SBFC Farmácia Clínica study guide
SBFC Farmácia Clínica · Work through your exam, one topic at a time.
The SBFC Farmácia Clínica certification, offered by the Sociedade Brasileira de Farmácia Clínica, is a professional credential for pharmacists in Brazil who want to demonstrate advanced competence in clinical pharmacy and pharmaceutical care. It is aimed at practitioners who already work in hospitals, clinics, primary care, or community settings and who take responsibility for medication therapy management, patient counseling, and interprofessional collaboration. The SBFC Farmácia Clínica study guide has 10 sections and about 2,371 words.
01Pharmaceutical Care and Clinical Pharmacy Practice
Pharmaceutical care is a patient-centred, outcomes-oriented practice in which the pharmacist accepts responsibility for the medication-related needs of the patient. Candidates must distinguish the pharmaceutical care process (assessment, identification of drug-related problems, care plan, monitoring) from the older product-focused dispensing role.
299 words, about 1 min02Pharmacotherapy of Cardiovascular and Metabolic Disorders
Candidates must master guideline-directed therapy for hypertension, heart failure, dyslipidaemia and diabetes. For hypertension , know first-line classes (thiazides, ACE inhibitors, ARBs, dihydropyridine calcium channel blockers) and that ACE inhibitors and ARBs are not combined.
272 words, about 1 min03Pharmacotherapy of Infectious Diseases and Antimicrobial Stewardship
Know the pharmacology of major antibiotic classes (beta-lactams, glycopeptides, aminoglycosides, fluoroquinolones, macrolides), their spectrum and key toxicities. Understand antimicrobial stewardship : right drug, right dose, right duration, de-escalation based on culture, and avoidance of unnecessary broad-spectrum agents.
250 words, about 1 min04Pharmacotherapy of Neurological and Psychiatric Disorders
Master the pharmacology of antidepressants (SSRIs, SNRIs, TCAs, MAOIs), antipsychotics (typical vs atypical), mood stabilisers (lithium, valproate, lamotrigine), antiepileptics and drugs for Parkinson disease. Know mechanisms, key adverse effects and monitoring.
224 words, about 1 min05Pharmacotherapy of Respiratory, Gastrointestinal and Renal Disorders
For asthma , know the stepwise approach: inhaled corticosteroid as the backbone, with long-acting beta-agonist combinations; SABA-only treatment is no longer preferred. For COPD , bronchodilators (LAMA, LABA) are central, with ICS reserved for exacerbation-prone patients with eosinophilic inflammation.
238 words, about 1 min06Oncology, Hematology and Immunosuppressive Therapy
Know the classes of antineoplastic agents (alkylating agents, antimetabolites, topoisomerase inhibitors, tubulin inhibitors, targeted therapies, immunotherapy) and their hallmark toxicities. Anthracyclines cause cardiotoxicity (monitor ejection fraction).
204 words, about 1 min07Pharmacokinetics, Pharmacodynamics and Therapeutic Drug Monitoring
Master the core pharmacokinetic parameters: absorption, bioavailability (F), volume of distribution (Vd), clearance (CL), half-life (t½) and their relationships (t½ ≈ 0.693 × Vd/CL). Understand zero- versus first-order kinetics, steady-state achievement (about 4–5 half-lives), loading doses versus maintenance doses, and the meaning of therapeutic index.
221 words, about 1 min08Pharmacogenomics and Precision Medicine
Understand how genetic variation in drug-metabolising enzymes (CYP2D6, CYP2C19, CYP2C9, TPMT, DPYD) and drug targets (e.g., HLA alleles) influences response and toxicity. Know the phenotype categories - poor, intermediate, extensive/normal, ultrarapid metabolisers - and how they alter prodrug activation versus active-drug clearance.
246 words, about 1 min09Medication Safety, Pharmacovigilance and Drug Interactions
Know the classification of adverse drug reactions (Type A augmented, dose-dependent; Type B bizarre, idiosyncratic), the difference between adverse events and adverse reactions, and the reporting system in Brazil (Notivisa, operated by Anvisa). Understand pharmacovigilance signals, under-reporting, and the importance of spontaneous reporting.
217 words, about 1 min10Pharmacy Law, Ethics and Professional Practice in Brazil
Know the Brazilian regulatory framework: the Lei Federal 5.991/1973 (pharmaceutical practice), Lei 9.782/1999 (Anvisa creation), RDC resolutions governing dispensing, and the Código de Ética Farmacêutica (Federal Pharmacy Council). Understand the role of the Conselho Federal de Farmácia (CFF) and regional councils (CRF), professional registration, and the prohibition of dispensing without a valid prescription for prescription-only medicines.
200 words, about 1 min