Arab Board Psychiatry Clinical Exam cheat sheet
Arab Board Psychiatry Clinical Exam · Keep the key ideas within reach.
Clinical Interviewing and Psychiatric Assessment
Mental status examination components: appearance, behaviour, speech, mood, affect, thought form and content, perception, cognition, insight, judgement.
Cognitive screen domains: orientation, attention/concentration, memory (immediate, recent, remote), language, visuospatial, executive function; MMSE threshold ≤23/30 suggests impairment, MoCA ≤25/30.
Delirium screen (CAM): acute onset/fluctuating course PLUS inattention PLUS either disorganised thinking or altered consciousness.
Screening cut-offs: PHQ-9 ≥10 moderate depression; GAD-7 ≥10 moderate anxiety; AUDIT ≥8 hazardous drinking; CAGE ≥2 clinically significant.
Suicide risk assessment structure: ideation, plan, intent, means, prior attempts, protective factors, and documented risk formulation.
Collateral history from family/carers is required when cognition, insight, or psychosis limits the patient's reliability.
Capacity (four abilities): understand, retain, weigh/use information, and communicate a choice; assessed per decision, not globally.
Substance history: quantity, frequency, duration, route, last use, withdrawal history, and treatment attempts.
Psychopathology and Diagnostic Formulation
Thought disorder signs: derailment, loosening of associations, neologisms, word salad, clang associations, thought blocking.
First-rank (Schneiderian) symptoms: auditory hallucinations discussing/commenting, thought insertion/withdrawal/broadcast, passivity phenomena, delusional perception.
Delusion vs overvalued idea: delusion is fixed and held with unshakeable conviction despite contrary evidence; overvalued idea is less rigid but dominant.
Formulation sections: predisposing, precipitating, perpetuating, protective factors, plus differential diagnosis and management plan.
Negative symptoms: affective flattening, alogia, avolition, anhedonia, asociality; distinguish from depression and medication effects.
Insight dimensions: awareness of illness, need for treatment, and attribution of symptoms; impaired insight predicts non-adherence.
Clinical staging: prodrome, acute episode, remission, relapse; document baseline functioning to interpret change.
Diagnostic criteria require duration, functional impact, and exclusion of substance/medical causes before primary psychiatric diagnosis.
Psychotic Disorders
Schizophrenia requires ≥2 core symptoms (delusions, hallucinations, disorganised speech, grossly disorganised/catatonic behaviour, negative symptoms) with ≥1 from first three, continuous signs ≥6 months, and functional decline.
Brief psychotic disorder: duration ≥1 day but <1 month with full return to baseline; schizophreniform: ≥1 month but <6 months.
Schizoaffective disorder: mood episode concurrent with psychotic symptoms for majority of illness, plus ≥2 weeks delusions/hallucinations without prominent mood symptoms.
Delusional disorder: delusions ≥1 month, functioning relatively preserved, behaviour not obviously odd apart from delusion.
Substance/medication-induced psychosis requires symptoms during or shortly after intoxication/withdrawal and resolution with abstinence.
Antipsychotic response typically takes 2–4 weeks; 20–30% show treatment resistance (≥2 adequate trials of different antipsychotics).
Clozapine is indicated in treatment-resistant schizophrenia; monitor FBC weekly for 18 weeks then fortnightly, and check for agranulocytosis and myocarditis.
Acute dystonia is treated with anticholinergics (e.g., procyclidine) or benzodiazepines; akathisia with dose reduction or beta-blocker.
Mood Disorders
Major depressive episode: ≥5 of 9 symptoms for ≥2 weeks, including depressed mood or anhedonia; SIGECAPS mnemonic lists the symptoms.
Manic episode: ≥1 week of elevated/irritable mood with ≥3 (or ≥4 if irritable) of: grandiosity, decreased need for sleep, pressured speech, flight of ideas, distractibility, increased activity, risky behaviour.
Hypomania: ≥4 days, observable change, no marked functional impairment, no psychosis; does not require hospitalisation.
