C-NPT study materials
C-NPT study resources

C-NPT key terms

C-NPT · Get comfortable with the vocabulary.

Pediatric Assessment Triangle (PAT)

A rapid, hands-off first impression of a sick infant or child built from three sides: appearance, work of breathing, and circulation to the skin. It guides how urgently stabilization must begin before vital signs are even measured.

Related: Primary Survey (ABCDE), Pre-transport Stabilization
Primary Survey (ABCDE)

A sequential bedside examination-airway, breathing, circulation, disability, exposure-that finds and fixes immediately life-threatening problems first. During transport it is repeated after every move, procedure, or change in the patient's condition.

Related: Pediatric Assessment Triangle (PAT), Pre-transport Stabilization
Pre-transport Stabilization

Completing essential interventions-airway control, vascular access, glucose, temperature, and drug therapy-at the referring hospital before departure, so the patient can tolerate the trip. Teams weigh this against the harm of delaying definitive care.

Related: Primary Survey (ABCDE), Neutral Thermal Environment, Structured Handoff (SBAR)
Apgar Score

A 0–2 score for heart rate, respiratory effort, muscle tone, reflex irritability, and color, assigned at one and five minutes after birth. It summarizes response to resuscitation but does not by itself diagnose asphyxia.

Related: Ballard Maturational Score, Primary Survey (ABCDE)
Oxygenation Index (OI)

Mean airway pressure multiplied by fraction of inspired oxygen, divided by arterial oxygen pressure, then multiplied by 100. Higher values mean worse gas exchange and help decide when to escalate to high-frequency ventilation or ECMO.

Related: High-Frequency Oscillatory Ventilation (HFOV), Positive End-Expiratory Pressure (PEEP)
Positive End-Expiratory Pressure (PEEP)

Positive pressure kept in the airways at the end of expiration that holds alveoli open, improves oxygenation, and prevents collapse. Excess PEEP can reduce venous return and blood pressure, so it is titrated against oxygenation and hemodynamics.

Related: High-Frequency Oscillatory Ventilation (HFOV), Air Leak Syndrome, Oxygenation Index (OI)
High-Frequency Oscillatory Ventilation (HFOV)

Ventilation using very small tidal volumes at a high rate around a constant distending pressure. Oxygenation depends mainly on mean airway pressure while carbon dioxide removal depends on amplitude and frequency; air trapping must be watched for.

Related: Oxygenation Index (OI), Air Leak Syndrome
End-Tidal Carbon Dioxide (EtCO2)

The carbon dioxide measured at the end of exhaled breath, displayed as a waveform and a number. It confirms tracheal tube placement, estimates arterial carbon dioxide, and falls sharply with poor pulmonary blood flow or cardiac arrest.

Related: Air Leak Syndrome
Air Leak Syndrome

Escape of gas from ruptured alveoli into pleural, mediastinal, or interstitial spaces, producing pneumothorax, pneumomediastinum, or pulmonary interstitial emphysema. Sudden desaturation with asymmetric breath sounds during positive-pressure ventilation calls for immediate needle decompression.

Related: Positive End-Expiratory Pressure (PEEP), High-Frequency Oscillatory Ventilation (HFOV), Barometric Pressure Effects of Altitude
Surfactant Replacement Therapy

Instillation of exogenous surfactant into the trachea of premature infants with respiratory distress syndrome to lower surface tension, recruit alveoli, and improve compliance. It is given early; transient desaturation, bradycardia, and tube obstruction can occur during dosing.

Related: Positive End-Expiratory Pressure (PEEP), Oxygenation Index (OI)
Ductal-Dependent Congenital Heart Disease

Heart lesions in which either pulmonary or systemic blood flow depends on a patent ductus arteriosus. Closure of the ductus causes rapid deterioration, so these infants need prostaglandin and careful management of oxygen and ventilation.

Related: Prostaglandin E1 (Alprostadil), Pre-ductal and Post-ductal Oxygen Saturation
Prostaglandin E1 (Alprostadil)

A continuous infusion that keeps the ductus arteriosus open when ductal-dependent heart disease is suspected. Apnea, hypotension, and fever are common, so the airway and blood pressure must be watched closely throughout transport.

