ANCC AGPCNP-BC flashcards
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- Orthostatic hypotension criteria
- A fall in systolic blood pressure of at least 20 mm Hg, or diastolic of at least 10 mm Hg, within three minutes of standing or head-up tilt.
- Mini-Cog scoring
- A three-item recall plus clock drawing; a total score of 2 or less out of 5 suggests cognitive impairment and warrants further dementia evaluation.
- Timed Up and Go threshold
- A completion time longer than 12 seconds on the Timed Up and Go test indicates increased fall risk and prompts gait, balance, and medication review.
- Ankle-brachial index interpretation
- An ABI of 0.90 or less confirms peripheral artery disease, while values above 1.40 suggest noncompressible calcified vessels common in diabetes and kidney disease.
- AUDIT-C positive thresholds
- Scores of 4 or more in men and 3 or more in women indicate unhealthy alcohol use and warrant a fuller assessment such as the full AUDIT.
- PHQ-2 to PHQ-9
- A score of 3 or more on the two-item PHQ-2 triggers administration of the nine-item PHQ-9 to grade depression severity and guide treatment.
- Post-bronchodilator FEV1/FVC ratio
- A post-bronchodilator FEV1/FVC ratio below 0.70 confirms persistent airflow obstruction and establishes a diagnosis of COPD in a symptomatic adult.
- Delirium versus dementia
- Delirium has acute onset, fluctuating course, and inattention; dementia shows insidious progressive decline in memory or another cognitive domain with arousal preserved until late.
- Light's criteria
- Pleural fluid is an exudate if the protein ratio exceeds 0.5, the LDH ratio exceeds 0.6, or fluid LDH exceeds two-thirds the upper normal serum limit.
- Serum-ascites albumin gradient
- A gradient of 1.1 g/dL or more between serum and ascitic albumin indicates portal hypertension-related ascites; lower values suggest carcinomatosis, tuberculosis, or pancreatitis.
- Diabetes diagnostic A1c
- An A1c of 6.5 percent or higher, fasting glucose of 126 mg/dL or higher, or two-hour OGTT of 200 mg/dL or higher confirms diabetes; asymptomatic results require confirmation.
- Multiple myeloma CRAB features
- HyperCalcemia, Renal insufficiency, Anemia, and Bone lesions define the CRAB criteria that separate multiple myeloma from monoclonal gammopathy of undetermined significance.
- Positive likelihood ratio strength
- A positive likelihood ratio above 10 substantially raises disease probability, while a negative likelihood ratio below 0.1 substantially lowers it at the bedside.
- Hyponatremia initial step
- Measure serum osmolality first; a low value confirms true hypotonic hyponatremia, then check urine osmolality and urine sodium to classify the cause.
- High-intensity statin doses
- Atorvastatin 40 to 80 mg or rosuvastatin 20 to 40 mg daily lowers LDL cholesterol by 50 percent or more and is used for established atherosclerotic cardiovascular disease.
- Statin primary prevention threshold
- A 10-year ASCVD risk of 7.5 percent or higher by the Pooled Cohort Equations supports starting a moderate-intensity statin after clinician-patient risk discussion.
- A1c goals in older adults
- Target below 7 percent for most adults, but below 8 percent for those with limited life expectancy, frailty, extensive comorbidity, or high hypoglycemia risk.
- Recombinant zoster vaccine schedule
- Two doses of recombinant zoster vaccine are given two to six months apart for adults 50 and older, regardless of prior shingles or prior live vaccine.
- Colorectal cancer screening interval
- Average-risk adults begin screening at 45 and continue to 75; colonoscopy every 10 years and annual FIT are accepted primary strategies.
- Aspirin primary prevention restriction
- Aspirin is not initiated routinely for primary prevention in adults 60 and older because bleeding risk offsets modest benefit; decisions are individualized.
- Start low go slow
- Begin older adults at roughly half the usual adult dose and titrate gradually, because reduced hepatic and renal clearance increases drug accumulation and adverse effects.
- Cockcroft-Gault creatinine clearance
- Creatinine clearance equals (140 minus age) times weight in kg, divided by 72 times serum creatinine, multiplied by 0.85 for women; used for renal dose adjustment.
- Basal insulin starting dose
- Start basal insulin at 10 units daily or 0.1 to 0.2 units per kg daily, titrating by fasting glucose every three days while monitoring for hypoglycemia.
- CHA2DS2-VASc anticoagulation threshold
- Anticoagulation is recommended for atrial fibrillation when the score is at least 2 in men or 3 in women, and may be considered at 1 in men.
- Five A's tobacco cessation
- Ask, Advise, Assess, Assist, and Arrange follow-up; combine with pharmacotherapy such as varenicline, bupropion, or nicotine replacement to improve quit rates.
- Naloxone co-prescribing trigger
- Offer naloxone when opioid dose reaches 50 morphine milligram equivalents daily, when benzodiazepines are combined, or with prior overdose or substance use history.
- Levothyroxine dose recheck timing
- Wait six to eight weeks after any levothyroxine dose adjustment before rechecking TSH, because the pituitary-thyroid axis requires that interval to reach steady state.
- Lipids after statin start
- Recheck a lipid panel four to twelve weeks after starting or changing statin therapy to assess adherence, treatment response, and need for intensification.
- A1c monitoring frequency
- Check A1c every three months when therapy is changing or goals are unmet, and every six months once glycemic targets are stable and achieved.
- Warfarin INR monitoring
- Check INR at least weekly during initiation and after dose changes, then every four weeks once stable; target is 2 to 3 for atrial fibrillation.
- Hypoglycemia risk with sulfonylureas
- Sulfonylureas and insulin cause most severe hypoglycemia in older adults; deprescribe or deintensify when A1c falls below 7 percent on these agents.
- Home blood pressure protocol
- Take two readings morning and evening for seven days with a validated upper-arm cuff; average the second week's values and exclude the first day.