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Ideal body weight formula
For males: 50 kg + 2.3 kg per inch over 5 feet. For females: 45.5 kg + 2.3 kg per inch over 5 feet. Used for caloric and protein dosing when actual weight is unreliable.
Nitrogen balance equation
Nitrogen balance = (protein intake in grams / 6.25) minus (urine urea nitrogen in grams + 4 g). A positive value indicates anabolism; negative indicates catabolism.
Indirect calorimetry
Measures resting energy expenditure by analyzing oxygen consumption and carbon dioxide production. Respiratory quotient >1.0 suggests overfeeding; <0.7 suggests underfeeding or fat oxidation.
Albumin and prealbumin
Negative acute-phase reactants. Albumin half-life ~20 days; prealbumin ~2 days. Low levels reflect inflammation, not necessarily malnutrition, and are not reliable markers of nutritional status.
Enteral nutrition indications
Preferred when the gastrointestinal tract is functional but oral intake is inadequate. Examples include dysphagia, anorexia, critical illness, burns, and malabsorption with a working gut.
Enteral nutrition contraindications
Mechanical bowel obstruction, severe ischemic bowel, uncontrolled GI bleeding, high-output proximal fistula, severe malabsorption, and hemodynamic instability with gut hypoperfusion.
Parenteral nutrition indications
Short bowel syndrome, high-output fistula, severe pancreatitis with enteral intolerance, prolonged ileus, severe mucositis, and malnutrition when enteral nutrition is not feasible or contraindicated.
Gastric versus post-pyloric access
Gastric access (NG, PEG) is preferred when stomach and small bowel function. Post-pyloric (NJ, PEJ) is indicated for gastroparesis, severe GERD, pancreatitis, or high aspiration risk.
Peripheral parenteral nutrition limit
Peripheral PN osmolarity should not exceed 900 mOsm/L to avoid phlebitis. Central PN is required for higher osmolarity formulas and long-term therapy.
Refeeding syndrome risk factors
BMI <16, weight loss >15% in 3–6 months, negligible intake >10 days, low baseline electrolytes, and alcoholism. Start feeding low and monitor phosphate, potassium, and magnesium.
Standard polymeric formula
Enteral formula with intact protein and 1.0–1.2 kcal/mL. Requires normal digestion and absorption; used for most patients with a functioning GI tract.
Elemental formula
Contains free amino acids or peptides and is low-residue. Used for malabsorption, short bowel syndrome, pancreatic insufficiency, and when digestion or absorption is impaired.
Enteral feeding initiation
Start at 10–30 mL/hr and advance by 10–20 mL/hr every 4–8 hours to target over 24–48 hours. Check tube position before use and monitor tolerance.
Gastric residual volume
Routine checking is not required unless the patient is at high risk for aspiration or intolerance. Elevated residuals may prompt holding feeds and reassessment.
Head-of-bed elevation
Elevate the head of the bed 30–45 degrees during and after enteral feeding to reduce aspiration risk. Post-pyloric feeding further reduces aspiration risk.
Enteral formula hang time
Open-system formulas should hang no longer than 4 hours; feeding sets should be changed every 24 hours to reduce contamination and infection risk.
PN macronutrient caloric values
Dextrose provides 3.4 kcal/g; amino acids 4 kcal/g; 20% lipid emulsion provides 2.0 kcal/mL (10 kcal/g). These values are used to calculate total calories.
PN calcium-phosphate precipitation
Calcium and phosphate can precipitate in PN solutions. Use compatible salts, check for precipitate, and avoid adding calcium to phosphate-containing solutions without compatibility data.
Lipid emulsion limits
Limit lipid emulsions to ≤1 g/kg/day (or ≤2 g/kg/day in some settings). Monitor triglycerides, especially in hypertriglyceridemia or pancreatitis.
Cycled parenteral nutrition
PN infused over 12–16 hours rather than 24 hours. May reduce hepatic steatosis and improve mobility; taper to avoid rebound hypoglycemia.
PN compounding aseptic technique
Compounding requires a laminar flow hood, aseptic technique, order verification, labeling, and expiration dating. 2-in-1 and 3-in-1 admixtures have different stability considerations.
Catheter-related bloodstream infection
A serious complication of parenteral nutrition. Prevention includes strict aseptic technique, chlorhexidine skin prep, minimizing line accesses, and removing unnecessary catheters.
Hyperglycemia management in nutrition
Target glucose 140–180 mg/dL. Use insulin infusion or sliding scale and avoid overfeeding dextrose. Monitor glucose frequently during initiation and adjustment.
Enteral feeding diarrhea
Evaluate formula osmolality, infusion rate, medications (sorbitol, antibiotics), and infection such as C. difficile. Adjust rate, formula, or medications as indicated.
Hepatic complications of PN
Elevated transaminases, steatosis, and cholestasis. Strategies include cycling PN, limiting dextrose, and using fish-oil-based lipid emulsions.
Monitoring frequency in nutrition support
Daily weights and electrolytes during the acute phase; weekly labs once stable. Reassess nutritional goals regularly and adjust the regimen.
Diabetes nutrition support
Use consistent carbohydrate intake, monitor glucose, and adjust insulin. Enteral formulas with lower glycemic index may help control blood glucose.
Renal failure nutrition support
Pre-dialysis: restrict protein to 0.6–0.8 g/kg/day, potassium, phosphorus, and fluid. Dialysis patients need higher protein (1.2–1.5 g/kg/day).
Liver disease nutrition support
Provide adequate protein (1.2–1.5 g/kg/day) and calories. Do not restrict protein in encephalopathy; consider branched-chain amino acids.
Pancreatitis nutrition support
Enteral nutrition (nasojejunal) is preferred over parenteral. Start with a low-fat formula; use parenteral nutrition if enteral is not tolerated.
Short bowel syndrome diet
High-calorie, low-fat, low-oxalate diet with supplemental vitamins and minerals. Parenteral nutrition may be needed long-term depending on remaining bowel length.
Critical illness feeding
Start early enteral nutrition within 24–48 hours. Use trophic feeding if full feeds are not tolerated and avoid overfeeding to prevent complications.