BSMMU Residency Phase-A study materials
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Postpartum Haemorrhage on a Resource-Limited Labour Ward

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Postpartum Haemorrhage on a Resource-Limited Labour Ward

A 27-year-old woman, gravida 3 para 2, delivers a 4.1 kg baby spontaneously after a 9-hour labour at a rural sub-district hospital. She received no uterotonic prophylaxis because the oxytocin cold chain had failed that morning. Thirty minutes after delivery, the placenta has been delivered complete but she is bleeding heavily. Estimated blood loss is now 900 mL and ongoing. Pulse 122/min, blood pressure 88/56 mmHg, respiratory rate 26/min, SpO2 94% on room air, and she is anxious and restless. The uterus is soft and boggy on palpation, located at the umbilicus. There is no perineal or vaginal laceration on inspection. The hospital has one unit of O-negative packed red cells, no formal blood bank, no intensive care unit, and one operating theatre with a general surgeon available. The referral facility is 90 minutes away by ambulance.

1. Establish the cause of haemorrhage and prioritise your first 15 minutes of management, explaining the sequence.

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Cause: This is primary postpartum haemorrhage due to uterine atony. Supporting features:

  • Soft, boggy uterus at the umbilicus - the classic sign of atony.
  • No genital tract trauma on inspection.
  • Placenta delivered complete - retained products are less likely, though not excluded without uterine exploration.
  • Risk factors: grand multiparity (para 2 with this being the third pregnancy), macrosomia (4.1 kg), prolonged labour, and absence of uterotonic prophylaxis because of the cold chain failure.

First 15 minutes - sequenced:

  1. Call for help and activate the massive haemorrhage pathway. Assign roles: one person for drugs, one for uterine massage, one for documentation and communication with the referral centre.
  2. Resuscitation: two large-bore intravenous cannulae, crystalloid, and start the O-negative unit early rather than waiting for laboratory confirmation - she is in class II–III shock with tachycardia, hypotension, and restlessness.
  3. Uterine massage and bimanual compression - mechanical control is immediate and requires no equipment.
  4. Uterotonics: oxytocin 10 IU intramuscularly (or slowly intravenously) followed by an infusion; ergometrine 0.5 mg intramuscularly if no hypertension; carboprost 250 micrograms intramuscularly every 15 minutes up to 8 doses if needed. Note that oxytocin may be unavailable given the cold chain issue - check stock and use alternatives.
  5. Empty the bladder with a catheter; a full bladder impairs uterine contraction.
  6. Tranexamic acid 1 g intravenously over 10 minutes as soon as possible, ideally within 3 hours of onset.
  7. Monitor pulse, blood pressure, urine output, and estimated loss; keep her warm.

Why this order: Airway and circulation come before definitive cause-directed therapy, but in PPH the cause-directed step (massage plus uterotonics) is itself resuscitative and must happen in parallel, not after fluid resuscitation.

2. Bleeding continues despite oxytocin, ergometrine, and uterine massage, with estimated loss now 1.8 L and blood pressure 78/48 mmHg. Decide between on-site surgical management and transfer, and justify your choice.

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Decision: proceed with on-site uterine-sparing surgical measures while simultaneously arranging transfer - do not delay intervention for transfer.

Reasoning:

  • She is now in class III–IV shock with a systolic pressure of 78 mmHg and continuing haemorrhage. A 90-minute ambulance journey with ongoing bleeding is likely to be fatal; the transfer itself is a risk, not a treatment.
  • The general surgeon and theatre are on site. The most immediately available definitive mechanical measures are intrauterine balloon tamponade (if a device or condom catheter is available) and bimanual compression, followed by laparotomy with uterine artery ligation or B-Lynch suture if tamponade fails.
  • Uterotonic escalation should continue in parallel: carboprost and, if available, misoprostol.
  • Blood products: the single O-negative unit is a holding measure; activate the referral centre's blood bank to send products and consider having the ambulance meet a blood courier en route if the local system allows.

Sequenced plan:

  1. Balloon tamponade as a bridge - it can control atony in a high proportion of cases and is reversible.
  2. If tamponade fails or is unavailable, proceed to laparotomy for uterine artery ligation or compression sutures, with the general surgeon and an assistant.
  3. Hysterectomy is the last resort if bleeding is uncontrollable and her life is at immediate risk - a general surgeon can perform it, and delay for a specialist is not justified in a dying patient.
  4. Transfer after stabilisation - once bleeding is controlled and the airway and circulation are secure, transfer for ongoing critical care.

Justification summary: The decision hinges on the principle that definitive haemostasis must not be deferred for transfer when the patient is unstable and surgical capability exists on site. Transfer is for escalation of care, not for primary control of a life-threatening bleed.

3. The family asks why the oxytocin was not given and whether this was negligence. How would you address this, and what system-level action should follow?

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Addressing the family:

  • Be honest and specific without assigning blame prematurely. Explain that a medicine (oxytocin) that helps the womb contract after birth was not available because the refrigerator keeping it cold had failed, and that this is being investigated.
  • Acknowledge the harm - she experienced a serious complication, and it is reasonable for the family to be concerned.
  • Explain what is being done now - describe the treatment she is receiving and the plan for transfer.
  • Avoid saying "it was nobody's fault" or promising outcomes. Avoid defensiveness and avoid speculation about individual culpability before a review.
  • Offer a route for formal concerns - patient liaison or complaints process - and document the conversation.

System-level action:

  1. Cold chain audit - review refrigerator temperature logs, power backup, and stock rotation for all temperature-sensitive medicines on the labour ward.
  2. Stock a heat-stable alternative - misoprostol or a heat-stable oxytocin formulation where available, so that a single cold chain failure does not eliminate prophylaxis.
  3. Protocol change - make uterotonic prophylaxis a checked, documented step in the delivery record, with a pre-delivery checklist confirming availability.
  4. Training and drills - run regular PPH drills including non-technical skills (role allocation, communication with referral centres).
  5. Incident reporting - log as a critical incident and feed into the hospital's clinical governance process, with learning shared across similar facilities.

Framing: The aim is system improvement and honesty with the family, not individual blame; a just-culture approach recognises that a failed cold chain is an organisational vulnerability rather than a single person's error.