CRNI study materials
CRNI study resources

CRNI key terms

CRNI · Get comfortable with the vocabulary.

Teach-back method

A patient-education technique in which the learner explains or demonstrates information back in their own words, letting the nurse confirm understanding and correct misunderstandings before the patient self-manages therapy at home.

Related: Health literacy, Care coordination
Health literacy

The degree to which a person can obtain, process, and understand basic health information needed to make treatment decisions; limited health literacy calls for plain language, pictures, and repeated reinforcement.

Related: Teach-back method
Peripherally inserted central catheter (PICC)

A central venous catheter inserted through a peripheral arm vein and advanced until the tip rests in the lower superior vena cava, suitable for prolonged therapy, vesicant drugs, and hyperosmolar solutions.

Related: Tip location, Implanted port
Implanted port

A fully subcutaneous central venous access device with a self-sealing septum that is entered with a non-coring needle; it requires little care between uses and supports intermittent long-term therapy.

Related: Peripherally inserted central catheter (PICC), Hub disinfection
Tip location

The position of a central catheter's distal end, ideally at the cavoatrial junction, verified by radiograph or another approved method before the device is used for infusion.

Related: Peripherally inserted central catheter (PICC)
Dwell time

The planned or actual length of time a vascular access device remains in place; peripheral catheters are removed promptly once therapy ends or signs of complication appear.

Related: Phlebitis, Central line-associated bloodstream infection (CLABSI)
Positive-pressure flush

A flushing technique in which slight pressure is held on the syringe plunger while the catheter is clamped, preventing blood reflux into the tip and reducing occlusion risk in central devices.

Related: Occlusion, Hub disinfection
Smart pump

An electronic infusion device with dose-error-reduction software that alerts clinicians when programmed rates or doses fall outside configured limits, adding protection when high-alert drugs are infused.

Related: High-alert medication, Flow rate
Patient-controlled analgesia (PCA)

A programmable pump that lets a patient self-administer small preset bolus doses of an analgesic within lockout limits, providing rapid relief while limiting the risk of oversedation.

Related: High-alert medication, Smart pump
Backpriming

Filling secondary administration tubing with solution from the primary container by allowing backflow, establishing a secondary infusion without wasting drug or introducing air into the line.

Related: Flow rate, Y-site compatibility
Extravasation

Escape of a vesicant or irritant drug from the vein into surrounding tissue, causing pain, blistering, and possible necrosis; it requires stopping the infusion and following a drug-specific antidote protocol.

Related: Infiltration, Phlebitis
Infiltration

Leakage of non-vesicant fluid into surrounding tissue, producing swelling, coolness, and blanching at the site; the infusion is stopped, the catheter removed, and the limb elevated.

Related: Extravasation, Phlebitis
Phlebitis

Inflammation of a vein caused by mechanical, chemical, or bacterial irritation from a catheter or infusate, marked by redness, warmth, tenderness, or a palpable cord along the vessel.

Related: Infiltration, Dwell time
Occlusion

Partial or complete blockage of a catheter lumen by clot, precipitate, or mechanical pinch, preventing flush, blood return, or infusion and requiring cause-specific clearing rather than forceful flushing.

Related: Positive-pressure flush, Air embolism
Air embolism

Entry of air into the vascular system, often through an open or disconnected central catheter, causing sudden dyspnea, chest pain, and cardiovascular collapse; managed by clamping the line and positioning the patient.

Related: Occlusion
Fluid overload

Excess vascular volume from overly rapid or excessive infusion, producing dyspnea, edema, weight gain, and elevated filling pressures; managed by slowing the rate, elevating the head of bed, and giving prescribed diuretics.

Related: Transfusion-associated circulatory overload (TACO), Flow rate
Central line-associated bloodstream infection (CLABSI)

A laboratory-confirmed bloodstream infection in a patient whose central line was in place at least two calendar days before the event and with no other identified source; prevention relies on insertion and maintenance bundles.

Related: Aseptic non-touch technique (ANTT), Hub disinfection, Maximum sterile barrier precautions
Aseptic non-touch technique (ANTT)

A standardized approach to asepsis that protects key parts and key sites during a procedure through a defined sequence of hand hygiene, glove use, and clean or sterile technique.

Related: Central line-associated bloodstream infection (CLABSI), Hub disinfection
Maximum sterile barrier precautions

The full set of barriers - cap, mask, sterile gown, sterile gloves, and full-body drape - worn during central venous catheter insertion to reduce contamination and subsequent bloodstream infection.

