ASCP PA study plan

Outline the major categories of surgical pathology specimens (e.g., GI, breast, skin, GU) and list the key diagnostic features for each

Describe the gross examination approach for common specimen types (e.g., margins, orientation, sectioning)

Explain the principles of frozen section and its indications/limitations

Identify the steps in tissue processing, embedding, and staining (H&E and special stains)

Compare and contrast benign versus malignant features in common tumors (e.g., breast, colon, skin)

Describe the staging principles (TNM) for major cancers and their prognostic significance

Explain the role of immunohistochemistry in diagnosis and classification of tumors

List common artifacts and their causes in surgical pathology

Summarize the handling of special specimens (e.g., lymph nodes, bone marrow, frozen sections)

Describe the autopsy procedure, including external examination, evisceration, and organ dissection

Explain the indications and legal aspects of autopsy (e.g., consent, reportable deaths)

Identify common postmortem changes and their significance

Outline the approach to cause of death determination and clinicopathologic correlation

List safety precautions and infection control measures during autopsy

Review and consolidate domain 1 concepts through mixed practice questions

Identify weak areas in surgical and autopsy pathology and create a targeted review plan

Describe the components of a quality management program in pathology (e.g., QC, QA, proficiency testing)

Explain the importance of accreditation and regulatory compliance (e.g., CAP, CLIA)

Define key quality indicators and metrics (e.g., turnaround time, error rates)

Describe the principles of laboratory safety, including chemical, biological, and fire safety

Explain the proper handling and disposal of hazardous materials (e.g., formalin, sharps, biohazard waste)

Outline the components of an exposure control plan and post-exposure prophylaxis

Identify the key elements of laboratory information systems and data integrity

Summarize the process of method validation and verification

Explain the principles of quality control for instruments and reagents (e.g., calibration, maintenance)

Describe the process of competency assessment for laboratory personnel

Outline the steps in root cause analysis and corrective action for laboratory errors

Summarize the requirements for specimen collection, handling, and rejection criteria

Describe the use of Lean and Six Sigma methodologies in laboratory process improvement

Review laboratory operations topics: staffing, workflow, and inventory management

Explain the importance of document control and record retention

Describe the process of internal and external audits

Outline the requirements for laboratory design and space planning

Summarize the key aspects of customer service and communication in the laboratory

Review all weak areas identified in previous weeks using flashcards and summary notes

Complete a full-length practice exam under timed conditions

Analyze practice exam results to identify remaining knowledge gaps

Create a final one-page quick-reference sheet for high-yield facts

Develop a test-day strategy including time management and question approach