CENP study materials
CENP study resources

CENP key terms

CENP · Get comfortable with the vocabulary.

Pretest probability

The estimated chance that a patient has a particular condition before a test result is known, based on history, examination, and local prevalence. It helps decide whether testing will change management.

Related: Likelihood ratio, Clinical decision rule
Likelihood ratio

A statistic that shows how much a test result multiplies the odds of having a disease. Values far from 1.0 strongly shift suspicion; values near 1.0 barely change it.

Related: Pretest probability
Clinical decision rule

A validated tool that combines history, examination, or test findings to estimate risk and guide decisions such as imaging or discharge. It should be applied only to similar populations.

Related: Pretest probability, Red flag
Red flag

A symptom, sign, or history detail that warns of serious underlying disease and calls for urgent evaluation or escalation, even when the patient appears stable.

Related: Clinical decision rule, Differential diagnosis
Differential diagnosis

An ordered list of possible causes for a patient's presentation, ranked by likelihood and by danger. It is updated as new history, examination, and test information becomes available.

Related: Red flag, Pretest probability
Sepsis

Life-threatening organ dysfunction caused by a dysregulated body response to infection. Early recognition, cultures, antibiotics, and careful fluid resuscitation improve the chance of survival.

Related: Septic shock, Sepsis bundle, Lactate
Septic shock

Sepsis with persistent low blood pressure that requires vasopressor medication and ongoing evidence of poor perfusion despite adequate fluids. It is a high-mortality emergency needing rapid, coordinated care.

Related: Sepsis, Lactate
Lactate

A blood marker that rises when tissues lack oxygen, commonly measured in sepsis and shock. Serial values help guide resuscitation and can reveal hidden hypoperfusion.

Related: Sepsis, Septic shock
Sepsis bundle

A set of time-targeted actions for suspected sepsis, such as drawing cultures, giving antibiotics, measuring lactate, and providing fluids. Bundles standardize early treatment and improve outcomes.

Related: Sepsis, Lactate
Anaphylaxis

A severe, rapidly progressing allergic reaction that can compromise the airway, breathing, or circulation, often with skin and gastrointestinal symptoms. Intramuscular epinephrine is the first-line treatment.

Related: Red flag
Status epilepticus

Continuous seizure activity lasting five minutes or longer, or repeated seizures without recovery of consciousness. It is a medical emergency requiring immediate benzodiazepines, airway support, and a search for causes.

Related: Red flag
Acute coronary syndrome

A group of conditions caused by sudden reduced blood flow to the heart muscle, including unstable angina and myocardial infarction. Immediate ECG, troponin, aspirin, and reperfusion decisions are time-sensitive.

Related: Differential diagnosis, Red flag
Primary survey

A rapid, ordered check of airway, breathing, circulation, disability, and exposure that identifies and treats immediate threats to life before any detailed examination.

Related: Secondary survey, Glasgow Coma Scale
Secondary survey

A systematic head-to-toe examination and focused history performed after the primary survey and initial stabilization to find injuries that were not immediately life-threatening.

Related: Primary survey, FAST exam
FAST exam

A bedside ultrasound examination that looks for free fluid in the abdomen, pelvis, and pericardium after trauma. It quickly guides resuscitation and decisions about surgery or further imaging.

Related: Primary survey, Secondary survey
Damage control resuscitation

A strategy for severe bleeding that emphasizes early blood products, limited crystalloid, warming, and rapid control of the bleeding source rather than large fluid volumes.

Related: Primary survey
Glasgow Coma Scale

A score from 3 to 15 based on eye opening, verbal response, and motor response. It quantifies consciousness, guides triage, and helps detect neurologic deterioration over time.

Related: Primary survey
Compartment syndrome

Dangerous pressure buildup inside a closed muscle compartment that reduces blood flow and nerve function. Severe pain, especially with passive stretch, is an early warning sign.

Related: Neurovascular assessment, Primary survey
Neurovascular assessment

Repeated checks of pulses, color, warmth, capillary refill, sensation, and movement in a limb after injury or procedure. Changes can signal compromised perfusion or nerve damage.

