ABPath Cytopathology study materials
ABPath Cytopathology study resources

ABPath Cytopathology study guide

ABPath Cytopathology · Work through your exam, one topic at a time.

The ABPath Cytopathology subspecialty examination is a one-day, computer-based certifying exam offered by the American Board of Pathology for pathologists who have completed cytopathology fellowship training and wish to demonstrate subspecialty competence. It combines Written/Practical sections with Virtual Microscopy sections; there are no glass slides. All items are multiple-choice, single-best-answer, and are designed to test body of knowledge, judgment, and problem-solving rather than recall alone. The practical material emphasizes interpretive skills, clinical-radiologic-histologic correlation, and management guidelines, while the written material covers factual, administrative, technical, and regulatory content plus systems-based practice and patient care. Topics on this exam: Gynecologic/Anal Cytopathology, Non-Gynecologic and Fine Needle Aspiration Cytopathology, and Laboratory Management/Administration. The ABPath Cytopathology study guide has 3 sections and about 774 words.

01

Gynecologic and Anal Cytopathology

Bethesda System for Cervical Cytology : Understand categories (NILM, ASC-US, LSIL, ASC-H, HSIL, AGC, AIS, carcinoma) and their management implications. HPV Biology : Link HPV types (16, 18, 31, 33, etc.) to lesion severity; recognize HPV cytopathic effect (koilocytosis). Anal Cytology : Apply similar Bethesda terminology; know risk groups (HIV+, MSM) and sampling techniques. Glandular Lesions : Differentiate AGC subtypes (endocervical, endometrial, extrauterine) and AIS from invasive adenocarcinoma.

278 words, about 1 min
02

Non-Gynecologic and Fine Needle Aspiration Cytopathology

Thyroid FNA : Bethesda System for Reporting Thyroid Cytopathology (I–VI); understand risk of malignancy and management. Salivary Gland FNA : Milan System categories; differentiate pleomorphic adenoma, Warthin tumor, mucoepidermoid carcinoma. Lymph Node FNA : Recognize reactive hyperplasia, granulomas, lymphoma, metastatic carcinoma. Body Fluid Cytology : Distinguish reactive mesothelial cells from adenocarcinoma; use ancillary tests (immunocytochemistry).

250 words, about 1 min
03

Laboratory Management and Administration

Regulatory Compliance : CLIA '88, CAP accreditation, proficiency testing, quality control. Quality Assurance : Documented SOPs, equipment maintenance, competency assessment. Safety : OSHA bloodborne pathogens standard, chemical hygiene, ergonomics. Billing and Coding : CPT codes for cytopathology (e.g., 88142, 88175), ICD-10 coding, reimbursement.

246 words, about 1 min