Bipolar I requires ≥1 manic episode; bipolar II requires hypomania plus major depression, never full mania.
Rapid cycling: ≥4 mood episodes in 12 months; more common in women and predicts poorer lithium response.
Serotonin syndrome triad: altered mental status, autonomic instability, neuromuscular hyperactivity (clonus, hyperreflexia); stop serotonergic agents.
Lithium monitoring: target trough 0.6–0.8 mmol/L (0.4–0.6 in elderly); check renal and thyroid function regularly; toxicity risk with dehydration and NSAIDs.
ECT indications: severe depression with psychosis, catatonia, life-threatening refusal of food/fluid, and treatment resistance.
Anxiety, Obsessive-Compulsive and Trauma-Related Disorders
Panic attack: abrupt surge of intense fear peaking within minutes with ≥4 of 13 symptoms; panic disorder requires recurrent unexpected attacks plus ≥1 month of worry/behaviour change.
Agoraphobia: fear of ≥2 situations (public transport, open spaces, enclosed places, crowds, being outside alone) due to escape difficulty.
Social anxiety disorder: fear of negative evaluation in social situations, ≥6 months, causing avoidance or distress.
OCD: obsessions and/or compulsions that are time-consuming (>1 hour/day) or cause distress/impairment; insight specifier (good/fair, poor, absent/delusional).
First-line OCD treatment: SSRIs at higher doses (e.g., fluoxetine 40–60 mg) plus exposure and response prevention (ERP) CBT.
PTSD requires exposure to trauma plus ≥1 intrusion, ≥1 avoidance, ≥2 negative cognition/mood, ≥2 arousal/reactivity symptoms, >1 month, with functional impairment.
Acute stress disorder: 3 days to 1 month post-trauma; PTSD: >1 month.
First-line PTSD psychotherapy: trauma-focused CBT or EMDR; SSRIs (sertraline, paroxetine) are first-line pharmacotherapy.
Substance Use Disorders and Addictions
DSM-5 SUD criteria cluster into impaired control, social impairment, risky use, and pharmacological criteria (tolerance, withdrawal); ≥2 criteria = disorder, severity 2–3 mild, 4–5 moderate, ≥6 severe.
Alcohol withdrawal timeline: tremor/anxiety 6–12 h, seizures 12–48 h, delirium tremens 48–96 h; treat with benzodiazepines (chlordiazepoxide or diazepam) using symptom-triggered CIWA-Ar.
Wernicke encephalopathy triad: confusion, ataxia, ophthalmoplegia; give IV thiamine before glucose to prevent Wernicke–Korsakoff.
Opioid use disorder: first-line maintenance with buprenorphine or methadone; naltrexone is an alternative after detoxification.
Nicotine dependence: varenicline and combination NRT are first-line; bupropion is an alternative; combine with behavioural support.
Benzodiazepine withdrawal can cause seizures and delirium; taper gradually, never stop abruptly after long-term use.
Cannabis hyperemesis syndrome: recurrent vomiting, abdominal pain, relief with hot showers; resolves with cessation.
Screening tools: AUDIT for alcohol, CAGE for brief screen, DAST for drugs; urine drug screen detects metabolites with variable windows.
Neurocognitive, Organic and Consultation-Liaison Psychiatry
Delirium is a medical emergency: identify and treat the underlying cause (infection, drugs, metabolic, hypoxia, pain, urinary retention, constipation); use antipsychotics cautiously for severe agitation.
Dementia vs delirium: dementia has insidious onset, preserved consciousness, and progressive decline; delirium has acute onset, fluctuating course, and impaired attention.
Alzheimer's disease: earliest deficit is episodic memory (hippocampal); treat with cholinesterase inhibitors (donepezil, rivastigmine, galantamine) in mild-moderate disease; memantine in moderate-severe.
Frontotemporal dementia: early personality/behaviour change or language impairment with relatively preserved memory; behavioural variant most common.
