CENP key terms
CENP · Get comfortable with the vocabulary.
- Pretest probability
- Related: Likelihood ratio, Clinical decision rule
The estimated chance that a patient has a particular condition before a test result is known, based on history, examination, and local prevalence. It helps decide whether testing will change management.
- Likelihood ratio
- Related: Pretest probability
A statistic that shows how much a test result multiplies the odds of having a disease. Values far from 1.0 strongly shift suspicion; values near 1.0 barely change it.
- Clinical decision rule
- Related: Pretest probability, Red flag
A validated tool that combines history, examination, or test findings to estimate risk and guide decisions such as imaging or discharge. It should be applied only to similar populations.
- Red flag
- Related: Clinical decision rule, Differential diagnosis
A symptom, sign, or history detail that warns of serious underlying disease and calls for urgent evaluation or escalation, even when the patient appears stable.
- Differential diagnosis
- Related: Red flag, Pretest probability
An ordered list of possible causes for a patient's presentation, ranked by likelihood and by danger. It is updated as new history, examination, and test information becomes available.
- Sepsis
- Related: Septic shock, Sepsis bundle, Lactate
Life-threatening organ dysfunction caused by a dysregulated body response to infection. Early recognition, cultures, antibiotics, and careful fluid resuscitation improve the chance of survival.
- Septic shock
- Related: Sepsis, Lactate
Sepsis with persistent low blood pressure that requires vasopressor medication and ongoing evidence of poor perfusion despite adequate fluids. It is a high-mortality emergency needing rapid, coordinated care.
- Lactate
- Related: Sepsis, Septic shock
A blood marker that rises when tissues lack oxygen, commonly measured in sepsis and shock. Serial values help guide resuscitation and can reveal hidden hypoperfusion.
- Sepsis bundle
- Related: Sepsis, Lactate
A set of time-targeted actions for suspected sepsis, such as drawing cultures, giving antibiotics, measuring lactate, and providing fluids. Bundles standardize early treatment and improve outcomes.
- Anaphylaxis
- Related: Red flag
A severe, rapidly progressing allergic reaction that can compromise the airway, breathing, or circulation, often with skin and gastrointestinal symptoms. Intramuscular epinephrine is the first-line treatment.
- Status epilepticus
- Related: Red flag
Continuous seizure activity lasting five minutes or longer, or repeated seizures without recovery of consciousness. It is a medical emergency requiring immediate benzodiazepines, airway support, and a search for causes.
- Acute coronary syndrome
- Related: Differential diagnosis, Red flag
A group of conditions caused by sudden reduced blood flow to the heart muscle, including unstable angina and myocardial infarction. Immediate ECG, troponin, aspirin, and reperfusion decisions are time-sensitive.
- Primary survey
- Related: Secondary survey, Glasgow Coma Scale
A rapid, ordered check of airway, breathing, circulation, disability, and exposure that identifies and treats immediate threats to life before any detailed examination.
- Secondary survey
- Related: Primary survey, FAST exam
A systematic head-to-toe examination and focused history performed after the primary survey and initial stabilization to find injuries that were not immediately life-threatening.
- FAST exam
- Related: Primary survey, Secondary survey
A bedside ultrasound examination that looks for free fluid in the abdomen, pelvis, and pericardium after trauma. It quickly guides resuscitation and decisions about surgery or further imaging.
- Damage control resuscitation
- Related: Primary survey
A strategy for severe bleeding that emphasizes early blood products, limited crystalloid, warming, and rapid control of the bleeding source rather than large fluid volumes.
- Glasgow Coma Scale
- Related: Primary survey
A score from 3 to 15 based on eye opening, verbal response, and motor response. It quantifies consciousness, guides triage, and helps detect neurologic deterioration over time.
- Compartment syndrome
- Related: Neurovascular assessment, Primary survey
Dangerous pressure buildup inside a closed muscle compartment that reduces blood flow and nerve function. Severe pain, especially with passive stretch, is an early warning sign.
- Neurovascular assessment
- Related: Compartment syndrome
Repeated checks of pulses, color, warmth, capillary refill, sensation, and movement in a limb after injury or procedure. Changes can signal compromised perfusion or nerve damage.
