CNIM study materials
CNIM study resources

CNIM key terms

CNIM · Get comfortable with the vocabulary.

Resting membrane potential

The steady voltage difference across a neuron's membrane at rest, roughly −70 mV inside relative to outside, maintained mainly by potassium leak channels and the sodium-potassium pump.

Related: Action potential, Neuromuscular junction
Action potential

A rapid, all-or-none reversal of membrane voltage that travels along an axon once depolarization reaches threshold, carrying information from one part of a neuron to another.

Related: Resting membrane potential, Neuromuscular junction
Neuromuscular junction

The synapse where a motor nerve terminal releases acetylcholine onto nicotinic receptors of a muscle fiber, producing an endplate potential that can trigger contraction.

Related: Motor unit action potential, Train-of-four
Upper motor neuron

A neuron whose cell body sits in motor cortex or brainstem and whose axon descends in the corticospinal or corticobulbar tract to influence lower motor neurons.

Related: Lower motor neuron, Corticospinal tract
Lower motor neuron

A neuron with its cell body in the spinal anterior horn or a cranial nerve nucleus whose axon directly innervates skeletal muscle; injury produces weakness, atrophy, and fasciculations.

Related: Upper motor neuron, Motor unit action potential
Dermatome

The strip of skin supplied by sensory fibers from a single spinal nerve root, used to select stimulation and recording sites and to interpret root-level changes.

Related: Myotome, Somatosensory evoked potential
Myotome

The group of muscles innervated by one spinal nerve root; myotomal mapping determines which muscles to record when monitoring motor pathways at a given surgical level.

Related: Dermatome, Transcranial electrical stimulation
Dorsal column–medial lemniscus pathway

The ascending system carrying fine touch, vibration, and joint position sense through the dorsal columns and medial lemniscus to somatosensory cortex; it generates the signals recorded in SSEPs.

Related: Somatosensory evoked potential, Far-field potential
Corticospinal tract

The descending motor pathway running from cortical motor neurons through the internal capsule, brainstem, and pyramidal decussation to the spinal cord; it is the target of motor evoked potential monitoring.

Related: Upper motor neuron, D-wave
Differential amplifier

An amplifier that magnifies the voltage difference between two active inputs while rejecting voltage common to both, improving the recorded neural signal relative to background noise.

Related: Common mode rejection ratio, Impedance
Common mode rejection ratio

A measure of how effectively a differential amplifier cancels signals present equally at both inputs; higher values mean better suppression of interference such as 60 Hz line noise.

Related: Differential amplifier, 60 Hz interference
Far-field potential

A response recorded far from its generator after spread by volume conduction; it is typically low in amplitude and broad in shape, as with subcortical and scalp SSEP components.

Related: Somatosensory evoked potential, Dorsal column–medial lemniscus pathway
Impedance

The opposition to alternating current at the electrode-skin interface, expressed in ohms; high or unequal impedance increases noise and artifact in evoked potential recordings.

Related: Differential amplifier, 60 Hz interference
Filter settings

Low- and high-frequency limits that determine which frequencies a recording channel passes; overly narrow settings reduce noise but can distort or erase genuine evoked potential components.

Related: Far-field potential, Baseline recording
Minimum alveolar concentration

The alveolar concentration of an inhaled anesthetic at which half of patients do not move to a standard surgical stimulus; it indexes potency and predicts dose-dependent suppression of evoked potentials.

Related: Nitrous oxide, Anesthetic fade
Total intravenous anesthesia

Anesthesia maintained with intravenous agents such as propofol and opioids instead of inhaled gases; it is preferred for motor evoked potential monitoring because cortical responses are suppressed less.

Related: Minimum alveolar concentration, Anesthetic fade
Train-of-four

Four supramaximal stimuli delivered to a motor nerve at 2 Hz to quantify neuromuscular blockade; even partial blockade can markedly reduce motor evoked potential amplitude.

Related: Neuromuscular junction, Transcranial electrical stimulation
Anesthetic fade

A gradual decline in evoked potential amplitude over hours of otherwise stable anesthesia from cumulative drug effects and other factors; it must be told apart from a new surgical injury.