Lewy body dementia: fluctuating cognition, visual hallucinations, parkinsonism, REM sleep behaviour disorder; severe neuroleptic sensitivity.
Vascular dementia: stepwise decline, focal neurological signs, cerebrovascular risk factors; prevent with vascular risk management.
Serotonin syndrome vs NMS: NMS has rigidity, hyperthermia, autonomic instability, elevated CK, and is caused by dopamine antagonists; serotonin syndrome has clonus and hyperreflexia.
Consultation-liaison: screen for depression in chronic illness, assess capacity for treatment refusal, and manage delirium in medically ill inpatients.
Child and Adolescent Psychiatry
ADHD: ≥6 inattentive or hyperactive/impulsive symptoms for ≥6 months, onset before age 12, present in ≥2 settings, causing impairment.
Autism spectrum disorder: persistent deficits in social communication/interaction plus restricted, repetitive behaviours/interests, present in early development.
First-line ADHD pharmacotherapy: stimulants (methylphenidate, amphetamines); monitor height, weight, blood pressure, and cardiac history.
Separation anxiety disorder: developmentally inappropriate fear of separation from attachment figures, ≥4 weeks in children, causing distress/impairment.
Conduct disorder vs oppositional defiant disorder: ODD is a pattern of angry/irritable mood and defiance without serious violation of others' rights; conduct disorder involves aggression, property destruction, deceit/theft.
Tourette syndrome: multiple motor plus ≥1 vocal tic for >1 year; treat with behavioural therapy (CBIT) or alpha-2 agonists; antipsychotics for severe cases.
Child safeguarding: any suspicion of abuse requires documentation and reporting to child protection authorities regardless of parental consent.
Adolescent depression: assess for self-harm and substance use; fluoxetine is the only SSRI licensed for adolescent depression in many jurisdictions.
Psychopharmacology and Somatic Treatments
SSRIs: first-line for depression, anxiety, OCD, PTSD; onset 2–4 weeks; common side effects include GI upset, sexual dysfunction, hyponatraemia in elderly.
Serotonin syndrome risk increases with combinations of SSRIs, MAOIs, tramadol, triptans, and linezolid; MAOIs require 14-day washout before/after SSRIs.
Antipsychotic metabolic monitoring: baseline and periodic weight, BMI, waist, blood pressure, fasting glucose/HbA1c, and lipids.
Clozapine: monitor FBC weekly for 18 weeks then fortnightly; contraindicated in previous agranulocytosis; check for myocarditis in first 2 months.
Lithium: narrow therapeutic index; target 0.6–0.8 mmol/L; monitor renal function, thyroid, calcium; toxicity presents with tremor, ataxia, confusion, vomiting.
Benzodiazepines: short-term use only (2–4 weeks) due to tolerance, dependence, and withdrawal; avoid in elderly (falls, confusion).
Antidepressant discontinuation syndrome: dizziness, nausea, flu-like symptoms, paraesthesia; taper gradually, especially paroxetine and venlafaxine.
ECT: indications include severe depression with psychosis, catatonia, and life-threatening food refusal; common side effects are transient memory impairment and headache.
Psychotherapy and Psychosocial Interventions
CBT model: thoughts, feelings, and behaviours interact; treatment targets cognitive distortions (catastrophising, all-or-nothing thinking) and behavioural avoidance.
Exposure and response prevention (ERP) is the first-line psychotherapy for OCD; exposure without response prevention is less effective.
Behavioural activation is an evidence-based treatment for depression, focusing on increasing activity and reducing avoidance.
Psychodynamic therapy focuses on unconscious conflict, transference, and defence mechanisms; typically longer-term.
DBT components: mindfulness, distress tolerance, emotion regulation, interpersonal effectiveness; indicated for borderline personality disorder and repeated self-harm.
Motivational interviewing: collaborative, non-judgemental approach to resolve ambivalence; uses open questions, affirmation, reflection, summarising (OARS).
