ACLAM case studies
ACLAM · Put your knowledge to work in context.
ACLAM - the American College of Laboratory Animal Medicine - is a specialty board recognized by the American Veterinary Medical Association (AVMA) as the certifying organization for laboratory animal medicine, a recognized specialty within the veterinary medical profession. Its certification program is intended for veterinarians who specialize in the care and responsible use of laboratory animals, and it recognizes demonstrated expertise in animal resource management, clinical care, research collaboration, and education. The ACLAM case studies are 5 cases and about 2,376 words.
1Mouse Colony Genetic Drift and Breeding Scheme
You manage a specific-pathogen-free colony of C57BL/6J mice for a study on age-related hearing loss. The colony has been closed for 18 months, with 12 breeding pairs per generation and a generation interval of 3 months.
497 words, about 2 min2Postoperative Analgesia in a Rat Model of Bone Cancer
A researcher is using a rat model of bone cancer pain. Male Sprague-Dawley rats (n=40, 250-300g) undergo intratibial injection of MRMT-1 carcinoma cells into the right tibia.
498 words, about 2 min3Collaboration Conflict: Sharing Transgenic Mice
Your institution has a transgenic mouse line (B6.Cg-Tg(Thy1-YFP)HJrs/J) that expresses yellow fluorescent protein in neurons. The line is maintained under a Material Transfer Agreement (MTA) from the original developer, which restricts sharing with third parties without written consent.
468 words, about 2 min4Training Program for New Animal Care Staff
You are responsible for training new animal care technicians in a facility that houses mice, rats, and rabbits. The facility has a high turnover rate; in the past year, 5 of 10 technicians left within 6 months.
441 words, about 2 min5Unexpected Mortality in a Zebrafish Facility
In a zebrafish facility, the recirculating water system serves 5 racks with a total of 500 tanks. Water parameters are monitored daily: pH 7.2, conductivity 500 µS/cm, dissolved oxygen 6.5 mg/L, and temperature 28.5°C.
472 words, about 2 min