AOBPa Pathology study materials
AOBPa Pathology study resources

AOBPa Pathology study plan

AOBPa Pathology · Give each week a clear focus.

8 weeks · About 7 hours per week

Week 1

Anatomic Pathology

  • Map the major organ-system categories of anatomic pathology to the exam blueprint and rank them by weight

  • Describe the morphologic hallmarks and diagnostic criteria for the highest-yield neoplastic and non-neoplastic entities in each organ system

  • Differentiate benign from malignant histologic features using defined criteria for each organ system

  • Build a one-page comparison table of grading and staging conventions across organ systems

Your checkpoint

A completed organ-system matrix (rows = systems, columns = hallmark entities, key stains, grading/staging rule) covering at least 10 systems, self-quizzed to 80% recall.

Week 2

Anatomic Pathology

  • Interpret gross and microscopic descriptions of inflammatory, reactive, and metaplastic processes and predict the expected histologic pattern

  • Correlate immunohistochemical staining panels with lineage and diagnostic utility for common tumors

  • Explain the pathogenesis and morphologic consequences of vascular, degenerative, and metabolic processes

  • Practice discriminating among morphologically similar entities using a structured differential approach

Your checkpoint

A 30-question self-written case set (gross + microscopic description, no images) with answer rationale, scored at 80% or better.

Week 3

Surgical Pathology

  • Apply frozen-section decision logic to margin assessment and diagnostic dilemmas in common surgical specimens

  • Outline the pathologic workup and reporting elements for the most frequently tested resection specimens

  • Differentiate reactive from neoplastic processes in gastrointestinal, dermatologic, and breast specimens

  • Construct synoptic-style reports from narrative case descriptions for at least five specimen types

Your checkpoint

Five completed synoptic-style reports written from narrative scenarios, cross-checked against a self-generated checklist of required reporting elements.

Week 4

Surgical Pathology & Clinical Pathology / Laboratory Medicine

  • Analyze handling and triage decisions for intraoperative consultations and identify when deferral is appropriate

  • Interpret core laboratory panels (chemistry, urinalysis, body fluids) and connect abnormal results to underlying pathology

  • Explain quality-control and preanalytical variables that alter laboratory results

  • Integrate surgical pathology findings with laboratory data in combined case scenarios

Your checkpoint

A 25-item integrated case set linking a surgical pathology scenario to at least one laboratory panel, with a written justification for each answer, scored at 75% or better.

Week 5

Clinical Pathology / Laboratory Medicine

  • Differentiate anemias and coagulopathies by interpreting CBC indices, peripheral smear descriptions, and coagulation studies

  • Evaluate transfusion medicine scenarios including compatibility, reaction workup, and component selection

  • Interpret endocrine, renal, and hepatic laboratory profiles and predict the associated pathologic states

  • Explain the laboratory approach to body fluid analysis and identify transudate versus exudate criteria

Your checkpoint

A two-page laboratory interpretation algorithm sheet plus a 20-question self-test on clinical pathology, scored at 80% or better.

Week 6

Hematopathology & Cytopathology

  • Classify hematologic malignancies using morphologic, immunophenotypic, and cytogenetic criteria described in text-only vignettes

  • Differentiate benign from malignant cytologic preparations using cellularity, nuclear features, and background criteria

  • Apply Bethesda-style reporting logic and adequacy criteria to cytology scenarios

  • Distinguish reactive lymphadenopathy from lymphoma using described architecture and immunophenotype

Your checkpoint

A 20-item combined hematopathology and cytopathology question set with written diagnostic reasoning, scored at 80% or better.

Week 7

Molecular and Genetic Pathology & Microbiology and Infectious Disease Pathology

  • Interpret common molecular testing modalities and match them to clinical indications described in case vignettes

  • Explain the principles of inherited cancer syndromes and the pathologic implications of germline testing

  • Identify the characteristic histologic and laboratory findings of high-yield bacterial, mycobacterial, fungal, and viral infections

  • Select appropriate microbiologic and molecular testing strategies for described clinical scenarios

Your checkpoint

A one-page molecular/infectious disease quick-reference sheet plus a 20-question self-test, scored at 80% or better.

Week 8

Osteopathic Principles and Practice in Pathology & Anatomic Pathology & Clinical Pathology / Laboratory Medicine & Surgical Pathology & Cytopathology & Hematopathology & Molecular and Genetic Pathology & Microbiology and Infectious Disease Pathology

  • Integrate osteopathic principles of structure-function and somatic dysfunction into pathology case reasoning

  • Synthesize all domains through timed mixed-topic practice sets

  • Identify and remediate the three weakest domains based on practice-set performance

  • Consolidate high-yield facts into a single review document for final pass

Your checkpoint

A timed 60-question mixed-domain practice exam completed with a written remediation plan for any domain scoring below 75%.

Milestones

Week 2: Organ-system matrix complete and the 30-question anatomic pathology case set scored at 80% or better.

Week 4: Five synoptic reports completed and the integrated surgical/clinical pathology case set scored at 75% or better.

Week 6: Clinical pathology algorithm sheet finished, and combined hematopathology/cytopathology self-test scored at 80% or better.

Week 8: Timed 60-question mixed-domain exam completed with all domains at or above 75% and a written remediation plan for any that fall short.