COMLEX Level 3 flashcards
COMLEX Level 3 · Build recall with a focused review session.
32 cards. Read the term and the definition here. The deck at the top of this page is optional.
- Somatic dysfunction definition
- Impaired or altered function of related components of the somatic system (skeletal, arthrodial, myofascial) diagnosed by TART: tissue texture change, asymmetry, restriction of motion, and tenderness.
- Direct versus indirect technique
- Direct technique engages the restrictive barrier and moves toward it (HVLA, muscle energy). Indirect technique moves the region away from the barrier into ease (counterstrain, functional, balanced ligamentous tension).
- HVLA contraindications
- Avoid high-velocity low-amplitude thrust with osteomyelitis, metastatic bone disease, fracture, severe osteoporosis, and unstable cervical spine. Caution with anticoagulation and conditions causing atlantoaxial instability such as Down syndrome.
- Counterstrain technique parameters
- Position the tender point into a position of ease until tenderness decreases at least 70 percent, hold about 90 seconds, then slowly return to neutral and reassess the point.
- Lymphatic pump contraindications
- Avoid lymphatic pump techniques in acute infection with fever, deep vein thrombosis, and decompensated heart failure, because they increase venous and lymphatic return to the central circulation.
- Cranial rhythmic impulse rate
- The primary respiratory mechanism is described as having a normal cranial rhythmic impulse of approximately 10 to 14 cycles per minute in adults, assessed by trained palpation.
- Suture removal timing
- Typical removal: face 4 to 5 days, scalp and trunk 7 to 10 days, extremities 10 to 14 days, and over joints about 14 days. Prolong when healing is impaired.
- Septic joint synovial fluid
- Septic synovial fluid typically shows more than 50,000 white cells per microliter with more than 75 percent neutrophils, plus positive Gram stain or culture. Avoid aspiration through overlying cellulitis.
- Anaphylaxis first-line treatment
- Give intramuscular epinephrine 0.3 to 0.5 mg of 1:1000 solution into the anterolateral thigh, repeating every 5 to 15 minutes. Antihistamines and steroids are adjuncts, not first-line.
- Traumatic lumbar puncture findings
- A traumatic tap shows red blood cell counts that decrease from tube to tube and a supernatant that clears after centrifugation, unlike subarachnoid hemorrhage with uniform blood and xanthochromia.
- Adult BLS compression parameters
- Deliver compressions at 100 to 120 per minute with a depth of 5 to 6 cm, using a 30:2 compression-to-ventilation ratio for a single rescuer, and keep interruptions under 10 seconds.
- DKA treatment sequence
- Begin isotonic fluids, start an insulin infusion once potassium is at least 3.3 mEq/L, and add dextrose when glucose falls below roughly 200 to 250 mg/dL while continuing insulin until the gap closes.
- Hyperkalemia with ECG changes
- Give intravenous calcium gluconate first for membrane stabilization, then shift potassium intracellularly with insulin plus glucose and albuterol, and arrange definitive removal by dialysis if refractory.
- CURB-65 components
- Confusion, urea greater than 7 mmol/L, respiratory rate at least 30, low blood pressure, and age 65 or older. Higher scores predict pneumonia mortality and guide inpatient versus outpatient care.
- Acute pancreatitis diagnosis
- Diagnosis requires two of three: characteristic epigastric pain radiating to the back, lipase greater than three times the upper limit of normal, or imaging findings consistent with pancreatitis.
- Thyroid storm treatment
- Use a beta-blocker for symptoms, a thionamide such as propylthiouracil, iodine given at least one hour after the thionamide, and glucocorticoid, with supportive care for fever and volume depletion.
- Stroke thrombolysis window
- Intravenous alteplase may be given within 4.5 hours of last known well after noncontrast CT excludes hemorrhage. Thrombectomy is an option up to 24 hours in selected large-vessel occlusion.
- Hardy-Weinberg carrier frequency
- For an autosomal recessive condition, p plus q equals 1 and p squared plus 2pq plus q squared equals 1; the heterozygous carrier frequency is 2pq, where q is the disease allele frequency.
- Renal clearance formula
- Clearance equals urine concentration times urine flow rate divided by plasma concentration. Inulin clearance equals glomerular filtration rate, while para-aminohippurate clearance approximates renal plasma flow.
- Oxygen content equation
- Arterial oxygen content equals 1.34 times hemoglobin times arterial saturation plus 0.003 times arterial oxygen tension, so hemoglobin and saturation dominate delivery far more than dissolved oxygen.
- Anion gap and delta-delta
- Anion gap equals sodium minus chloride plus bicarbonate, normal 8 to 12 mEq/L. Delta-delta compares the rise in anion gap to the fall in bicarbonate to detect mixed metabolic disorders.
- Virchow triad
- The three contributors to thrombosis are venous stasis, endothelial injury, and hypercoagulability. The triad frames risk assessment for deep vein thrombosis and pulmonary embolism.
- Antibiotic ribosomal targets
- Aminoglycosides and tetracyclines bind the 30S subunit; macrolides, chloramphenicol, and clindamycin bind the 50S subunit. Beta-lactams inhibit cell wall transpeptidase and fluoroquinolones inhibit DNA gyrase.
- Sensitivity and specificity use
- Sensitivity is true positives divided by all diseased; specificity is true negatives divided by all healthy. Highly sensitive tests rule out disease (SnNout); highly specific tests rule in disease (SpPin).
- Likelihood ratio calculation
- Positive likelihood ratio equals sensitivity divided by one minus specificity. Negative likelihood ratio equals one minus sensitivity divided by specificity. Values above 10 or below 0.1 substantially change probability.
- Number needed to treat
- Number needed to treat equals one divided by the absolute risk reduction; number needed to harm equals one divided by the absolute risk increase. Lower values indicate a larger clinical effect.
- SPIKES protocol
- A six-step framework for breaking bad news: Setting up the conversation, assessing Perception, obtaining Invitation, giving Knowledge, addressing Emotions with empathy, and summarizing Strategy.
- Teach-back method
- The clinician asks the patient to restate the plan or instructions in their own words, then clarifies misunderstandings. A correct restatement confirms comprehension better than asking whether they understand.
- Motivational interviewing OARS
- Core skills are open-ended questions, affirmations, reflections, and summaries. The clinician rolls with resistance rather than arguing, supporting the patient's own reasons for change.
- LEARN cross-cultural model
- Listen to the patient's perspective, Explain your view, Acknowledge differences and similarities, Recommend a plan, and Negotiate agreement that incorporates the patient's cultural context.
- HIPAA minimum necessary rule
- When using or disclosing protected health information, share only the minimum needed for the purpose. Disclosures for treatment, payment, and operations generally do not require patient authorization.
- Medicare Part A versus B
- Part A covers inpatient hospital, skilled nursing facility, hospice, and some home health care. Part B covers outpatient services, physician visits, durable medical equipment, and preventive services.