Czech Gynaecology and Obstetrics Board Exam flashcards
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- Physiological anaemia of pregnancy
- Plasma volume increases about 40–50% while red cell mass rises only 20–25%, lowering haemoglobin by dilution. In the second and third trimester haemoglobin below 105 g/L is abnormal and warrants iron studies.
- Combined first-trimester screening
- Performed at 11+0 to 13+6 weeks using nuchal translucency, free beta-hCG, PAPP-A and maternal age. Detects roughly 85–90% of trisomy 21 cases at a 3–5% false-positive rate.
- Gestational diabetes diagnostic thresholds
- A 75 g oral glucose tolerance test at 24–28 weeks is diagnostic if fasting glucose is at least 5.1 mmol/L, one-hour glucose at least 10.0 mmol/L, or two-hour glucose at least 8.5 mmol/L.
- Anti-D prophylaxis schedule
- RhD-negative non-sensitised women receive anti-D immunoglobulin around 28 weeks, within 72 hours of delivery, and after abortion, amniocentesis or antepartum bleeding to prevent alloimmunisation.
- Preeclampsia diagnostic criteria
- Hypertension at least 140/90 mmHg after 20 weeks plus proteinuria at least 300 mg per 24 hours, or hypertension with maternal organ dysfunction such as thrombocytopenia, renal, hepatic or neurological involvement.
- Magnesium sulphate in eclampsia
- Loading dose 4 g intravenously over 20 minutes, then 1 g per hour infusion. Monitor respiratory rate, reflexes and urine output; calcium gluconate is the antidote for toxicity.
- Antenatal corticosteroids
- Betamethasone 12 mg intramuscularly twice, 24 hours apart, given between 24+0 and 34+0 weeks to accelerate fetal lung maturity and reduce respiratory distress syndrome, intraventricular haemorrhage and neonatal death.
- Late decelerations on CTG
- Decelerations that begin after the contraction peak and recover after it ends, reflecting uteroplacental insufficiency. With reduced variability they require immediate intrauterine resuscitation and expedited delivery.
- Shoulder dystocia manoeuvres
- Start with McRoberts manoeuvre and suprapubic pressure, then attempt internal rotation, posterior arm delivery or all-fours position. Fundal pressure and excessive traction are contraindicated because they worsen impaction.
- Postpartum haemorrhage first-line treatment
- Uterine massage, oxytocin 5 IU slow intravenous or 10 IU intramuscular, tranexamic acid 1 g intravenously within 3 hours, then ergometrine, carboprost or misoprostol if bleeding continues.
- Operative vaginal delivery prerequisites
- Full cervical dilatation, engaged head at or below station zero, known fetal position, empty bladder, adequate analgesia, no cephalopelvic disproportion, and an experienced operator prepared to abandon the attempt.
- Risk of malignancy index
- RMI equals CA-125 multiplied by menopausal status score and ultrasound score. Values above 200–250 indicate high risk of ovarian malignancy and prompt referral to a gynaecological oncology centre.
- FIGO staging of cervical cancer
- Staging is clinical but imaging and pathology may be incorporated. Stage IB1 tumours are 2 cm or less, IB2 are over 2 cm to 4 cm, and IB3 are over 4 cm in greatest dimension.
- Endometrial cancer risk factors
- Obesity, unopposed oestrogen exposure, diabetes, nulliparity, tamoxifen use and Lynch syndrome increase risk. Postmenopausal bleeding requires endometrial biopsy and transvaginal ultrasound.
- Complete hydatidiform mole
- Usually 46,XX with entirely paternal chromosomes, absent fetal tissue, markedly elevated beta-hCG and a snowstorm ultrasound appearance. Follow beta-hCG to zero and treat plateau or rise with chemotherapy.
- PALM-COEIN classification
- Classifies abnormal uterine bleeding into structural causes (polyp, adenomyosis, leiomyoma, malignancy) and non-structural causes (coagulopathy, ovulatory dysfunction, endometrial, iatrogenic, not otherwise classified).
- Endometriosis diagnosis and treatment
- Ectopic endometrial tissue causing dysmenorrhoea, deep dyspareunia and infertility. Laparoscopy with histology confirms diagnosis; treatment includes NSAIDs, hormonal suppression, GnRH agonists and surgical excision.
- POP-Q staging
- Pelvic organ prolapse quantification uses six defined points and three measurements. Stage I is more than 1 cm above the hymen, stage II is within 1 cm, stage III beyond 1 cm, stage IV complete eversion.
- Polycystic ovary syndrome criteria
- Rotterdam criteria require two of three: oligo-ovulation or anovulation, clinical or biochemical hyperandrogenism, and polycystic ovaries on ultrasound. Treatment includes lifestyle change, metformin, letrozole or clomiphene.
- Ovarian hyperstimulation syndrome prevention
- Use a GnRH antagonist protocol with agonist trigger, freeze all embryos, give cabergoline, and avoid hCG luteal support in high-risk women with many follicles or high oestradiol.
- WHO anovulation groups
- Group I is hypogonadotropic with low FSH, group II is normogonadotropic typically due to PCOS, and group III is hypergonadotropic ovarian failure requiring donor oocytes.
- Urodynamic stress incontinence
- Involuntary urine leakage during filling cystometry when abdominal pressure rises, without a detrusor contraction. It confirms the diagnosis before continence surgery such as a tension-free vaginal tape.
- Apical prolapse repair
- Sacrospinous fixation or sacrocolpopexy corrects uterine or vault prolapse. Vaginal hysterectomy with McCall culdoplasty is an alternative when the uterus is removed.
- TURP syndrome in hysteroscopy
- Absorption of hypotonic distension fluid during monopolar hysteroscopic resection causes dilutional hyponatraemia, hypervolaemia, confusion and seizures. Fluid deficit limits are 750 mL for hypotonic and 1000 mL for saline media.
- Laparoscopic entry techniques
- Closed Veress needle entry is common, but open Hasson entry is preferred after previous abdominal surgery, in obesity or suspected adhesions. Palmer's point is used when the umbilicus is unsuitable.
- Bacterial vaginosis diagnosis
- Amsel criteria require three of four: thin grey discharge, vaginal pH above 4.5, positive whiff test, and clue cells on microscopy. Treatment is metronidazole or vaginal clindamycin; partners are not treated.
- Chlamydia trachomatis treatment
- Doxycycline 100 mg twice daily for seven days or azithromycin 1 g single dose, with partner notification and testing. Untreated infection causes pelvic inflammatory disease, ectopic pregnancy and tubal infertility.
- Syphilis in pregnancy
- Screen with VDRL or RPR and confirm with treponemal tests. Treat with benzathine penicillin G 2.4 million IU intramuscularly to prevent congenital syphilis; penicillin allergy requires desensitisation.
- Second-trimester anomaly scan
- Performed at 18–22 weeks to assess fetal anatomy, placental localisation, amniotic fluid volume and cervical length. It detects major structural anomalies and informs further prenatal diagnosis.
- Umbilical artery Doppler
- Absent or reversed end-diastolic flow indicates severe placental insufficiency and fetal hypoxia. Management depends on gestational age and may require delivery after corticosteroids.
- Abortion legislation in Czech Republic
- Termination on request is legal up to 12 weeks of gestation after counselling and a waiting period. Later termination is permitted only for genetic or serious maternal indications under statutory conditions.
- Perimortem caesarean section
- In maternal cardiac arrest beyond 20 weeks, perform manual left uterine displacement and start perimortem caesarean within 4–5 minutes if resuscitation fails, to improve maternal and fetal survival.