ABPN Geriatric Psychiatry study materials
ABPN Geriatric Psychiatry study resources

ABPN Geriatric Psychiatry key terms

ABPN Geriatric Psychiatry · Get comfortable with the vocabulary.

Pseudodementia

Cognitive impairment that mimics dementia but is caused mainly by depression; patients often answer 'I don't know,' show variable effort, and improve when mood is treated.

Related: Geriatric Depression Scale, Delirium
Delirium

Acute, fluctuating disturbance of attention and awareness, usually from a medical cause, medications, or withdrawal; it develops over hours to days and is frequently missed in older adults.

Related: Confusion Assessment Method, Anticholinergic Burden, Pseudodementia
Confusion Assessment Method (CAM)

A brief structured screening tool for delirium requiring acute onset with fluctuation plus inattention, and either disorganized thinking or altered level of consciousness.

Related: Delirium
Mild Cognitive Impairment (MCI)

Objective cognitive decline greater than expected for age that does not substantially impair daily function; it raises but does not guarantee the risk of progressing to dementia.

Related: Mini-Mental State Examination, Montreal Cognitive Assessment, Alzheimer Disease
Mini-Mental State Examination (MMSE)

A 30-point bedside test of orientation, registration, attention, recall, language, and construction; scores are adjusted for education and fall with age and sensory impairment.

Related: Montreal Cognitive Assessment, Mild Cognitive Impairment (MCI)
Montreal Cognitive Assessment (MoCA)

A 30-point screening instrument more sensitive than the MMSE to mild impairment, especially executive and visuospatial deficits; a score below 26 suggests cognitive impairment.

Related: Mini-Mental State Examination (MMSE), Mild Cognitive Impairment (MCI)
Alzheimer Disease

Progressive neurodegenerative dementia with insidious short-term memory loss and later language, visuospatial, and functional decline; it is the most common cause of dementia in late life.

Related: Cholinesterase Inhibitors, Mild Cognitive Impairment (MCI), Lewy Body Dementia
Lewy Body Dementia

Dementia with fluctuating cognition, recurrent well-formed visual hallucinations, parkinsonism, and sensitivity to antipsychotics; REM sleep behavior disorder often precedes diagnosis.

Related: Alzheimer Disease, Frontotemporal Dementia, Neuroleptic Sensitivity
Frontotemporal Dementia

Neurodegeneration of frontal and temporal lobes causing early personality change, disinhibition, or language deficits, with relative sparing of memory and visuospatial skills early on.

Related: Lewy Body Dementia, Primary Progressive Aphasia
Vascular Dementia

Cognitive impairment attributed to cerebrovascular disease, typically with stepwise decline, executive slowing, and focal neurologic findings; risk factors include hypertension, diabetes, and prior stroke.

Related: Alzheimer Disease, Cerebral Amyloid Angiopathy
Cholinesterase Inhibitors

Donepezil, rivastigmine, and galantamine, which raise synaptic acetylcholine and modestly slow symptom progression in Alzheimer disease; adverse effects include nausea, bradycardia, and diarrhea.

Related: Memantine, Alzheimer Disease
Memantine

An NMDA receptor antagonist used for moderate to severe Alzheimer disease, often added to a cholinesterase inhibitor; it is renally cleared and may cause dizziness or confusion.

Related: Cholinesterase Inhibitors, Alzheimer Disease
Neuroleptic Sensitivity

Severe rigidity, sedation, or worsening confusion after even small antipsychotic doses, classically seen in Lewy body dementia; it warrants avoiding or minimizing these drugs.

Related: Lewy Body Dementia, Tardive Dyskinesia
Geriatric Depression Scale (GDS)

A yes/no self-report screen for depression in older adults that omits somatic items; the 15-item short form scores 5 or more as suggestive of depression.

Related: Pseudodementia, Late-Life Depression
Late-Life Depression

Depressive illness arising after age 60, often with prominent somatic complaints, apathy, cognitive slowing, and higher relapse risk; it is associated with vascular disease and suicide risk.

Related: Geriatric Depression Scale (GDS), Pseudodementia, Electroconvulsive Therapy
Electroconvulsive Therapy (ECT)

Induction of a controlled seizure under anesthesia to treat severe depression, catatonia, or psychosis; it is effective in older adults but requires attention to cardiac and cognitive effects.