Related: Ductal-Dependent Congenital Heart Disease, High-Alert Medication
Compensated Shock

Early shock in which blood pressure is still normal because tachycardia and vasoconstriction compensate, while perfusion to skin, kidneys, and brain is already poor. Delayed capillary refill and cool extremities are clues before hypotension appears.

Related: Neonatal Sepsis, Cerebral Perfusion Pressure
Pre-ductal and Post-ductal Oxygen Saturation

Pulse oximetry measured on the right hand and on a foot to compare saturation before and after the ductus arteriosus. A difference of more than a few percent suggests right-to-left shunting or persistent pulmonary hypertension.

Related: Ductal-Dependent Congenital Heart Disease, Hypercyanotic (Tet) Spell
Hypercyanotic (Tet) Spell

A sudden worsening of cyanosis and distress in a child with tetralogy of Fallot, driven by increased right-to-left shunting. Treatment includes calming, knee-chest position, oxygen, fluid, and vasopressor or beta-blocker therapy.

Related: Ductal-Dependent Congenital Heart Disease, Prostaglandin E1 (Alprostadil)
Pediatric Glasgow Coma Scale

An age-adjusted scale scoring eye opening, verbal response, and best motor response in infants and children. Serial scores track neurological deterioration and help decide about airway protection and destination.

Related: Cerebral Perfusion Pressure, Neonatal Seizure
Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy

Controlled cooling to roughly 33–34 °C, begun within six hours of birth, for moderate to severe hypoxic-ischemic encephalopathy. It reduces death and disability but demands precise temperature control and attention to bradycardia, clotting, and glucose.

Related: Neonatal Seizure, Neutral Thermal Environment
Neonatal Seizure

Abnormal electrical brain activity in a newborn that may appear as subtle eye, mouth, or limb movements, apnea, or rhythmic cycling rather than classic convulsions. Confirmation often requires electroencephalography, and treatment addresses the underlying cause as well as the seizure.

Related: Pediatric Glasgow Coma Scale, Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy
Ballard Maturational Score

A physical and neurological examination that estimates gestational age in newborns using features such as skin, ear cartilage, breast tissue, and posture. It helps teams anticipate respiratory distress, hypoglycemia, and feeding difficulty during transport.

Related: Apgar Score, Neutral Thermal Environment
Cerebral Perfusion Pressure

Mean arterial pressure minus intracranial pressure. It is the driving pressure for blood flow to the brain, so hypotension or raised intracranial pressure in a head-injured child threatens cerebral oxygenation.

Related: Pediatric Glasgow Coma Scale, Compensated Shock
Holliday-Segar Maintenance Fluid

A method of estimating daily maintenance fluid from body weight: 100 mL/kg for the first 10 kg, 50 mL/kg for the next 10, and 20 mL/kg thereafter. It guides hourly rates and is adjusted for illness, losses, and glucose needs.

Related: Glucose Infusion Rate (GIR), Gastric Decompression
Glucose Infusion Rate (GIR)

The milligrams of glucose delivered per kilogram per minute, calculated from dextrose concentration, infusion rate, and weight. It is used to titrate fluids for hypoglycemia or hyperglycemia in neonates, whose glycogen stores are limited.

Related: Holliday-Segar Maintenance Fluid, Neonatal Pharmacokinetics
Necrotizing Enterocolitis (NEC)

An inflammatory bowel injury seen mostly in premature infants that causes feeding intolerance, abdominal distension, bloody stools, and lethargy. Transport care includes stopping feeds, decompressing the stomach, giving antibiotics and fluids, and watching for perforation and shock.

Related: Gastric Decompression, Neonatal Sepsis
Gastric Decompression

Placement of a nasogastric or orogastric tube to remove swallowed air and fluid, relieving distension that can splint the diaphragm and impair ventilation. It is routine in ventilated infants, bowel obstruction, and before air transport.

Related: Necrotizing Enterocolitis (NEC), Barometric Pressure Effects of Altitude
Weight-Based Dosing

Calculating every medication dose from the patient's weight in kilograms, using a measured or recently documented weight. Because neonatal and pediatric weights vary widely, errors in weight, units, or decimal placement are common and dangerous.