Family therapy and psychoeducation reduce relapse in schizophrenia; expressed emotion (criticism, hostility, over-involvement) predicts relapse.
Group therapy is effective for substance use, anxiety, and psychoeducation; screen for suitability and confidentiality limits.
Risk Assessment, Emergency Psychiatry and Ethics/Professionalism
Suicide risk factors: male sex, older age, prior attempt, family history, substance misuse, access to means, hopelessness, social isolation, recent loss, and physical illness.
Protective factors: social support, reasons for living, engagement with services, children at home, and religious/cultural beliefs.
High-risk features: specific plan, available means, intent, agitation, command hallucinations, and recent discharge from hospital.
Immediate management of acute risk: ensure safety, remove means, consider voluntary or involuntary admission, and document risk formulation and plan.
Capacity assessment: the four abilities (understand, retain, weigh, communicate) apply to the specific decision; if capacity is absent, act in best interests per local law.
Confidentiality limits: risk of serious harm to self or others, child protection, and court order; disclose only necessary information.
Emergency sedation: use the least restrictive option; monitor airway, breathing, circulation, and vital signs; follow local rapid tranquillisation protocol.
Professional boundaries: avoid dual relationships, declare conflicts of interest, maintain accurate records, and obtain informed consent for treatment and research.
Psychotic Disorders
First-episode psychosis: prompt referral to early intervention services improves outcomes; avoid high-dose antipsychotics in first episode.
Positive symptoms: hallucinations, delusions, disorganised thinking; negative symptoms: flat affect, alogia, avolition, anhedonia, asociality.
Antipsychotic choice: consider side-effect profile (metabolic, extrapyramidal, prolactin, QT) and patient preference; monitor adherence.
Treatment-resistant schizophrenia: failure of ≥2 adequate antipsychotic trials; clozapine is the evidence-based next step.
Relapse prevention: continue antipsychotics for at least 1–2 years after first episode and longer after multiple episodes; psychoeducation reduces relapse.
Catatonia: immobility, mutism, negativism, posturing, waxy flexibility; treat with benzodiazepines (lorazepam challenge) and/or ECT.
Neuroleptic malignant syndrome: rigidity, hyperthermia, autonomic instability, elevated CK; stop antipsychotic, supportive care, dantrolene or bromocriptine.
Physical health monitoring in psychosis: cardiovascular risk, metabolic syndrome, smoking, and reduced life expectancy of 15–20 years.
Mood Disorders
Depression severity: mild (few symptoms, minimal impairment), moderate (between), severe (most symptoms, marked impairment, possible psychosis).
Antidepressant selection: consider prior response, side-effect profile, drug interactions, and comorbidities; SSRIs are usually first-line.
Treatment-resistant depression: inadequate response to ≥2 adequate antidepressant trials; consider augmentation (lithium, atypical antipsychotic), switching, or ECT.
Bipolar disorder: avoid antidepressant monotherapy due to switch/rapid cycling risk; use mood stabilisers (lithium, valproate, lamotrigine) and atypical antipsychotics.
Valproate: teratogenic (neural tube defects); avoid in women of childbearing potential unless pregnancy prevention programme in place.
Perinatal depression: assess risk, consider psychological therapy first in mild-moderate cases; SSRIs (sertraline) are commonly used in breastfeeding.
Depression in older adults: screen for cognitive impairment, medical causes (hypothyroidism, anaemia, medications), and suicide risk.
Seasonal affective disorder: light therapy (10,000 lux for 30 minutes daily) is first-line; SSRIs are an alternative.
Anxiety, Obsessive-Compulsive and Trauma-Related Disorders
Generalised anxiety disorder: excessive worry for ≥6 months, difficult to control, with ≥3 of 6 symptoms (restlessness, fatigue, concentration difficulty, irritability, muscle tension, sleep disturbance).
Panic disorder treatment: CBT with interoceptive exposure plus SSRIs; avoid benzodiazepines long-term.
