CLEP Biology study materials
CLEP Biology study resources

CLEP Biology study plan

CLEP Biology · Give each week a clear focus.

8 weeks · About 6 hours per week

Week 1

Molecular and Cellular Biology

  • Define the four major macromolecule classes and list the monomers and bond types for each

  • Diagram the structure and function of the plasma membrane, including phospholipid bilayer and embedded proteins

  • Compare prokaryotic and eukaryotic cell structures by listing three shared and three distinguishing features

  • Label the major organelles and state one primary function for each

Your checkpoint

A one-page hand-drawn cell diagram with at least 10 labeled structures and a matching function list

Week 2

Molecular and Cellular Biology

  • Describe enzyme structure, substrate specificity, and the effects of temperature and pH on activity

  • Trace the inputs and outputs of glycolysis, the Krebs cycle, and oxidative phosphorylation

  • Explain how ATP is generated via substrate-level phosphorylation and chemiosmosis

  • Distinguish aerobic from anaerobic respiration and identify fermentation end products

Your checkpoint

A completed pathway map of cellular respiration showing net ATP, NADH, and FADH2 counts per glucose

Week 3

Molecular and Cellular Biology

  • Summarize the phases of mitosis and identify the key events of each

  • Compare mitosis and meiosis by chromosome number and daughter cell outcomes

  • Describe the steps of DNA replication and the roles of helicase, polymerase, and ligase

  • Explain transcription and translation, including mRNA processing and codon-anticodon pairing

Your checkpoint

A 15-question self-written quiz on cell division and gene expression, scored with corrections

Week 4

Molecular and Cellular Biology & Organismal Biology

  • Predict inheritance ratios using Punnett squares for monohybrid and dihybrid crosses

  • Distinguish Mendelian, codominant, and sex-linked inheritance patterns

  • Identify the structures and functions of the major plant and animal tissue types

  • Describe the roles of the major organ systems in maintaining homeostasis

Your checkpoint

A genetics problem set of 10 crosses solved with shown work and stated ratios

Week 5

Organismal Biology

  • Trace the path of blood through the mammalian heart and circulatory system

  • Explain gas exchange in lungs and the mechanics of breathing

  • Compare the nervous and endocrine systems by signal speed, duration, and transmission route

  • Describe the role of the kidney in osmoregulation and blood pH balance

Your checkpoint

A labeled diagram of the heart, lung, and nephron with a written explanation of blood flow and filtration

Week 6

Organismal Biology

  • Outline the stages of embryonic development from fertilization through gastrulation

  • Explain how plant roots, stems, and leaves acquire and transport water and nutrients

  • Compare phototropism, gravitropism, and photoperiodism as plant responses

  • Describe the life cycles of mosses, ferns, and flowering plants, noting alternation of generations

Your checkpoint

A comparison chart of plant and animal development across at least five stages

Week 7

Population Biology

  • Calculate population growth using exponential and logistic models given r, K, and N

  • Interpret survivorship curves and life tables to classify reproductive strategies

  • Explain competitive exclusion, niche partitioning, and predator-prey dynamics

  • Trace energy flow through trophic levels and calculate ecological efficiency

Your checkpoint

A worked problem set of 8 population and community calculations with final answers and units

Week 8

Population Biology & Molecular and Cellular Biology & Organismal Biology

  • Describe the major biogeochemical cycles and human impacts on each

  • Distinguish primary from secondary succession and identify pioneer species

  • Review weakest subtopics from prior weeks using missed-question logs

  • Complete two timed full-length practice sections and analyze error patterns by domain

Your checkpoint

A written error analysis identifying the three weakest subtopics and a targeted review checklist

Milestones

Week 2: Score at least 80% on a self-made 20-question cellular respiration and enzyme quiz

Week 4: Correctly solve 8 of 10 genetics problems without notes

Week 6: Explain blood flow and nephron function aloud in under 5 minutes without reference

Week 8: Achieve at least 70% on each of two timed full-length practice sections with documented error review