CRNI study materials
CRNI study resources

CRNI: Infection Prevention, Safety, and Risk Management

CRNI · Work through your exam, one topic at a time.

All guide sections

Infection Prevention, Safety, and Risk Management

The prevention bundle

Hand hygiene is the single most effective intervention. For central line insertion: chlorhexidine skin antisepsis, maximal sterile barrier precautions, optimal site selection, and daily review of line necessity. For maintenance: scrub the hub with an approved antiseptic for the required contact time (commonly 5–15 seconds) and allow it to dry; use aseptic non-touch technique for all access; change transparent semipermeable dressings every 5–7 days and gauze dressings every 48 hours, or sooner if soiled, damp, or loose; replace administration sets on the schedule defined by the type of therapy.

Safety and risk

Use standardized concentrations and independent double checks for high-alert drugs. Apply safe needle practices - do not recap, use needleless systems, and dispose of sharps immediately. Manage the environment: unclutter the work area, label lines and syringes, and trace every line from source to patient.

Risk management behaviors

Report incidents and near misses through the facility system; near misses are free lessons and should not be punished. Participate in root cause analysis for sentinel events. Speak up using structured communication (e.g., SBAR) and chain of command when a patient is at risk.

Trap: questions testing timing. Hub disinfection requires friction and drying time - the friction alone is not the standard. Similarly, dressing change frequency differs for gauze versus transparent film.

Worked example: A nurse swabs a needleless connector and immediately attaches the syringe. Correct critique: the antiseptic must be allowed to dry before access; skipping dry time undermines the aseptic technique.

Rule of thumb: if a line, syringe, or solution cannot be traced to its source, do not administer it.