OCD: obsessions are intrusive thoughts/images/urges; compulsions are repetitive behaviours/mental acts performed to reduce distress.
PTSD: trauma-focused CBT and EMDR are first-line; SSRIs are first-line medication; avoid benzodiazepines due to risk of dependence and interference with therapy.
Acute stress reaction: symptoms within hours to days of trauma, usually resolve within days; supportive care and watchful waiting.
Adjustment disorder: emotional/behavioural symptoms within 3 months of a stressor, resolving within 6 months of stressor removal.
Social anxiety disorder: CBT with exposure and cognitive restructuring; SSRIs (sertraline, escitalopram) are first-line medication.
Body dysmorphic disorder: preoccupation with perceived defect, repetitive behaviours, poor insight; treat with SSRIs and CBT.
Substance Use Disorders and Addictions
Alcohol dependence: features include tolerance, withdrawal, craving, loss of control, and continued use despite harm.
Alcohol withdrawal: use CIWA-Ar to guide symptom-triggered benzodiazepine dosing; monitor for seizures and delirium tremens.
Opioid overdose: pinpoint pupils, respiratory depression, reduced consciousness; treat with naloxone and supportive care.
Opioid substitution therapy: methadone and buprenorphine reduce mortality and illicit use; buprenorphine has a ceiling effect and lower overdose risk.
Stimulant use disorder: no approved pharmacotherapy; CBT and contingency management are evidence-based.
Cannabis use disorder: CBT and motivational enhancement; withdrawal symptoms include irritability, insomnia, and decreased appetite.
Dual diagnosis: treat both mental illness and substance use concurrently; integrated treatment improves outcomes.
Harm reduction: needle exchange, supervised consumption, and naloxone distribution reduce morbidity and mortality.
Neurocognitive, Organic and Consultation-Liaison Psychiatry
Delirium: common in hospitalised elderly; causes include infection, medications, metabolic derangement, hypoxia, and withdrawal; use the CAM for detection.
Dementia assessment: history, cognitive testing (MMSE/MoCA), blood tests (B12, thyroid, folate), and neuroimaging to exclude reversible causes.
Reversible causes of cognitive impairment: depression (pseudodementia), hypothyroidism, B12 deficiency, normal pressure hydrocephalus, chronic subdural haematoma.
Alzheimer's disease: cholinesterase inhibitors for mild-moderate; memantine for moderate-severe; behavioural symptoms managed with non-pharmacological approaches first.
Parkinson's disease dementia: occurs >1 year after motor symptoms; dementia with Lewy bodies: cognitive decline before or within 1 year of parkinsonism.
Huntington's disease: autosomal dominant, chorea, cognitive decline, psychiatric symptoms; genetic counselling is essential.
Consultation-liaison: assess for delirium, depression, capacity, and medication interactions in medically ill patients.
Medically unexplained symptoms: assess for underlying psychiatric disorder, provide continuity of care, and avoid unnecessary investigations.
Child and Adolescent Psychiatry
ADHD assessment: multiple informants (parent, teacher), rating scales (Conners, SNAP-IV), and rule out other causes (hearing, sleep, learning disorders).
Autism assessment: developmental history, ADOS-2, and multidisciplinary evaluation; early intervention improves outcomes.
Childhood depression: assess for irritability, somatic complaints, and school refusal; CBT and family therapy are first-line; fluoxetine is first-line medication.
Anxiety in children: separation anxiety, social anxiety, and generalised anxiety are common; CBT is first-line; SSRIs are second-line.
Eating disorders: anorexia nervosa has the highest mortality of psychiatric disorders; monitor weight, electrolytes, and cardiac status; family-based treatment for adolescents.
Self-harm in adolescents: assess risk, underlying mental illness, and family functioning; safety planning and follow-up are essential.
Child protection: mandatory reporting of suspected abuse or neglect; document findings objectively.
Tics: transient tic disorder <1 year; Tourette syndrome >1 year with motor and vocal tics; CBIT is first-line behavioural treatment.
