GTLE Biology key terms
GTLE Biology · Get comfortable with the vocabulary.
- Homeostasis
- Related: Negative feedback, Osmosis
The maintenance of a stable internal environment within an organism, such as constant body temperature or blood glucose, despite changes in external conditions. It relies on negative feedback loops detecting and correcting deviations.
- Negative feedback
- Related: Homeostasis, Hormone
A control mechanism where a change from a set point triggers a response that counteracts that change, restoring the original value. Common in temperature regulation, hormone control, and blood sugar management.
- Osmosis
- Related: Diffusion, Homeostasis
The net movement of water molecules across a partially permeable membrane from a region of higher water potential to one of lower water potential. It is passive and requires no energy input.
- Diffusion
- Related: Osmosis, Active transport
The passive spreading of particles from a region of higher concentration to a region of lower concentration, driven by random molecular motion. Rate depends on concentration gradient, temperature, surface area, and distance.
- Active transport
- Related: Diffusion, Enzyme
Movement of ions or molecules across a membrane against their concentration gradient using carrier proteins and energy from ATP hydrolysis. It allows cells to accumulate substances they need at higher internal concentrations.
- Enzyme
- Related: Active site, Denaturation
A biological catalyst, usually a globular protein, that speeds up reactions by lowering activation energy. Its activity depends on shape, temperature, pH, and substrate concentration, and it is not consumed.
- Active site
- Related: Enzyme, Denaturation
The specific region of an enzyme where the substrate binds and the reaction occurs. Its shape is complementary to the substrate, and alteration of this shape reduces or destroys catalytic activity.
- Denaturation
- Related: Enzyme, Active site
Loss of a protein's three-dimensional structure caused by heat, extreme pH, or chemicals, breaking bonds that maintain shape. For enzymes this destroys the active site and abolishes catalytic function irreversibly in most cases.
- Mitosis
- Related: Meiosis, Cell cycle
Nuclear division producing two genetically identical daughter cells with the same chromosome number as the parent. It underpins growth, repair, and asexual reproduction in eukaryotes.
- Meiosis
- Related: Mitosis, Allele
Reduction division producing four haploid gametes from one diploid cell, involving two divisions and crossing over. It generates genetic variation through independent assortment and recombination.
- Allele
- Related: Genotype, Meiosis
One of two or more alternative versions of a gene occupying the same locus on homologous chromosomes. Combinations of alleles determine genotype and contribute to phenotype variation.
- Genotype
- Related: Allele, Phenotype
The genetic makeup of an organism at one or more loci, described by the alleles present, such as homozygous dominant or heterozygous. It interacts with environment to produce the observable phenotype.
- Phenotype
- Related: Genotype, Natural selection
The observable characteristics of an organism resulting from the interaction between its genotype and environmental factors. Examples include eye colour, blood group, and enzyme activity levels.
- Natural selection
- Related: Phenotype, Adaptation
The process whereby individuals with inherited traits better suited to their environment survive and reproduce more successfully, increasing the frequency of those alleles in later generations.
- Adaptation
- Related: Natural selection
An inherited feature or behaviour that increases an organism's chance of survival and reproduction in its habitat. Adaptations arise through natural selection over many generations.
- Photosynthesis
- Related: Respiration, Chlorophyll
The light-dependent synthesis of glucose from carbon dioxide and water in chloroplasts, releasing oxygen. Light energy is captured by chlorophyll and converted into chemical energy in organic molecules.
- Respiration
- Related: Photosynthesis, ATP
The controlled release of energy from organic molecules such as glucose, producing ATP. Aerobic respiration uses oxygen and yields carbon dioxide and water; anaerobic respiration occurs without oxygen.
- ATP
- Related: Respiration, Active transport
Adenosine triphosphate, the universal energy currency of cells. Hydrolysis of its terminal phosphate bond releases energy that drives endergonic processes including active transport and synthesis reactions.
- Chlorophyll
- Related: Photosynthesis
The green pigment in chloroplasts that absorbs mainly red and blue light for photosynthesis while reflecting green wavelengths. Different chlorophyll types absorb slightly different wavelengths.
- Ecosystem
- Related: Food chain, Biodiversity
A community of interacting organisms together with the non-living components of their environment, such as soil, water, and climate. Energy flows through it while nutrients are recycled.
- Food chain
- Related: Ecosystem, Trophic level
A sequence showing the transfer of energy from producers through primary and secondary consumers to decomposers. Arrows indicate direction of energy flow, and energy is lost at each trophic level.
- Trophic level
- Related: Food chain, Ecosystem
The position an organism occupies in a food chain, such as producer, primary consumer, or secondary consumer. Biomass and energy generally decrease at higher trophic levels.