- Rapid sequence intubation
- Related: Procedural sedation, Capnography
A coordinated technique using a sedative and a paralytic to secure the airway quickly while reducing aspiration risk. It requires preoxygenation, equipment checks, and a clear backup plan.
- Procedural sedation
- Related: Rapid sequence intubation, Local anesthetic
Giving sedative or dissociative medication to reduce anxiety and pain during a procedure while preserving airway reflexes and vital functions. Monitoring, rescue equipment, and recovery observation are required.
- Capnography
- Related: Rapid sequence intubation, Procedural sedation
Continuous measurement of exhaled carbon dioxide. A sustained waveform confirms endotracheal tube placement and helps monitor ventilation during sedation and after intubation.
- Defibrillation
An unsynchronized electrical shock delivered to stop a lethal ventricular rhythm such as ventricular fibrillation. Early defibrillation is the most important intervention for out-of-hospital cardiac arrest survival.
- Ultrasound-guided IV
Using bedside ultrasound to see a vein and guide needle insertion when traditional palpation or landmark access fails. It improves success in patients with difficult intravenous access.
- Local anesthetic
- Related: Procedural sedation
A medication that blocks nerve conduction to numb a specific area for a procedure. Clinicians must know maximum safe doses and recognize signs of systemic toxicity.
- Pediatric weight-based dosing
- Related: Neonatal fever
Calculating medication doses and equipment sizes from a child's weight, often with a length-based tape during emergencies. Independent double-checks help prevent dangerous dosing errors.
- Geriatric atypical presentation
- Related: Polypharmacy
Older adults may show confusion, weakness, falls, or poor appetite instead of classic symptoms of serious illness. A lower threshold for testing and reassessment is appropriate.
- Polypharmacy
- Related: Geriatric atypical presentation
The use of multiple medications, often five or more, which increases the risk of interactions, adverse effects, and falls. Medication reconciliation is an important safety step in emergency care.
- Pregnancy physiologic changes
Normal adaptations such as higher blood volume, heart rate, and breathing, and lower lung residual volume, that alter baseline vital signs and laboratory values. They can mask clinical deterioration.
- Neonatal fever
- Related: Sepsis, Pediatric weight-based dosing, Red flag
Fever in an infant younger than 28 days is a red flag for serious bacterial infection and usually requires a full sepsis evaluation and hospitalization.
- EMTALA
- Related: Medical screening examination, Scope of practice
A U.S. law requiring hospitals with emergency departments to provide a medical screening examination and stabilizing treatment regardless of insurance status or ability to pay.
- Medical screening examination
- Related: EMTALA
The evaluation a qualified clinician performs to determine whether an emergency medical condition exists, as required before transfer or financial discussion under EMTALA.
- Scope of practice
- Related: EMTALA, Just culture
The activities, procedures, and responsibilities a clinician is legally and professionally authorized to perform under state law and organizational policy.
- Just culture
- Related: Scope of practice
An organizational approach that treats human error as a system issue while holding people accountable for reckless choices. It encourages reporting and learning from adverse events.
- ED boarding
Holding admitted patients in the emergency department while they wait for an inpatient bed. It lengthens stays, worsens crowding, and delays care for newly arriving patients.
- Teach-back
- Related: Health literacy, Shared decision-making
A communication method in which the patient explains information back in their own words. The clinician can then confirm understanding and correct any misunderstandings.
- Health literacy
- Related: Teach-back
A person's ability to obtain, understand, and use health information to make decisions. Low health literacy is common and calls for plain language, pictures, and checks of understanding.
- Motivational interviewing
- Related: Harm reduction, Shared decision-making
A patient-centered counseling style using open questions, affirmations, reflections, and summaries to strengthen a person's own motivation for behavior change. It supports rather than directs.
- Shared decision-making
- Related: Teach-back, Health literacy
A conversation in which clinician and patient compare options using the best evidence and the patient's values, preferences, and circumstances. It is useful when choices are preference-sensitive.
- Harm reduction
- Related: Motivational interviewing
Practical strategies that reduce the harms of risky behavior without requiring abstinence, such as naloxone distribution or sterile syringe access. It meets people where they are.