Psychopharmacology and Somatic Treatments
Antidepressant classes: SSRIs, SNRIs, mirtazapine, bupropion, tricyclics, MAOIs; choose based on side effects and interactions.
Tricyclic antidepressants: anticholinergic side effects, cardiotoxicity in overdose; contraindicated in recent MI and arrhythmias.
MAOIs: dietary restriction of tyramine (cheese, cured meats, fermented foods) to prevent hypertensive crisis; avoid sympathomimetics.
Mood stabilisers: lithium (first-line for bipolar), valproate, lamotrigine (depression prophylaxis), carbamazepine; monitor levels and side effects.
Antipsychotics: typical (haloperidol, chlorpromazine) have higher EPS; atypical (risperidone, olanzapine, quetiapine, aripiprazole) have higher metabolic risk.
QTc prolongation: risk with haloperidol, pimozide, quetiapine, and citalopram; monitor ECG in at-risk patients.
Benzodiazepine withdrawal: taper slowly (e.g., 10–25% every 2 weeks); abrupt cessation risks seizures and delirium.
ECT: safe in pregnancy and elderly; consent and capacity considerations; monitor for cognitive side effects.
Psychotherapy and Psychosocial Interventions
CBT: structured, time-limited, collaborative; effective for depression, anxiety, OCD, PTSD, and insomnia.
Psychodynamic psychotherapy: explores unconscious processes, transference, and early relationships; longer-term.
Interpersonal therapy (IPT): focuses on role transitions, grief, disputes, and interpersonal deficits; effective for depression.
DBT: four modules (mindfulness, distress tolerance, emotion regulation, interpersonal effectiveness); for borderline personality disorder.
Motivational interviewing: OARS (open questions, affirmations, reflections, summaries); roll with resistance; support self-efficacy.
Family intervention: psychoeducation, communication skills, and problem-solving; reduces relapse in schizophrenia.
Cognitive remediation: improves cognitive function in schizophrenia; combined with vocational rehabilitation.
Therapeutic alliance: strong alliance predicts better outcomes across therapies; monitor and repair ruptures.
Risk Assessment, Emergency Psychiatry and Ethics/Professionalism
Risk assessment: gather history, current presentation, and collateral; formulate risk (static and dynamic factors) and document management plan.
Suicide risk: ask directly about ideation, plan, intent, and means; assess hopelessness and access to lethal means.
Violence risk: assess history, substance use, psychosis, impulsivity, and access to weapons; use structured tools (HCR-20) where appropriate.
Acute agitation: verbal de-escalation first; if needed, rapid tranquillisation with benzodiazepine and/or antipsychotic; monitor vital signs.
Capacity: assess understanding, retention, weighing, and communication; if lacking, act in best interests under mental health or capacity legislation.
Confidentiality: disclose only with consent or where legally required (risk of serious harm, child protection, court order).
Informed consent: provide information on diagnosis, treatment options, risks, benefits, and alternatives; document discussion.
Professional boundaries: avoid dual relationships, maintain confidentiality, and seek supervision when conflicts arise.
Psychotic Disorders
Schizophrenia: positive, negative, and cognitive symptoms; cognitive deficits predict functional outcome.
Antipsychotic adherence: poor adherence is the strongest predictor of relapse; use long-acting injectable antipsychotics when adherence is problematic.
Metabolic syndrome: monitor weight, waist, blood pressure, glucose, and lipids at baseline and periodically; antipsychotics differ in risk.
Hyperprolactinaemia: risperidone and typical antipsychotics raise prolactin; symptoms include galactorrhoea, amenorrhoea, and sexual dysfunction.
Tardive dyskinesia: involuntary movements (oro-facial); monitor with AIMS; treat by reducing or switching antipsychotic; VMAT2 inhibitors (valbenazine) may help.
Post-psychotic depression: common after acute episode; assess and treat; distinguish from negative symptoms.
Stigma and recovery: psychosocial interventions, supported employment, and family involvement improve outcomes.