- Biodiversity
- Related: Ecosystem, Conservation
The variety of living organisms in an area, encompassing species richness, genetic diversity within species, and ecosystem diversity. It supports ecosystem stability and resilience to change.
- Conservation
- Related: Biodiversity
The protection and management of species, habitats, and genetic resources to maintain biodiversity and prevent extinction. Strategies include protected areas, captive breeding, and seed banks.
- Constructivism
- Related: Misconception, Formative assessment
A learning theory holding that learners build new understanding by connecting new information to existing knowledge and experience. Teaching therefore starts from prior conceptions and uses active, hands-on tasks.
- Misconception
- Related: Constructivism, Formative assessment
A persistent, scientifically incorrect idea a learner already holds, such as believing plants get food from soil. Effective teaching elicits and directly challenges such ideas rather than ignoring them.
- Formative assessment
- Related: Summative assessment, Constructivism
Ongoing assessment used during teaching to identify what learners understand and to adjust instruction accordingly. It is low-stakes and feedback-focused, contrasting with summative assessment of final achievement.
- Summative assessment
- Related: Formative assessment, Validity
Assessment carried out at the end of a unit or course to judge overall achievement against standards. Results are typically graded and reported, and may inform progression or certification decisions.
- Practical work
- Related: Scientific inquiry, Formative assessment
Learning activities in which students handle equipment and materials to investigate biological questions. Well-designed practicals develop investigative skills and support understanding of concepts and the nature of evidence.
- Scientific inquiry
- Related: Practical work, Validity
The process of asking questions, formulating testable hypotheses, planning fair investigations, collecting and analysing data, and drawing evidence-based conclusions. It reflects how scientific knowledge is generated.
- Differentiation
- Related: Scaffolding, Formative assessment
Adapting content, tasks, support, or outcomes to meet the varied readiness and needs of learners in the same class. It aims to give all students appropriate challenge and access to the curriculum.
- Scaffolding
- Related: Differentiation, Zone of proximal development
Temporary structured support, such as models, prompts, or partially completed tasks, that enables learners to accomplish a task they could not yet do independently. Support is gradually withdrawn as competence grows.
- Zone of proximal development
- Related: Scaffolding
The gap between what a learner can do unaided and what they can achieve with guidance from a more capable person. Instruction is most effective when targeted within this range.
- Validity
- Related: Reliability, Summative assessment
The extent to which an assessment or investigation measures what it claims to measure. In experiments, validity requires controlling confounding variables so results can be attributed to the independent variable.
- Reliability
- Related: Validity, Precision
The consistency of a measurement or assessment when repeated under the same conditions. Reliable methods give similar results on repeat trials, though a reliable measure may still be invalid.
- Accuracy
- Related: Precision, Reliability
How close a measured value is to the true or accepted value. Accuracy differs from precision, which concerns the closeness of repeated measurements to each other.
- Precision
- Related: Accuracy, Reliability
How close repeated measurements are to one another, reflecting the spread of results. Precise measurements may still be inaccurate if there is a systematic error.
- Control variable
- Related: Validity, Scientific inquiry
A factor kept constant across experimental groups so that it cannot influence the outcome. Controlling relevant variables strengthens the validity of conclusions about the independent variable.
- Ethics in biology
- Related: Practical work, Risk assessment
Principles governing responsible research and teaching involving living organisms, including informed consent, animal welfare, and safe handling of microorganisms. Ethical approval and risk assessment are usually required before practical work.
- Risk assessment
- Related: Ethics in biology, Practical work
A systematic identification of hazards in an activity and evaluation of the likelihood and severity of harm, followed by measures to reduce risk. It underpins safe laboratory and fieldwork practice.
- Standard deviation
- Related: Mean, Precision
A measure of the spread of data around the mean, calculated from the square root of the variance. A large value indicates widely dispersed results and greater uncertainty in the mean.
- Mean
- Related: Standard deviation
The arithmetic average of a set of values, found by summing them and dividing by the number of values. It summarises central tendency but is sensitive to extreme values.
- Magnification
- Related: Resolution
The number of times an image is larger than the actual object, calculated as image size divided by actual size. Units must be converted consistently, usually to millimetres or micrometres.
- Resolution
- Related: Magnification
The smallest distance at which two points can be distinguished as separate. It is limited by the wavelength of radiation used and is distinct from magnification.
- Rate of reaction
- Related: Enzyme
The change in amount of reactant or product per unit time, often expressed per second or per minute. Graphs of product against time allow comparison of initial rates between conditions.