Arab Board Oncology Part 1 case studies
Arab Board Oncology Part 1 · Put your knowledge to work in context.
The Arab Board Oncology Part 1 is the basic-sciences component of specialty training in oncology within the Arab Board system. It is intended for physicians who are preparing to enter or progress through oncology training and who need to demonstrate a secure foundation in the science that underpins daily cancer practice. The Arab Board Oncology Part 1 case studies are 5 cases and about 2,607 words.
1Grade 3 immune-mediated colitis on combination immunotherapy
A 62-year-old man with BRAF V600E-mutant metastatic melanoma begins nivolumab plus ipilimumab. On day 18 he reports six to eight watery stools daily for three days, crampy abdominal pain, and one episode of vomiting.
544 words, about 3 min2Interpreting a positive PFS trial with immature overall survival
A phase III trial randomizes 600 patients with advanced biliary tract cancer to FOLFOX alone or FOLFOX plus durvalumab. At the first interim analysis, median progression-free survival is 7.1 months with durvalumab versus 5.3 months with chemotherapy alone (HR 0.74, 95% CI 0.60–0.91; p=0.004).
535 words, about 3 min3Neutropenic septic shock with a penicillin allergy label
A 58-year-old woman with newly diagnosed acute myeloid leukemia is day 12 after induction chemotherapy. She presents with rigors, temperature 38.6°C, blood pressure 86/52 mmHg, heart rate 124/min, respiratory rate 26/min, and lactate 3.9 mmol/L.
507 words, about 3 min4Family request for nondisclosure in a patient with delirium and brain metastases
An 81-year-old man with newly diagnosed metastatic pancreatic cancer and a recent cerebral metastasis is admitted with confusion. He speaks Cantonese and understands little English.
498 words, about 2 min5Re-irradiation of a painful vertebral metastasis with a prior cord dose
A 55-year-old woman with hormone receptor-positive metastatic breast cancer has a painful T8 vertebral metastasis. Fourteen months ago she received 30 Gy in 10 fractions to T7–T9 for a different lesion; the spinal cord maximum was 27 Gy.
523 words, about 3 min