Physical health: people with schizophrenia have higher rates of smoking, diabetes, and cardiovascular disease; annual physical health check recommended.
Mood Disorders
Bipolar depression: treat with quetiapine, lurasidone, or lamotrigine; avoid antidepressant monotherapy.
Mixed features: concurrent manic and depressive symptoms; associated with higher suicide risk and poorer response to antidepressants.
Rapid cycling: optimise mood stabiliser, avoid antidepressants, and consider thyroid function.
Lithium: first-line for bipolar maintenance; reduces suicide risk; monitor levels, renal, and thyroid function.
Valproate: effective for mania; avoid in women of childbearing age unless pregnancy prevention; monitor liver function and platelets.
Lamotrigine: effective for bipolar depression prevention; titrate slowly to avoid Stevens-Johnson syndrome.
Perinatal bipolar disorder: high risk of postpartum psychosis; plan pre-conception and monitor closely postpartum.
Depression with psychotic features: antipsychotic plus antidepressant or ECT; ECT is highly effective.
Anxiety, Obsessive-Compulsive and Trauma-Related Disorders
Panic disorder: CBT with interoceptive exposure and cognitive restructuring; SSRIs/SNRIs first-line medication.
GAD: CBT and SSRIs/SNRIs; buspirone is an alternative; benzodiazepines only short-term.
OCD: ERP is first-line psychotherapy; SSRIs at higher doses; clomipramine is an alternative.
PTSD: trauma-focused CBT, EMDR, and SSRIs; avoid benzodiazepines.
Acute stress disorder: symptoms 3 days to 1 month; trauma-focused CBT may prevent PTSD.
Adjustment disorder: symptoms within 3 months of stressor; psychotherapy is first-line.
Social anxiety disorder: CBT with exposure; SSRIs/SNRIs; beta-blockers for performance anxiety.
Body dysmorphic disorder: SSRIs and CBT; often chronic and underdiagnosed.
Substance Use Disorders and Addictions
Alcohol: AUDIT screening; brief intervention for hazardous use; detoxification with benzodiazepines; relapse prevention with acamprosate or naltrexone.
Opioids: methadone and buprenorphine are first-line for opioid use disorder; naltrexone is an alternative.
Nicotine: varenicline, NRT, and bupropion; combine with behavioural support.
Stimulants: CBT and contingency management; no approved pharmacotherapy.
Cannabis: CBT and motivational enhancement; withdrawal symptoms are usually mild.
Benzodiazepines: taper gradually; risk of seizures with abrupt withdrawal.
Dual diagnosis: integrated treatment for mental illness and substance use.
Harm reduction: naloxone distribution, needle exchange, and supervised consumption.
Neurocognitive, Organic and Consultation-Liaison Psychiatry
Delirium: acute onset, fluctuating course, inattention; identify and treat cause; avoid restraints; use antipsychotics cautiously.
Dementia: progressive cognitive decline; assess with MMSE/MoCA; exclude reversible causes.
Alzheimer's disease: cholinesterase inhibitors and memantine; behavioural symptoms managed non-pharmacologically first.
Vascular dementia: stepwise decline; manage vascular risk factors.
Lewy body dementia: fluctuating cognition, visual hallucinations, parkinsonism; avoid typical antipsychotics.
Frontotemporal dementia: personality and language changes; manage behaviour with SSRIs and non-pharmacological approaches.
Consultation-liaison: assess capacity, delirium, depression, and medication interactions.
Medically unexplained symptoms: assess for psychiatric disorder; provide continuity and avoid unnecessary tests.
Child and Adolescent Psychiatry
ADHD: stimulants first-line; monitor growth and cardiovascular status; behavioural interventions.
Autism: early intervention, speech and language therapy, and behavioural support; treat comorbid conditions.
Depression: CBT and family therapy first-line; fluoxetine is first-line medication.
Anxiety: CBT first-line; SSRIs second-line.
Eating disorders: family-based treatment for adolescents with anorexia; monitor medical stability.
