Afghanistan Medical Exit Exam flashcards
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- Anion gap formula
- Anion gap equals serum sodium minus the sum of chloride and bicarbonate. Normal is about 8 to 12 mmol/L; a raised gap suggests unmeasured anions such as ketones, lactate, or toxins.
- Holliday-Segar maintenance fluids
- Daily maintenance fluid is 100 mL/kg for the first 10 kg, 50 mL/kg for the next 10 kg, and 20 mL/kg for each kilogram beyond 20, applied to pediatric patients.
- CURB-65 score
- Pneumonia severity score counting confusion, urea above 7 mmol/L, respiratory rate 30 or more, low blood pressure, and age 65 or older; higher scores predict mortality.
- Magnesium sulfate in eclampsia
- Magnesium sulfate is the preferred drug to prevent and treat seizures in preeclampsia and eclampsia; monitor reflexes, respiratory rate, and urine output for toxicity.
- Sensitivity and specificity
- Sensitivity is the proportion of true cases correctly identified; specificity is the proportion of non-cases correctly identified. Neither depends on disease prevalence in the population.
- Naloxone
- An opioid receptor antagonist that rapidly reverses opioid-induced respiratory depression and sedation. It is titrated intravenously to restore adequate spontaneous breathing without fully reversing analgesia.
- Herd immunity threshold
- The fraction of a population that must be immune to interrupt transmission, approximated as 1 minus 1 divided by the basic reproduction number R0.
- Tension pneumothorax management
- A clinical diagnosis with severe dyspnea, hypotension, and absent breath sounds; immediate needle decompression followed by tube thoracostomy is required without waiting for imaging.
- Cardiac output equation
- Cardiac output equals heart rate multiplied by stroke volume. Normal resting output is approximately five liters per minute and rises with metabolic demand.
- Informed consent elements
- Valid consent requires patient capacity, adequate disclosure of risks and alternatives, comprehension, and voluntary choice. It is an ongoing process rather than a single signature.
- Diabetic ketoacidosis treatment
- Manage with isotonic intravenous fluids, an insulin infusion, and potassium replacement once serum potassium is not elevated; monitor glucose, ketones, and electrolytes closely.
- ATLS primary survey
- A structured trauma assessment: airway with cervical spine protection, breathing, circulation with hemorrhage control, disability with neurologic check, and exposure with environmental control.
- Kawasaki disease criteria
- Fever for at least five days plus conjunctivitis, oral mucositis, rash, extremity changes, and cervical lymphadenopathy. Treatment with IVIG and aspirin prevents coronary artery aneurysms.
- Postpartum hemorrhage first steps
- Uterine atony is the commonest cause. Management includes uterine massage, oxytocin, additional uterotonics, tranexamic acid, and escalation to surgical or interventional measures.
- Warfarin and INR
- Warfarin inhibits vitamin K epoxide reductase, reducing synthesis of clotting factors. Effect is monitored with the INR, and vitamin K reverses excessive anticoagulation.
- Acute inflammation cells
- Neutrophils predominate in acute inflammation, whereas lymphocytes, plasma cells, and macrophages characterize chronic inflammation and many granulomatous diseases.
- Mean arterial pressure estimate
- Mean arterial pressure approximates diastolic pressure plus one third of the pulse pressure, reflecting the time-weighted average of arterial pressure across the cardiac cycle.
- Assessing decision-making capacity
- Clinicians assess whether the patient understands information, appreciates consequences, reasons about options, and communicates a choice. Competence is a separate legal determination.
- Anaphylaxis first-line treatment
- Intramuscular epinephrine into the anterolateral thigh is the immediate first-line therapy; antihistamines and corticosteroids are adjuncts and do not replace epinephrine.
- Appendicitis classic presentation
- Periumbilical pain migrating to the right lower quadrant with McBurney point tenderness, anorexia, nausea, and low-grade fever suggests acute appendicitis requiring surgical evaluation.
- Neonatal resuscitation heart rate
- Provide positive pressure ventilation when the newborn is apneic or heart rate is below 100 per minute; begin chest compressions if heart rate stays below 60 despite effective ventilation.
- Preeclampsia definition
- New hypertension after 20 weeks of gestation with proteinuria or evidence of end-organ dysfunction; delivery is the definitive treatment, with magnesium sulfate for seizure prophylaxis.
- Relative risk versus odds ratio
- Relative risk compares incidence between exposed and unexposed groups in cohort studies; the odds ratio is used in case-control studies and approximates relative risk when disease is rare.
- Aminoglycoside toxicity
- Aminoglycosides can cause nephrotoxicity and ototoxicity. Serum levels are monitored, and concurrent use of other nephrotoxic drugs should be avoided when possible.
- Coagulation test pathways
- Prothrombin time and INR assess the extrinsic and common pathways, while activated partial thromboplastin time assesses the intrinsic and common pathways of coagulation.
- Bohr effect
- Rising carbon dioxide, hydrogen ion concentration, and temperature shift the oxygen-hemoglobin dissociation curve to the right, reducing hemoglobin affinity and enhancing tissue oxygen delivery.
- Confidentiality limits
- Patient confidentiality may be breached only when legally required, such as mandatory reporting of certain communicable diseases or a serious threat to an identifiable person.
- Sepsis initial priorities
- Recognize infection with organ dysfunction, measure lactate, give broad-spectrum antibiotics and intravenous fluids promptly, and reassess perfusion and response to therapy.
- Nephrotic syndrome features
- Characterized by proteinuria above 3.5 grams per day, hypoalbuminemia, edema, and hyperlipidemia. In adults, kidney biopsy often guides the underlying cause.
- Bowel obstruction initial management
- Nil per os, intravenous fluid resuscitation, nasogastric decompression, analgesia, and serial abdominal examinations, with surgery for strangulation, perforation, or failure to resolve.
- Intussusception diagnosis and treatment
- Colicky abdominal pain with vomiting and currant-jelly stool in a young child; ultrasound shows a target sign, and an air or contrast enema is both diagnostic and therapeutic.
- Heparin monitoring and reversal
- Unfractionated heparin potentiates antithrombin and is monitored by activated partial thromboplastin time; protamine sulfate is the specific reversing agent for overdose.