ABGC Certification Examination (CGC credential) case studies
CGC · Put your knowledge to work in context.
The CGC credential is a certification mark awarded by the American Board of Genetic Counseling (ABGC) to individuals who pass the ABGC Examination. ABGC describes its work as promoting high standards in genetic counseling certification, and the CGC mark may only be used by someone holding a valid, current credential conferred after passing that exam. The CGC case studies are 5 cases and about 3,132 words.
1Atypical 22q11.2 Finding on Cell-Free DNA at 13 Weeks
A 34-year-old G2P1 at 12 weeks 6 days undergoes cell-free DNA screening because of maternal age. The report states low risk for trisomies 21, 18, and 13 but flags an atypical finding suggestive of a 22q11.2 deletion; fetal fraction is 8%.
630 words, about 3 min2Huntington Disease Predictive Testing When the Mother Objects
Lena, 26, requests predictive testing for Huntington disease. Her maternal aunt died at 58 with HD, and her mother, now 50, is asymptomatic and has repeatedly said she does not want testing because 'what I don't know won't hurt me.' Lena's mother also asked the clinic not to test Lena because a positive result would tell the mother she carries the expansion.
650 words, about 3 min3Parental Request for BRCA1 Testing in a 9-Year-Old
The parents of a 9-year-old girl request BRCA1 testing because the girl's mother carries a pathogenic BRCA1 variant and the mother's sister died of ovarian cancer at 44. The parents say they want to 'prepare her' and start breast surveillance early; they also worry about a future insurer.
627 words, about 3 min4BRCA2 Variant of Uncertain Significance Before Breast Surgery
Mark, 45, has unilateral stage II, ER-positive breast cancer and a 12-gene panel showing a BRCA2 variant classified as a variant of uncertain significance. He has no family history of breast, ovarian, pancreatic, or prostate cancer.
603 words, about 3 min5First-Cousin Couple Requesting 'Testing for Everything'
A 29-year-old woman at 10 weeks' gestation presents with her 31-year-old husband; they are first cousins and both grew up in a community with frequent cousin marriage. Neither has a known genetic condition, and their 2-year-old daughter is healthy.
622 words, about 3 min