ca-cna-critical-care-pediatrics flashcards
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- Pediatric Glasgow Coma Scale
- Age-specific scoring from 3 to 15 using eye, verbal, and motor components; children under 5 use different verbal and motor anchors than adults, so the scale version must be documented.
- Cushing response
- Hypertension with bradycardia and irregular respirations seen with raised intracranial pressure; it is a late and ominous sign of impending herniation requiring immediate intervention.
- Decerebrate posturing
- Extension of all four limbs with internal rotation after a painful stimulus; it localizes at or below the red nucleus and indicates a worse prognosis than decorticate posturing.
- Cerebral perfusion pressure
- Mean arterial pressure minus intracranial pressure; age-specific targets are maintained to preserve cerebral blood flow, generally aiming for at least 40 to 50 mmHg in young children.
- Monro-Kellie doctrine
- The skull has a fixed volume containing brain, blood, and cerebrospinal fluid; an increase in one compartment must be offset by a decrease in another or intracranial pressure rises.
- External ventricular drain care
- The drain measures intracranial pressure and drains cerebrospinal fluid; the transducer is leveled to the tragus or foramen magnum and strict sterile technique prevents infection.
- Status epilepticus definition
- Continuous seizure activity lasting five minutes or more, or recurrent seizures without return to baseline between events; treatment with a benzodiazepine begins at five minutes.
- Refractory status epilepticus
- Seizures that persist despite two appropriately dosed antiseizure medications; management requires continuous anesthetic infusion with continuous EEG monitoring, usually in an intensive care unit.
- Febrile status epilepticus
- A prolonged seizure with fever in a child six months to five years without central nervous system infection; the risk of later epilepsy is low but evaluation must exclude meningitis.
- Neonatal seizure presentation
- Often subtle with automatisms, apnea, or cycling movements and frequently electrographic only; phenobarbital is first-line therapy and continuous EEG is needed for diagnosis.
- Severe pediatric traumatic brain injury
- Post-resuscitation Glasgow Coma Scale of 3 to 8; management targets normoxia, normocapnia, normotension, normothermia, and normonatremia while avoiding hypotension.
- Hyperventilation in herniation
- Brief reduction of PaCO2 to 30 to 35 mmHg causes cerebral vasoconstriction and lowers intracranial pressure; it is reserved for acute herniation because prolonged hypocapnia causes ischemia.
- Neurogenic shock
- Hypotension with bradycardia from loss of sympathetic tone after spinal cord injury; treatment is volume resuscitation plus vasopressors such as norepinephrine or phenylephrine.
- Autonomic dysreflexia
- Hypertension, bradycardia, headache, and flushing triggered by bladder or bowel distension in lesions at T6 or above; treatment is removing the stimulus and giving antihypertensives.
- Pediatric arterial ischemic stroke
- Acute focal neurologic deficit from arterial occlusion, associated with arteriopathy, cardiac disease, sickle cell disease, and prothrombotic states; MRI with diffusion-weighted imaging is preferred for diagnosis.
- Cerebral venous sinus thrombosis
- Thrombosis of cerebral veins or sinuses presenting with headache, papilledema, seizures, and focal deficits; anticoagulation with low-molecular-weight heparin is standard even with hemorrhagic infarction.
- Posterior reversible encephalopathy syndrome
- Headache, seizures, visual changes, and hypertension with posterior white matter edema on imaging; treatment is blood pressure control and stopping the triggering agent.
- Cerebral salt wasting versus SIADH
- Both cause hyponatremia after brain injury; cerebral salt wasting is hypovolemic from renal sodium loss, while SIADH is euvolemic from inappropriate water retention.
- Bacterial meningitis empiric therapy
- Vancomycin plus ceftriaxone or cefotaxime; add ampicillin for neonates and Listeria risk, and give dexamethasone before or with the first antibiotic dose when Haemophilus influenzae type b is suspected.
- Lumbar puncture contraindications
- Focal neurologic deficit, papilledema, altered consciousness, seizures, hemodynamic instability, or coagulopathy; antibiotics and blood cultures should not be delayed when lumbar puncture is deferred.
- Herpes simplex encephalitis
- Fever, seizures, and temporal lobe findings caused by herpes simplex virus; intravenous acyclovir is required and should be started empirically when suspected.
- Neonatal meningitis pathogens
- Group B Streptococcus, Escherichia coli, and Listeria monocytogenes; presentation is often subtle with poor feeding, temperature instability, and apnea rather than classic meningismus.
- Guillain-Barre syndrome
- Ascending symmetric weakness with areflexia and elevated cerebrospinal fluid protein with normal cell count; treatment is intravenous immunoglobulin or plasma exchange with respiratory monitoring.
- Guillain-Barre respiratory failure
- Predicted by vital capacity below 15 to 20 mL/kg, inability to count to 20 in one breath, or bulbar weakness; serial vital capacity and negative inspiratory force guide intubation.
- Myasthenic crisis
- Worsening bulbar and respiratory weakness from myasthenia gravis; treat with acetylcholinesterase inhibitors, corticosteroids, intravenous immunoglobulin, or plasma exchange and avoid aminoglycosides and magnesium.
- Botulism in children
- Descending symmetric flaccid paralysis with ptosis and bulbar weakness caused by botulinum toxin; treatment is botulinum antitoxin plus supportive ventilation and secretion management.
- Propofol infusion syndrome
- Metabolic acidosis, rhabdomyolysis, hyperkalemia, and cardiac failure from prolonged high-dose propofol infusion; continuous propofol sedation is avoided in children.
- Dexmedetomidine effects
- Provides sedation and analgesia without significant respiratory depression but causes bradycardia and hypotension; it is unsuitable for deep sedation requiring airway protection.
- Opioid reversal with naloxone
- Naloxone reverses opioid-induced respiratory depression but may precipitate withdrawal and seizures in dependent patients; titrate small doses and monitor for renarcotization.
- Continuous EEG indications
- Unexplained altered mental status, refractory status epilepticus, and titration of anesthetic infusions; it detects nonconvulsive seizures and burst suppression not seen on clinical exam.
- Near-infrared spectroscopy
- Noninvasive monitoring of regional cerebral oxygen saturation; trends rather than absolute values guide interpretation and should be correlated with intracranial pressure and clinical findings.
- Family-centered care in neurocritical care
- Includes parents in rounds, explains findings in plain language, and supports family presence during resuscitation when safe; older children should be asked for assent to treatment.