Related: High-Alert Medication, Neonatal Pharmacokinetics
High-Alert Medication

A drug carrying a heightened risk of serious harm when used incorrectly, such as vasopressors, insulin, opioids, concentrated electrolytes, and anticoagulants. These require independent double checks, standardized concentrations, and clear labeling during transport.

Related: Weight-Based Dosing, Y-Site Compatibility, Prostaglandin E1 (Alprostadil)
Y-Site Compatibility

Whether two medications or solutions can safely share one intravenous line through a Y-connector without precipitation or inactivation. Compatibility must be verified before drugs are infused together in a patient with limited vascular access.

Related: High-Alert Medication, Weight-Based Dosing
Neonatal Pharmacokinetics

How drug absorption, distribution, metabolism, and elimination differ in newborns, who have more body water, lower protein binding, and immature liver and kidney clearance. These differences change dosing intervals and raise the risk of toxicity.

Related: Weight-Based Dosing, High-Alert Medication
Neutral Thermal Environment

The surrounding temperature range in which a baby uses the least oxygen and energy to keep a normal body temperature. Maintaining it prevents cold stress, hypoglycemia, and acidosis during assessment and transport.

Related: Evaporative Heat Loss, Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy
Evaporative Heat Loss

Heat lost when water evaporates from wet skin or a wet surface, greatest in premature infants because their skin is thin and permeable. It is reduced by drying the infant, warming and humidifying gases, and covering the body.

Related: Neutral Thermal Environment, Pre-transport Stabilization
Neonatal Sepsis

A systemic bacterial infection in the first month of life, called early onset when acquired around birth and late onset when acquired afterward. Signs are subtle-temperature instability, poor feeding, apnea, shock-so antibiotics are often started empirically.

Related: Compensated Shock, Necrotizing Enterocolitis (NEC)
Barometric Pressure Effects of Altitude

The fall in atmospheric pressure as altitude rises, which lets gas in trapped spaces, endotracheal cuffs, and air-filled equipment expand. Teams adjust cuff pressure, vent trapped air, and anticipate changes in oxygen delivery during air transport.

Related: Air Leak Syndrome, Oxygen Cylinder Duration Calculation, Gastric Decompression
Oxygen Cylinder Duration Calculation

Estimated by dividing the cylinder's remaining gas volume in liters by the flow rate in liters per minute. Knowing this for each cylinder and each leg of the trip prevents running out of oxygen in flight or en route.

Related: Barometric Pressure Effects of Altitude, Pre-Departure Checklist
Child Passenger Restraint

Approved seats or harness systems that hold the infant or child securely in an ambulance or aircraft, chosen for weight, age, and medical equipment. Unsecured children and equipment become projectiles in a crash or sudden maneuver.

Related: Pre-Departure Checklist, Landing Zone Safety
Pre-Departure Checklist

A standardized review of airway equipment, medications, oxygen supply, battery charge, suction, and patient stability completed before leaving the referring site. It reduces omissions when teams are rushed or distracted.

Related: Oxygen Cylinder Duration Calculation, Structured Handoff (SBAR)
Landing Zone Safety

Selecting and controlling a clear, obstacle-free area for helicopter takeoff and landing, marking hazards, keeping bystanders back, and securing loose objects. Ground crews must never approach the aircraft unless escorted by flight personnel.

Related: Child Passenger Restraint, Pre-Departure Checklist
Structured Handoff (SBAR)

A handoff format-situation, background, assessment, recommendation-used to transfer information between teams. It reduces omissions and misunderstandings when care passes from referring staff to transport crew or to the receiving unit.

Related: Pre-transport Stabilization, Medical Direction (Transport)
Family-Centered Care

Practice that treats parents as partners, explaining what is happening and involving them in decisions within the limits of an emergency. It reduces parental distress and supports the child's coping during transport.

Related: Structured Handoff (SBAR), EMTALA
EMTALA

A federal law requiring hospitals with emergency departments to screen and stabilize anyone with an emergency condition before transfer, and to transfer only when the benefit outweighs the risk and a receiving facility accepts.

Related: Medical Direction (Transport), Family-Centered Care
Medical Direction (Transport)

Physician oversight of the transport team's protocols, scope of practice, and quality review, available for online consultation and offline guidance. It keeps decisions made en route within agreed standards and preserves accountability.

Related: EMTALA, Structured Handoff (SBAR)