Self-harm: assess risk and underlying mental illness; safety planning.
Child protection: mandatory reporting; document objectively.
Tics: CBIT first-line; alpha-2 agonists or antipsychotics for severe cases.
Psychopharmacology and Somatic Treatments
SSRIs: first-line for depression and anxiety; onset 2–4 weeks; sexual dysfunction common.
SNRIs: venlafaxine and duloxetine; monitor blood pressure.
Mirtazapine: sedating, weight gain; useful in depression with insomnia.
Bupropion: activating; contraindicated in epilepsy and eating disorders.
Tricyclics: cardiotoxic in overdose; anticholinergic effects.
MAOIs: tyramine restriction; hypertensive crisis.
Lithium: narrow therapeutic index; monitor levels and renal/thyroid function.
Clozapine: treatment-resistant schizophrenia; monitor FBC weekly for 18 weeks.
Psychotherapy and Psychosocial Interventions
CBT: effective for depression, anxiety, OCD, PTSD, and insomnia.
Psychodynamic therapy: explores unconscious conflict and transference.
IPT: focuses on role transitions, grief, disputes, and interpersonal deficits.
DBT: for borderline personality disorder and repeated self-harm.
Motivational interviewing: OARS; roll with resistance.
Family intervention: psychoeducation reduces relapse in schizophrenia.
Cognitive remediation: improves cognition in schizophrenia.
Therapeutic alliance: predicts outcome across therapies.
Risk Assessment, Emergency Psychiatry and Ethics/Professionalism
Suicide risk: ask directly; assess plan, intent, means, and protective factors.
Violence risk: history, substance use, psychosis, impulsivity, access to weapons.
Acute agitation: de-escalation first; rapid tranquillisation if needed; monitor vital signs.
Capacity: four abilities; act in best interests if lacking.
Confidentiality: disclose only with consent or legal requirement.
Informed consent: document discussion of risks, benefits, and alternatives.
Professional boundaries: avoid dual relationships; seek supervision.
Emergency detention: follow local mental health legislation; document rationale.
Psychotic Disorders
First-episode psychosis: early intervention improves outcomes; avoid high-dose antipsychotics.
Positive symptoms: hallucinations, delusions, disorganised thinking.
Negative symptoms: flat affect, alogia, avolition, anhedonia, asociality.
Treatment-resistant schizophrenia: clozapine after ≥2 failed antipsychotic trials.
Relapse prevention: continue antipsychotics for 1–2 years after first episode.
Catatonia: benzodiazepines and/or ECT.
NMS: rigidity, hyperthermia, autonomic instability, elevated CK; stop antipsychotic.
Physical health: monitor cardiovascular and metabolic risk.
Mood Disorders
Depression: ≥5 symptoms for ≥2 weeks; SIGECAPS.
Manic episode: ≥1 week; ≥3 symptoms (or ≥4 if irritable).
Hypomania: ≥4 days; no marked impairment.
Bipolar I: ≥1 manic episode; bipolar II: hypomania plus depression.
Rapid cycling: ≥4 episodes in 12 months.
Serotonin syndrome: altered mental status, autonomic instability, clonus.
Lithium: target 0.6–0.8 mmol/L; monitor renal and thyroid.
ECT: for severe depression with psychosis, catatonia, and food refusal.
Anxiety, Obsessive-Compulsive and Trauma-Related Disorders
Panic attack: abrupt surge peaking within minutes; ≥4 symptoms.
Agoraphobia: fear of ≥2 situations due to escape difficulty.
Social anxiety: fear of negative evaluation; ≥6 months.
OCD: obsessions and/or compulsions; >1 hour/day or impairment.
PTSD: trauma exposure plus intrusion, avoidance, negative mood, arousal; >1 month.
Acute stress disorder: 3 days to 1 month post-trauma.
First-line OCD: SSRIs at higher doses plus ERP.
First-line PTSD: trauma-focused CBT or EMDR; SSRIs.