Related: Central line-associated bloodstream infection (CLABSI), Aseptic non-touch technique (ANTT)
Hub disinfection

Cleaning the catheter hub or connector with an approved antiseptic using friction and the manufacturer's specified drying time before every access, which reduces organisms entering the lumen.

Related: Central line-associated bloodstream infection (CLABSI), Aseptic non-touch technique (ANTT)
High-alert medication

A drug that carries a heightened risk of significant harm when used in error, such as insulin, heparin, opioids, and concentrated electrolytes; these require standardized concentrations, labeling, and independent double checks.

Related: Smart pump, Patient-controlled analgesia (PCA)
Closed system transfer device

A device that mechanically prevents transfer of hazardous drug vapor or aerosol between vial, syringe, and catheter, protecting staff during preparation and administration of antineoplastic agents.

Related: High-alert medication
Type and screen

Pre-transfusion testing that determines ABO/Rh type and screens serum for unexpected antibodies; a negative screen permits rapid provision of compatible units when transfusion becomes urgent.

Related: Crossmatch
Crossmatch

The compatibility test that mixes donor red cells with the recipient's serum to detect clinically significant antigen-antibody reactions before the unit is transfused.

Related: Type and screen, Hemolytic transfusion reaction
Hemolytic transfusion reaction

Destruction of transfused red cells by recipient antibodies, producing fever, chills, flank pain, dark urine, and possible renal failure; the transfusion is stopped at once and the line kept open with saline.

Related: Type and screen, Crossmatch
Transfusion-related acute lung injury (TRALI)

Noncardiogenic pulmonary edema with hypoxemia developing within six hours of transfusion, often caused by donor antibodies; treatment is supportive, with oxygen and ventilatory assistance as needed.

Related: Transfusion-associated circulatory overload (TACO)
Transfusion-associated circulatory overload (TACO)

Hypervolemia with dyspnea, hypertension, and pulmonary edema caused by transfusion that is too rapid or too large, especially in cardiac or renal patients; managed with diuretics and slower rates.

Related: TRALI, Fluid overload
Total parenteral nutrition (TPN)

Intravenous nutrition containing carbohydrate, amino acids, lipid, electrolytes, vitamins, and trace elements, given through a central catheter because the final solution is highly concentrated.

Related: Osmolarity, Refeeding syndrome
Refeeding syndrome

A potentially fatal shift of electrolytes, most notably hypophosphatemia, that occurs when nutrition is reintroduced too rapidly to a malnourished patient; prevention requires gradual advancement and close electrolyte monitoring.

Related: Total parenteral nutrition (TPN)
Osmolarity

The concentration of dissolved particles in a solution; values above roughly 900 mOsm/L generally require central venous delivery to avoid vein irritation and phlebitis.

Related: Total parenteral nutrition (TPN), Phlebitis
Flow rate

The volume of fluid delivered per unit of time, usually expressed as milliliters per hour, calculated from the ordered volume and duration and set on a manual or electronic device.

Related: Smart pump, Dimensional analysis
Dimensional analysis

A calculation method that uses unit cancellation within a single equation to convert among doses, concentrations, and volumes, reducing setup errors in dosage and infusion rate problems.

Related: Flow rate
Y-site compatibility

The documented ability of two solutions or drugs to be infused simultaneously through the same connector without physical or chemical interaction such as precipitation, clouding, or inactivation.

Related: Occlusion, Flow rate
Care coordination

Deliberate organization of patient care activities and sharing of information among all participants to achieve safer, more effective, and more efficient care across settings and providers.

Related: SBAR handoff, Adherence
SBAR handoff

A structured communication format - Situation, Background, Assessment, Recommendation - used when transferring patient information between clinicians to reduce omissions and handoff errors.

Related: Care coordination
Adherence

The extent to which a person's behavior - taking medication, following a regimen, keeping appointments - matches agreed recommendations from the care team; supported by education and simplified regimens.

Related: Care coordination, Teach-back method
Infusion Therapy Standards of Practice

Consensus practice standards from the Infusion Nurses Society that define requirements for vascular access, administration, and related nursing care, and that underpin organizational policy and competency validation.

Related: Evidence-based practice
Evidence-based practice

Clinical decision-making that integrates the best available research, clinician expertise, and patient preferences; used to select and update infusion policies, products, and procedures.

Related: Infusion Therapy Standards of Practice, Root cause analysis
Root cause analysis

A structured team review of a serious event that traces causal and contributing factors in order to redesign systems and prevent recurrence rather than assign individual blame.

Related: Evidence-based practice