RANZCP MCQ Exam flashcards
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- First-rank symptoms
- Schneiderian phenomena including audible thoughts, voices arguing or commenting, thought insertion, withdrawal or broadcast, made feelings, impulses or acts, and somatic passivity. Suggestive of schizophrenia but not diagnostic.
- Hypomania duration criterion
- Elevated or irritable mood with increased energy lasting at least four consecutive days, with unequivocal change, no marked impairment, no psychosis, and no need for hospitalisation.
- Serotonin syndrome features
- Neuromuscular hyperactivity with clonus, hyperreflexia, agitation, and hyperthermia, usually after serotonergic drugs. Clonus distinguishes it from neuroleptic malignant syndrome.
- Neuroleptic malignant syndrome
- Life-threatening reaction to dopamine antagonists with lead-pipe rigidity, hyperthermia, autonomic instability, raised creatine kinase, and leukocytosis, developing over one to three days.
- Overvalued idea
- A solitary, understandable belief pursued with unusual intensity that is less fixed than a delusion and partially responsive to reasoning, often seen in personality disorder.
- Four abilities of capacity
- Appelbaum and Grisso's framework: communicating a choice, understanding relevant information, appreciating the situation and its consequences, and reasoning about treatment options.
- Circumstantiality versus tangentiality
- Circumstantiality is overly detailed speech that eventually reaches the goal, whereas tangentiality drifts away and never answers the original question.
- MoCA versus MMSE
- Both score to 30; the Montreal Cognitive Assessment is more sensitive to mild cognitive impairment and executive dysfunction, while the Mini-Mental State Examination is more influenced by education.
- Clozapine monitoring requirements
- Regular full blood counts for neutropenia, plus cardiac monitoring for myocarditis and cardiomyopathy, in patients with schizophrenia resistant to at least two other antipsychotics.
- Lithium therapeutic range
- Maintenance serum levels of 0.6 to 0.8 mmol/L, sampled twelve hours after the dose, with monitoring of renal, thyroid, and calcium status and interaction with diuretics and NSAIDs.
- Tardive dyskinesia
- Involuntary orofacial choreoathetoid movements appearing after prolonged dopamine antagonist exposure, treated with vesicular monoamine transporter 2 inhibitors such as valbenazine.
- MAOI tyramine interaction
- Tyramine-rich foods with monoamine oxidase inhibitors can cause hypertensive crisis; washout periods of about two weeks are needed, and five weeks after fluoxetine.
- Exposure therapy mechanism
- Graded, repeated, prolonged contact with a feared stimulus without safety behaviours, allowing habituation and corrective learning that anxiety does not lead to catastrophe.
- Dialectical behaviour therapy modules
- Linehan's skills modules are mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness, targeting self-harm and therapy-interfering behaviour first.
- Transference and countertransference
- Transference is the patient's displaced feelings toward the therapist; countertransference is the therapist's emotional response, useful as information about the therapeutic relationship.
- Motivational interviewing stance
- A collaborative, evocative, autonomy-supportive style that explores ambivalence using open questions, affirmations, reflections, and summaries rather than confrontation.
- ADHD diagnostic thresholds
- At least six inattentive or hyperactive-impulsive symptoms, or five if aged seventeen or older, onset before twelve, across two settings with impairment.
- Tourette disorder criteria
- Multiple motor tics plus at least one vocal tic persisting more than one year, with onset before age eighteen; coprolalia occurs in only a minority.
- Refeeding syndrome
- Potentially fatal electrolyte shift, especially hypophosphataemia, during reintroduction of nutrition in malnourished patients, requiring cautious caloric advancement and electrolyte monitoring.
- Lewy body dementia sensitivity
- Severe neuroleptic sensitivity with marked extrapyramidal reactions; core features include fluctuating cognition, visual hallucinations, parkinsonism, and REM sleep behaviour disorder.
- Delirium core features
- Acute onset with fluctuating course, inattention, and altered consciousness, usually caused by infection, medication, pain, or metabolic disturbance in vulnerable older patients.
- Pseudodementia
- Cognitive impairment accompanying depression in older adults that improves when the mood disorder is treated, mimicking dementia but with different onset and effort.
- Acetylcholinesterase inhibitor indications
- Donepezil, rivastigmine, and galantamine are used for mild to moderate Alzheimer disease; memantine, an NMDA antagonist, is used in moderate to severe disease.
- Alcohol withdrawal timeline
- Tremor and anxiety from about six to twelve hours, hallucinations at twelve to twenty-four, seizures at twelve to forty-eight, and delirium tremens at forty-eight to ninety-six hours.
- Wernicke encephalopathy triad
- Ophthalmoplegia, ataxia, and confusion caused by thiamine deficiency, treated promptly with parenteral thiamine to prevent Korsakoff syndrome and death.
- Steroid-induced psychosis
- Dose-related affective or mixed psychotic symptoms appearing within days to weeks of corticosteroid use, managed by dose reduction and antipsychotics if required.
- M'Naghten rule
- A defence requiring a defect of reason from disease of the mind such that the accused did not know the nature and quality of the act or that it was wrong.
- Fitness to stand trial
- Ability to understand the charges and proceedings, instruct counsel, follow evidence, and appreciate the significance of the hearing; distinct from criminal responsibility.
- HCR-20 risk tool
- Structured professional judgement instrument for violence risk covering historical, clinical, and risk-management domains, used to inform rather than replace clinical decisions.
- Disulfiram contraindications
- Avoid in cardiac disease, psychosis, and pregnancy; it deters drinking by inhibiting aldehyde dehydrogenase, causing flushing, nausea, and hypotension with alcohol.
- Buprenorphine properties
- A partial mu-opioid agonist with high affinity and a ceiling effect on respiratory depression, used for opioid substitution with lower overdose risk than methadone.
- Korsakoff syndrome
- Anterograde amnesia with confabulation following untreated thiamine deficiency, caused by damage to mammillary bodies and anterior thalamic nuclei.