Related: Compartment syndrome
Rapid sequence intubation

A coordinated technique using a sedative and a paralytic to secure the airway quickly while reducing aspiration risk. It requires preoxygenation, equipment checks, and a clear backup plan.

Related: Procedural sedation, Capnography
Procedural sedation

Giving sedative or dissociative medication to reduce anxiety and pain during a procedure while preserving airway reflexes and vital functions. Monitoring, rescue equipment, and recovery observation are required.

Related: Rapid sequence intubation, Local anesthetic
Capnography

Continuous measurement of exhaled carbon dioxide. A sustained waveform confirms endotracheal tube placement and helps monitor ventilation during sedation and after intubation.

Related: Rapid sequence intubation, Procedural sedation
Defibrillation

An unsynchronized electrical shock delivered to stop a lethal ventricular rhythm such as ventricular fibrillation. Early defibrillation is the most important intervention for out-of-hospital cardiac arrest survival.

Ultrasound-guided IV

Using bedside ultrasound to see a vein and guide needle insertion when traditional palpation or landmark access fails. It improves success in patients with difficult intravenous access.

Local anesthetic

A medication that blocks nerve conduction to numb a specific area for a procedure. Clinicians must know maximum safe doses and recognize signs of systemic toxicity.

Related: Procedural sedation
Pediatric weight-based dosing

Calculating medication doses and equipment sizes from a child's weight, often with a length-based tape during emergencies. Independent double-checks help prevent dangerous dosing errors.

Related: Neonatal fever
Geriatric atypical presentation

Older adults may show confusion, weakness, falls, or poor appetite instead of classic symptoms of serious illness. A lower threshold for testing and reassessment is appropriate.

Related: Polypharmacy
Polypharmacy

The use of multiple medications, often five or more, which increases the risk of interactions, adverse effects, and falls. Medication reconciliation is an important safety step in emergency care.

Related: Geriatric atypical presentation
Pregnancy physiologic changes

Normal adaptations such as higher blood volume, heart rate, and breathing, and lower lung residual volume, that alter baseline vital signs and laboratory values. They can mask clinical deterioration.

Neonatal fever

Fever in an infant younger than 28 days is a red flag for serious bacterial infection and usually requires a full sepsis evaluation and hospitalization.

Related: Sepsis, Pediatric weight-based dosing, Red flag
EMTALA

A U.S. law requiring hospitals with emergency departments to provide a medical screening examination and stabilizing treatment regardless of insurance status or ability to pay.

Related: Medical screening examination, Scope of practice
Medical screening examination

The evaluation a qualified clinician performs to determine whether an emergency medical condition exists, as required before transfer or financial discussion under EMTALA.

Related: EMTALA
Scope of practice

The activities, procedures, and responsibilities a clinician is legally and professionally authorized to perform under state law and organizational policy.

Related: EMTALA, Just culture
Just culture

An organizational approach that treats human error as a system issue while holding people accountable for reckless choices. It encourages reporting and learning from adverse events.

Related: Scope of practice
ED boarding

Holding admitted patients in the emergency department while they wait for an inpatient bed. It lengthens stays, worsens crowding, and delays care for newly arriving patients.

Teach-back

A communication method in which the patient explains information back in their own words. The clinician can then confirm understanding and correct any misunderstandings.

Related: Health literacy, Shared decision-making
Health literacy

A person's ability to obtain, understand, and use health information to make decisions. Low health literacy is common and calls for plain language, pictures, and checks of understanding.

Related: Teach-back
Motivational interviewing

A patient-centered counseling style using open questions, affirmations, reflections, and summaries to strengthen a person's own motivation for behavior change. It supports rather than directs.

Related: Harm reduction, Shared decision-making
Shared decision-making

A conversation in which clinician and patient compare options using the best evidence and the patient's values, preferences, and circumstances. It is useful when choices are preference-sensitive.

Related: Teach-back, Health literacy
Harm reduction

Practical strategies that reduce the harms of risky behavior without requiring abstinence, such as naloxone distribution or sterile syringe access. It meets people where they are.

Related: Motivational interviewing