ACVN Veterinary Nutrition study materials
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Suspected Aflatoxin Exposure in a Multi-Cat Household

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Suspected Aflatoxin Exposure in a Multi-Cat Household

A client with four cats reports that one cat died suddenly and another is lethargic and jaundiced. All cats eat the same dry food from a recently opened bag stored in a humid garage. The owner asks whether the food is safe and whether to switch diets. The clinic has no toxicology results yet. The veterinarian asks you to advise on immediate steps and on how to interpret the situation.

1. What immediate advice should be given regarding the food and the remaining cats?

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Advise stopping the suspect food immediately and preserving the bag, lot number, and remaining food for testing. Feed a different complete diet from a different lot. Have all cats examined, with baseline liver enzymes, bilirubin, and coagulation testing, since aflatoxin can cause hepatic injury and coagulopathy. Report the suspected illness to the manufacturer and the appropriate regulatory authority. Do not rely on home remedies.

2. How would you interpret the situation before test results return?

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The combination of sudden death, jaundice, and a shared food source raises concern for aflatoxicosis or another contaminant, but other causes such as infectious disease or toxins in the home must be considered. Without toxicology, avoid definitive attribution. Explain the uncertainty to the owner, document findings, and coordinate with the manufacturer and regulators. If aflatoxin is confirmed, follow regulatory guidance on recall and monitoring.

3. What monitoring would you recommend for the surviving cats?

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Monitor appetite, mentation, and jaundice daily; recheck liver enzymes and coagulation times periodically. Supportive care includes fluids, antiemetics, and nutritional support if intake is poor. Advise the owner to watch for bleeding, which may indicate coagulopathy.