Related: Minimum alveolar concentration, Warning criterion
Cerebral autoregulation

The capacity of cerebral arterioles to adjust caliber and hold cerebral blood flow nearly constant across a range of mean arterial pressures; when impaired, hypotension raises ischemic risk.

Related: Electroencephalography, Anesthetic fade
Nitrous oxide

An inhaled anesthetic and analgesic that suppresses cortical motor evoked potentials and, when combined with volatile agents, can substantially reduce monitoring signals.

Related: Minimum alveolar concentration, Transcranial electrical stimulation
Ketamine

An NMDA-receptor antagonist used for analgesia and sedation that tends to preserve or increase motor and somatosensory evoked potential amplitudes, making it useful during total intravenous anesthesia.

Related: Total intravenous anesthesia, Transcranial electrical stimulation
Somatosensory evoked potential

Averaged cortical and subcortical responses to electrical stimulation of a peripheral nerve, used to monitor the dorsal column–medial lemniscus pathway during surgery.

Related: Dermatome, Far-field potential
Transcranial electrical stimulation

Delivery of brief high-voltage pulses through scalp electrodes to excite motor cortex and elicit motor evoked potentials, usually recorded from limb muscles.

Related: D-wave, Bite block
D-wave

A direct descending volley recorded from the spinal cord after transcranial stimulation; it reflects corticospinal tract integrity and is relatively resistant to anesthetic suppression.

Related: Transcranial electrical stimulation, Corticospinal tract
Brainstem auditory evoked potential

A series of short-latency waves generated by the auditory nerve and brainstem pathways within about 10 milliseconds of a click stimulus, used to monitor the eighth nerve and brainstem.

Related: Baseline recording, Warning criterion
Spontaneous electromyography

Continuous recording of muscle electrical activity without deliberate stimulation; bursts or trains suggest mechanical or thermal nerve irritation and warn of impending injury.

Related: Triggered electromyography, Motor unit action potential
Triggered electromyography

Electrical stimulation of tissue or hardware, such as a pedicle screw, while recording muscle responses to determine whether neural structures lie close to the stimulating probe.

Related: Spontaneous electromyography, Warning criterion
Electroencephalography

Recording of summed cortical postsynaptic activity from scalp electrodes, used intraoperatively to assess cortical function, depth of anesthesia, and developing cerebral ischemia.

Related: Cerebral autoregulation, International 10-20 system
Phase reversal

A shift in polarity of a recorded potential between adjacent electrodes overlying a generator, used during cortical mapping to identify the sensorimotor region.

Related: Electroencephalography, International 10-20 system
Motor unit action potential

The waveform produced by near-simultaneous discharge of the muscle fibers belonging to one motor unit, as recorded with a needle or surface electrode.

Related: Spontaneous electromyography, Neuromuscular junction
International 10-20 system

A standardized scheme for placing scalp electrodes at measured fractions between skull landmarks, making recording sites reproducible and comparable across patients and sessions.

Related: Electroencephalography, Impedance
Bite block

A soft device inserted between the teeth during transcranial electrical stimulation to protect the tongue and teeth from injury caused by forceful masseter contraction.

Related: Transcranial electrical stimulation
60 Hz interference

Electrical noise picked up from power lines and nearby equipment; it appears as a regular sine wave and is reduced by low impedance, twisted leads, and proper grounding.

Related: Impedance, Common mode rejection ratio
Baseline recording

The reference evoked potential or EMG data collected after anesthesia and positioning but before the surgical step at risk, against which later changes are judged.

Related: Warning criterion, Anesthetic fade
Warning criterion

A predefined amount of change, such as a 50 percent amplitude drop in somatosensory evoked potentials, that triggers notification of the surgeon so corrective action can be taken.

Related: Baseline recording, Closed-loop communication
Intraoperative monitoring record

The written and electronic documentation of baseline and serial recordings, stimulation parameters, anesthetic events, alerts raised, and actions taken during a monitored case.

Related: Baseline recording, Scope of practice
Closed-loop communication

A communication style in which the sender states a message, the receiver repeats it back, and the sender confirms, reducing misunderstanding during urgent intraoperative alerts.

Related: Warning criterion, Intraoperative monitoring record
Scope of practice

The boundaries of what a monitoring technologist or professional may independently do, including who interprets data and who communicates findings to the surgical team.

Related: Intraoperative monitoring record, Closed-loop communication