Arab Board Internal Medicine Clinical Exam flashcards
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- STEMI reperfusion window
- Primary PCI is preferred within 120 minutes of first medical contact; fibrinolysis is an alternative when PCI is unavailable and symptom onset is under 12 hours without contraindications.
- CHA2DS2-VASc anticoagulation threshold
- Oral anticoagulation is recommended for atrial fibrillation when the score is at least 2 in men or 3 in women; DOACs are preferred except with mechanical valves or moderate-severe mitral stenosis.
- Light criteria exudate
- Pleural fluid is exudative if protein ratio exceeds 0.5, LDH ratio exceeds 0.6, or pleural LDH exceeds two-thirds the upper normal serum limit.
- CURB-65 components
- Confusion, urea above 7 mmol/L, respiratory rate at least 30, systolic BP below 90 or diastolic at most 60, and age at least 65; a score of 2 or more supports admission.
- Spontaneous bacterial peritonitis threshold
- An ascitic fluid neutrophil count of at least 250 per cubic millimeter is diagnostic; treat with a third-generation cephalosporin and add albumin when creatinine exceeds 1 mg/dL.
- Acute severe ulcerative colitis
- Defined by at least six bloody stools per day plus systemic toxicity; intravenous corticosteroids are first-line with rescue infliximab or colectomy for nonresponse.
- KDIGO AKI creatinine criteria
- AKI is a creatinine rise of 1.5 to 1.9 times baseline, 2.0 to 2.9 times, or at least 3 times, or a rise to at least 354 micromol/L.
- Hyponatremia correction limit
- Correct chronic hyponatremia by no more than 8 to 10 mmol/L in 24 hours to avoid osmotic demyelination; acute symptomatic cases may need faster initial correction.
- Diabetic ketoacidosis potassium rule
- Replace potassium once serum potassium is below 5.5 mmol/L; add dextrose when glucose falls below 14 mmol/L so the insulin infusion can continue.
- Thyroid storm treatment sequence
- Give a beta-blocker, then a thionamide, then iodine after the thionamide, plus corticosteroids; a Burch-Wartofsky score of 45 or more suggests thyroid storm.
- Heparin-induced thrombocytopenia
- Platelet count falls by at least 50 percent typically 5 to 10 days after heparin exposure with high thrombosis risk; stop heparin and start a non-heparin anticoagulant.
- Neutropenic fever definition
- A single oral temperature of at least 38.3 degrees Celsius, or at least 38.0 sustained over one hour, in a neutropenic patient; start antipseudomonal antibiotics within one hour.
- Sepsis antibiotic timing
- Obtain cultures then give broad-spectrum antibiotics within one hour for septic shock; for possible sepsis without shock, complete evaluation within three hours.
- Severe falciparum malaria treatment
- Severe disease with parasitemia above 5 percent, acidosis, or cerebral involvement requires intravenous artesunate; uncomplicated cases use artemisinin-based combination therapy.
- Gout crystal finding
- Negatively birefringent needle-shaped monosodium urate crystals confirm gout; urate-lowering therapy targets serum urate below 360 micromol/L.
- Giant cell arteritis urgency
- Start high-dose corticosteroids immediately when giant cell arteritis is suspected to prevent vision loss; temporal artery biopsy confirms but must not delay treatment.
- Status epilepticus sequence
- Give a benzodiazepine first, then a second-line agent such as levetiracetam, valproate, or phenytoin; refractory cases require anesthetic infusion.
- Berlin ARDS criteria
- Onset within one week, bilateral infiltrates not explained by cardiac failure, and PaO2/FiO2 of 300 mmHg or less on PEEP of at least 5 cmH2O.
- Septic shock initial resuscitation
- Give 30 mL/kg crystalloid within the first three hours, then start norepinephrine to target a mean arterial pressure of at least 65 mmHg.
- Statin target in ASCVD
- High-intensity statin therapy for established atherosclerotic cardiovascular disease, targeting LDL cholesterol below 1.8 mmol/L.
- Beers criteria purpose
- Identifies potentially inappropriate medications in older adults, including anticholinergics, benzodiazepines, and long-acting sulfonylureas, to guide deprescribing.
- Heart failure four pillars
- For reduced ejection fraction, combine an ARNI or ACE inhibitor, an evidence-based beta-blocker, a mineralocorticoid receptor antagonist, and an SGLT2 inhibitor to reduce mortality.
- Tension pneumothorax management
- Tension pneumothorax is a clinical diagnosis; perform immediate needle decompression followed by chest tube insertion without waiting for imaging.
- Hepatorenal syndrome treatment
- Functional renal failure in cirrhosis treated first-line with terlipressin plus albumin; exclude hypovolemia with a volume challenge and avoid nephrotoxins.
- Metabolic acidosis anion gap
- Anion gap equals sodium minus the sum of chloride and bicarbonate; a high gap suggests ketoacidosis, lactic acidosis, renal failure, or toxins.
- Adrenal crisis treatment
- Give intravenous hydrocortisone immediately, 100 mg then 50 mg every six hours, with saline; do not delay treatment for cortisol results when suspected.
- Tumor lysis syndrome features
- Hyperkalemia, hyperphosphatemia, hyperuricemia, and hypocalcemia; prevent with hydration and allopurinol, or rasburicase in high-risk patients.
- HIV post-exposure prophylaxis
- Start a three-drug antiretroviral regimen within 72 hours of exposure and continue for 28 days; test the source and baseline serology.
- Anaphylaxis first-line drug
- Intramuscular adrenaline 0.5 mg of 1:1000 solution into the anterolateral thigh, repeated every five minutes as needed; adjuncts include fluids and antihistamines.
- Ischemic stroke thrombolysis window
- Intravenous thrombolysis within 4.5 hours of onset if non-contrast CT excludes hemorrhage and no contraindication exists; thrombectomy for large vessel occlusion in selected patients.
- Hyperkalemia emergency sequence
- Give intravenous calcium for membrane stabilization, then insulin-glucose and salbutamol to shift potassium, and remove potassium with binders or dialysis.
- Alcohol withdrawal treatment
- Use symptom-triggered benzodiazepines guided by the CIWA-Ar score, and give thiamine before glucose to prevent Wernicke encephalopathy.