panel, add-on stains, and documented rationale for each, scored at 80% or better against a written answer key.

Week 3

Cytopathology

  • Apply Bethesda 2014 cytologic criteria and management recommendations to 50 Pap test cases spanning all categories.

  • Apply the Milan System to 20 salivary gland aspirates and the Bethesda thyroid system to 20 thyroid aspirates.

  • Distinguish reactive from malignant populations in 40 body fluid and washings specimens, documenting the discriminating criteria.

  • Write 30 concise cytology reports that pair a category with an explicit follow-up recommendation.

Your checkpoint

A 50-case Pap classification set with exact Bethesda category, HPV/management recommendation, and concordance of 85% or better with the key.

Week 4

Cytopathology & Surgical Pathology

  • Re-sort the errors logged in weeks 1 through 3 into recurring morphologic themes and write a corrective rule for each theme.

  • Complete two 50-question timed mixed blocks in surgical pathology and cytopathology under exam pacing.

  • Compare cytologic and histologic appearances of the same 15 lesions to reinforce correlation between the two domains.

  • Identify the 10 entities you most often misclassify and build a one-page personal pitfall sheet.

Your checkpoint

A 100-question timed mixed Domain 1 and Domain 2 examination scored at 75% or better, plus a 15-item recurring-pitfall list with corrective rules.

Week 5

Ancillary Techniques (Immunohistochemistry, Electron Microscopy, Molecular Pathology)

  • Build a reference table of 25 clinically actionable molecular alterations, listing tumor type, optimal specimen, assay type, and therapeutic or prognostic implication.

  • Differentiate germline from somatic testing indications and specify when each is appropriate across 15 scenarios.

  • Evaluate the strengths and limits of electron microscopy in 10 diagnoses where it remains decisive (e.g., renal, neuromuscular, ciliary).

  • Interpret 20 molecular and ancillary result vignettes and translate each into a reportable line.

Your checkpoint

A completed 25-row molecular reference table plus a 20-question ancillary techniques self-test scored at 80% or better.

Week 6

Autopsy Pathology

  • Construct cause-of-death chains in the correct sequential format for 10 autopsy scenarios, separating immediate, intermediate, and underlying causes.

  • Describe the dissection sequence and sampling approach for heart, lung, brain, and abdominal viscera in a written protocol.

  • Classify the mechanisms of sudden cardiac, maternal, and pediatric deaths and match each to required ancillary studies.

  • Draft complete mock autopsy reports that satisfy documentation, clinicopathologic correlation, and communication standards.

Your checkpoint

Five complete mock autopsy reports with properly sequenced cause-of-death statements, self-graded against a written format and adequacy checklist.

Week 7

Laboratory Management and Informatics

  • Outline a laboratory-developed test validation plan covering accuracy, precision, analytic sensitivity, reference range, and specimen stability.

  • Interpret proficiency testing failures and draft a root-cause analysis with a corrective and preventive action plan.

  • Compare accreditation requirements for tissue handling, turnaround time, and quality metrics, and map each to a documentation artifact.

  • Evaluate informatics scenarios including result interfaces, synoptic reporting, and digital image retention policies.

Your checkpoint

A one-page LDT validation protocol plus written responses to 10 management vignettes, each citing the governing requirement.

Week 8

Surgical Pathology & Cytopathology & Autopsy Pathology & Ancillary Techniques (Immunohistochemistry, Electron Microscopy, Molecular Pathology) & Laboratory Management and Informatics

  • Complete two full-length timed mixed examinations under strict exam conditions and score them by domain.

  • Re-drill the 40 highest-frequency errors from the week 1 through week 7 error log until each is answered correctly twice consecutively.

  • Recite from memory the diagnostic criteria for the 20 entities most often tested across all five domains.

  • Consolidate all personal pitfall sheets into a single final-review document organized by domain.

Your checkpoint

Two 150-question timed mixed examinations scored at 70% or better with an error log containing no more than 10 unresolved items.

Milestones

Week 2: Surgical pathology accuracy at 80% or better on the 60-case log, with a working IHC decision framework that correctly selects first-line panels in at least 20 of 25 cases.

Week 4: Mixed Domain 1 and Domain 2 timed block at 75% or better, with every error assigned to a named morphologic theme rather than left unclassified.

Week 6: Ancillary techniques self-test at 80% or better and five autopsy reports that pass the cause-of-death format checklist without revision.

Week 8: Both full-length mixed examinations at 70% or better, no domain below 65%, and a final consolidated pitfall document covering all five domains.