BCPP flashcards

32 cards. Read the term and the definition here. The deck at the top of this page is optional.

PHQ-9 Severity Cutoffs

The Patient Health Questionnaire-9 scores 5-9 as mild, 10-14 moderate, 15-19 moderately severe, and 20-27 severe depression; a score of 10 or more suggests clinically significant major depression.

CIWA-Ar Treatment Threshold

The Clinical Institute Withdrawal Assessment for Alcohol-Revised scores 0-67; 8-15 indicates moderate withdrawal usually treated with benzodiazepines, and 16 or higher indicates severe withdrawal with seizure and delirium risk.

AIMS Abnormal Score

The Abnormal Involuntary Movement Scale rates 7 items from 0 to 4; a score of 2 or more on one item or 3 or more on two items is abnormal and warrants further tardive dyskinesia evaluation.

MDQ Positive Screen

The Mood Disorder Questionnaire screens for bipolar disorder and is positive when the patient endorses 7 or more of 13 symptoms, reports co-occurrence, and rates the resulting problem as moderate or serious.

C-SSRS High-Risk Items

The Columbia Suicide Severity Rating Scale grades ideation severity from 1 to 5; endorsement of active ideation with some intent (item 4) or with a plan (item 5) indicates high acute risk.

Lithium Level Sampling Time

Serum lithium is drawn as a trough 12 hours after the last dose; the maintenance range is 0.6-1.2 mEq/L, and levels above 1.5 mEq/L are associated with clinically significant toxicity.

Treatment-Resistant Depression Definition

Major depression is treatment resistant after failure of at least two adequate antidepressant trials, each using a therapeutic dose for 4-8 weeks with adherence verified.

Clozapine Indication in Schizophrenia

Clozapine is indicated for schizophrenia that has failed at least two different antipsychotics at adequate dose and duration, and for reducing recurrent suicidal behavior in schizophrenia or schizoaffective disorder.

First-Line Alcohol Use Disorder Drugs

Naltrexone (oral 50 mg daily or 380 mg intramuscular monthly) and acamprosate 666 mg three times daily are first-line for alcohol use disorder; disulfiram is second-line and requires abstinence and supervision.

OCD SSRI Trial Duration

Obsessive-compulsive disorder generally requires higher SSRI doses and a trial of 8-12 weeks before judging response, followed by at least 1-2 years of continued treatment after response.

Bipolar Antidepressant Monotherapy Risk

Antidepressant monotherapy is avoided in bipolar I disorder because of treatment-emergent mania and rapid cycling; lithium, valproate, or second-generation antipsychotics are preferred as mood stabilizers.

Buprenorphine First-Line for OUD

Buprenorphine-naloxone and methadone are first-line for opioid use disorder and both reduce mortality; buprenorphine's partial agonism produces a ceiling effect on respiratory depression.

Clozapine Neutrophil Monitoring Schedule

Absolute neutrophil count is checked weekly for 6 months, every 2 weeks for the next 6 months, then monthly for the duration of clozapine therapy; mild neutropenia requires twice-weekly monitoring.

Serotonin Syndrome Hunter Criteria

Serotonin syndrome is diagnosed when a serotonergic drug is used plus one of: spontaneous clonus, inducible clonus with agitation, ocular clonus with agitation, tremor with hyperreflexia, or hyperthermia with rigidity.

Neuroleptic Malignant Syndrome Features

Neuroleptic malignant syndrome presents with hyperthermia, lead-pipe rigidity, altered mental status, and autonomic instability with elevated creatine kinase; management is stopping the antipsychotic plus dantrolene or bromocriptine.

Citalopram QT Dose Limits

Citalopram is limited to 40 mg/day in adults because of dose-dependent QT prolongation, and to 20 mg/day in patients over 60 years, with hepatic impairment, or who are CYP2C19 poor metabolizers.

Valproate Teratogenicity Risk

First-trimester valproate exposure carries roughly a 1-2% risk of neural tube defects, plus higher risks of other malformations and reduced IQ, so it is avoided in pregnancy when alternatives exist.

Carbamazepine HLA-B*1502 Screening

Patients of Asian ancestry should be screened for HLA-B*1502 before starting carbamazepine because the allele strongly predicts Stevens-Johnson syndrome and toxic epidermal necrolysis.

SSRI Discontinuation Syndrome Risk

Abrupt SSRI or SNRI discontinuation can cause dizziness, paresthesias, insomnia, and irritability; risk is highest with paroxetine and venlafaxine, so tapering over weeks is recommended.

Aripiprazole Long-Acting Injection Overlap

Aripiprazole long-acting injectable requires 14 consecutive days of overlapping oral aripiprazole after the first injection because the depot takes about 2 weeks to reach therapeutic exposure.

Lurasidone Food Requirement

Lurasidone should be taken with at least 350 calories of food; dosing on an empty stomach reduces absorption by roughly half and can lower efficacy.

MAOI Tyramine-Restricted Diet

Patients taking monoamine oxidase inhibitors must avoid aged cheese, cured meats, tap beer, soy sauce, and fermented foods to prevent tyramine-induced hypertensive crisis.

Proportion of Days Covered

Proportion of days covered is a refill-based adherence measure; a value of 80% or higher is generally used as the threshold for adequate adherence in chronic disease.

SBAR Handoff Structure

SBAR is a structured communication tool standing for Situation, Background, Assessment, and Recommendation, used to convey clinical information concisely during handoffs and interprofessional escalation.

Collaborative Practice Agreement Definition

A collaborative practice agreement is a written protocol allowing a pharmacist to initiate, modify, or discontinue specified drug therapy under defined conditions and prescriber oversight; scope varies by state law.

42 CFR Part 2 Protections

42 CFR Part 2 is stricter than HIPAA for substance use disorder treatment records, requiring specific written patient consent before disclosure and prohibiting redisclosure without new consent.

BCPP Recertification Cycle

Board Certified Psychiatric Pharmacist credentials are awarded by the Board of Pharmacy Specialties and must be renewed every 7 years through examination or approved continuing education.

Just Culture Error Reporting

Just culture distinguishes human error, at-risk behavior, and reckless behavior so that systems are corrected and errors are reported without punitive response, improving medication safety.

Number Needed to Treat Formula

Number needed to treat equals 1 divided by the absolute risk reduction, where absolute risk reduction is the control event rate minus the treatment event rate.

Sensitivity Definition

Sensitivity is true positives divided by true positives plus false negatives; it is the proportion of people who have the disease and are correctly identified by the test.

Intention-to-Treat Principle

Intention-to-treat analysis includes all randomized participants in their assigned group regardless of adherence or crossover, preserving randomization and avoiding bias from selective dropout.

Odds Ratio Versus Risk Ratio

An odds ratio approximates the risk ratio only when the outcome is rare, generally under 10%; for common outcomes the odds ratio exaggerates the effect and the risk ratio should be used.