Related: Late-Life Depression, Delirium
Serotonin Syndrome

A toxic reaction to serotonergic drugs causing agitation, tremor, clonus, hyperreflexia, fever, and autonomic instability; it can be fatal and requires stopping the offending agents.

Related: Anticholinergic Burden, Neuroleptic Malignant Syndrome
Neuroleptic Malignant Syndrome

A life-threatening reaction to dopamine-blocking drugs with rigidity, high fever, autonomic instability, and elevated creatine kinase; treatment includes stopping the drug and supportive care.

Related: Serotonin Syndrome, Tardive Dyskinesia
Tardive Dyskinesia

Involuntary repetitive movements, often of the mouth, tongue, or face, arising after prolonged dopamine-blocking treatment; older adults are at elevated risk and symptoms may persist.

Related: Neuroleptic Sensitivity, Neuroleptic Malignant Syndrome
Anticholinergic Burden

The cumulative effect of drugs blocking acetylcholine, which can cause confusion, constipation, urinary retention, dry mouth, and falls; it is a common reversible contributor to cognitive decline.

Related: Delirium, Serotonin Syndrome
Benzodiazepine Deprescribing

A gradual, planned dose reduction of benzodiazepines or related sedative-hypnotics to limit falls, confusion, and dependence; abrupt cessation risks withdrawal seizures.

Related: Anticholinergic Burden, Delirium
Beers Criteria

An expert consensus list of medications potentially inappropriate for older adults because of high risk of adverse effects, used to guide safer prescribing and medication review.

Related: Anticholinergic Burden, Benzodiazepine Deprescribing
Polypharmacy

Concurrent use of multiple medications, often defined as five or more; in older adults it raises risks of interactions, adverse effects, and hospitalization and warrants periodic review.

Related: Beers Criteria, Anticholinergic Burden
Capacity Assessment

Evaluation of a patient's ability to understand relevant information, appreciate consequences, reason about options, and communicate a choice for a specific decision.

Related: Advance Directive, Guardianship
Advance Directive

A written statement made while a person has capacity that records future treatment preferences or names a surrogate decision-maker for when the person can no longer decide.

Related: Capacity Assessment, Guardianship
Guardianship

A court-appointed arrangement in which a person or agency makes decisions for someone found unable to manage personal or financial affairs; it is the least restrictive alternative last.

Related: Capacity Assessment, Elder Abuse
Elder Abuse

Physical, emotional, sexual, or financial harm, neglect, or abandonment of an older adult, often by a caregiver or family member; clinicians are typically mandated to report suspected cases.

Related: Guardianship, Caregiver Burden
Caregiver Burden

The physical, emotional, and financial strain experienced by people caring for an impaired older adult; it predicts depression, institutionalization, and risk of mistreatment.

Related: Elder Abuse, Respite Care
Respite Care

Temporary relief for family caregivers through short-term professional or residential care of the patient, intended to reduce burden and sustain home caregiving.

Related: Caregiver Burden
Sundowning

Worsening of confusion, agitation, or disorientation in late afternoon or evening, common in dementia; contributors include fatigue, poor lighting, and disrupted routine.

Related: Delirium, Behavioral and Psychological Symptoms of Dementia
Behavioral and Psychological Symptoms of Dementia (BPSD)

Agitation, aggression, psychosis, mood changes, and other noncognitive symptoms of dementia; first-line management is nonpharmacologic, with medications reserved for severe or dangerous symptoms.

Related: Sundowning, Neuroleptic Sensitivity
Apathy

Reduced motivation and goal-directed behavior without distress, common in dementia and depression; it can be mistaken for depression but lacks prominent sadness or guilt.

Related: Late-Life Depression, Behavioral and Psychological Symptoms of Dementia (BPSD)
Suicide Risk in Older Adults

Elevated risk in late life, especially in older men, often associated with depression, chronic illness, isolation, and access to lethal means; intent may be communicated indirectly.

Related: Late-Life Depression, Capacity Assessment
Primary Progressive Aphasia

A neurodegenerative language disorder with gradual loss of word finding or comprehension while other cognitive domains remain relatively preserved early; it is a variant of frontotemporal degeneration.

Related: Frontotemporal Dementia
Cerebral Amyloid Angiopathy

Deposition of amyloid in small cerebral vessels that predisposes to lobar hemorrhages and cognitive decline; it is a concern when anticoagulating older patients with cognitive impairment.

Related: Vascular Dementia