DHA GP Exam flashcards
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- Anion gap formula
- Sodium minus (chloride plus bicarbonate), normally 8–12 mEq/L. An elevated gap suggests methanol, uremia, diabetic ketoacidosis, or lactic acidosis.
- DKA diagnostic triad
- Hyperglycemia above 250 mg/dL, ketonemia or ketonuria, and anion-gap metabolic acidosis with pH below 7.30. Treatment is fluids, insulin infusion, and potassium replacement.
- Hyperkalemia ECG progression
- Peaked T waves appear first, followed by PR prolongation, widened QRS, and a sine wave. IV calcium is given immediately when ECG changes are present.
- STEMI reperfusion targets
- Primary PCI within 90 minutes of first medical contact is preferred; fibrinolysis within 30 minutes is the alternative when PCI is unavailable and symptoms are under 12 hours.
- Stroke thrombolysis window
- Intravenous alteplase may be given up to 4.5 hours from last known well. Thrombectomy is offered up to 24 hours in selected large-vessel occlusions with salvageable brain tissue.
- HFrEF quadruple therapy
- For ejection fraction 40% or less, combined ARNI or ACE inhibitor, beta-blocker, mineralocorticoid receptor antagonist, and SGLT2 inhibitor reduce mortality and hospitalization.
- Hyponatremia correction limit
- Serum sodium should rise no more than 8–10 mEq/L in 24 hours to avoid osmotic demyelination. Hypertonic saline is reserved for seizures or severe neurologic symptoms.
- Prediabetes HbA1c range
- An HbA1c of 5.7–6.4% defines prediabetes. Structured lifestyle intervention reduces progression to type 2 diabetes by roughly 58% over three years.
- Colorectal screening starting age
- Average-risk adults begin screening at 45 years and continue to 75. Colonoscopy every 10 years or annual fecal immunochemical testing are accepted strategies.
- Statin primary prevention threshold
- Adults aged 40–75 with at least one risk factor and a 10-year ASCVD risk of 10% or greater should receive a moderate-intensity statin.
- Acute otitis media first-line
- High-dose amoxicillin 80–90 mg/kg/day is first-line therapy. Observation for 48–72 hours is reasonable in children aged 2 years or older with nonsevere illness.
- Outpatient pneumonia antibiotic choice
- Without comorbidity, amoxicillin or doxycycline is used. With comorbidity, prescribe amoxicillin-clavulanate plus a macrolide, or a respiratory fluoroquinolone alone.
- Smoking cessation pharmacotherapy
- Varenicline, bupropion, or nicotine replacement combined with counseling is first-line. Combining nicotine patch with a short-acting form is more effective than a single product.
- Febrile neonate rule
- Any infant 28 days old or younger with temperature 38.0°C or higher needs a full sepsis evaluation and empirical antibiotics, regardless of how well the infant appears.
- Pediatric maintenance fluid rule
- Holliday-Segar 4-2-1 rule: 4 mL/kg/hour for the first 10 kg, 2 mL/kg/hour for the next 10 kg, and 1 mL/kg/hour for each kilogram above 20.
- Bronchiolitis supportive care
- Management is oxygen, hydration, and nasal suction. Routine bronchodilators, systemic corticosteroids, and antibiotics are not recommended for RSV bronchiolitis.
- Kawasaki disease criteria
- Fever for 5 days or more plus 4 of 5 features: conjunctivitis, oral changes, rash, extremity changes, cervical lymphadenopathy. Give IVIG and aspirin to prevent coronary aneurysms.
- Neonatal jaundice treatment threshold
- Phototherapy is started using hour-specific bilirubin nomograms by risk category. Exchange transfusion is indicated near threshold levels or with signs of acute bilirubin encephalopathy.
- Infant motor milestones
- Most infants sit without support by 8 months and walk independently by 12–15 months. Loss of previously achieved milestones requires developmental evaluation.
- Pediatric dehydration signs
- Reduced skin turgor, capillary refill over 2 seconds, sunken eyes, and decreased urine output indicate 5% or greater dehydration needing oral or intravenous rehydration.
- Preeclampsia diagnostic criteria
- Blood pressure 140/90 mmHg or higher after 20 weeks plus proteinuria or end-organ dysfunction. Magnesium sulfate prevents and treats eclamptic seizures.
- Gestational diabetes screening
- Screen at 24–28 weeks with a 50-g one-hour glucose challenge. A positive screen is followed by a 3-hour 100-g test using Carpenter-Coustan thresholds.
- Postpartum hemorrhage definition
- Blood loss of 1000 mL or more, or any loss causing hemodynamic instability, within 24 hours of birth. Uterine atony is the most common cause.
- Rh immune globulin timing
- Anti-D is given at 28 weeks and within 72 hours of delivering an Rh-positive infant, and also after amniocentesis, miscarriage, or antepartum bleeding.
- Ectopic pregnancy methotrexate criteria
- Methotrexate suits hemodynamically stable, unruptured ectopic pregnancy with hCG below 5000 mIU/mL, mass under 4 cm, and no fetal cardiac activity.
- Active phase labor progress
- The active first stage runs from 6 to 10 cm dilation, progressing at least 1 cm per hour in nulliparas; slower progress prompts evaluation for arrest.
- ATLS primary survey order
- Airway with cervical spine protection, breathing, circulation with hemorrhage control, disability, then exposure with prevention of hypothermia.
- Parkland burn formula
- Give 4 mL × weight in kg × percent total body surface area burned of lactated Ringer over 24 hours, with half infused in the first 8 hours after injury.
- Tension pneumothorax management
- Immediate needle decompression is followed by chest tube insertion. Treatment must not be delayed for imaging when clinical signs are present.
- Anaphylaxis first-line treatment
- Intramuscular epinephrine 0.3–0.5 mg of 1:1000 solution into the anterolateral thigh, repeated every 5–15 minutes as needed. Antihistamines and steroids are adjuncts only.
- Septic shock one-hour bundle
- Measure lactate, draw blood cultures, and give broad-spectrum antibiotics plus 30 mL/kg crystalloid within the first hour of recognizing septic shock.
- Appendicitis Alvarado score
- The score combines migratory pain, anorexia, nausea, right lower quadrant tenderness, rebound, fever, and leukocytosis; a score of 7 or more supports appendicitis.