MLT Registration study plan
MLT Registration · Give each week a clear focus.
8 weeks · About 6 hours per week
Blood Banking & Coagulation
Map the ABO/Rh antigen-antibody system from memory, then label every discrepancy scenario (weak subgroups, missing reverse type, mixed field) with the resolution step you would take
Differentiate the major crossmatch, type and screen, and electronic crossmatch by listing the patient history and specimen requirements that qualify each one
Build a one-page table of transfusion reactions (hemolytic, febrile non-hemolytic, allergic, TRALI, TACO, septic, delayed) with timing, hallmark findings, and first action for each
Trace the coagulation cascade by factor number and state which screening test (PT, aPTT, thrombin time, fibrinogen, mixing study) is prolonged when each factor is deficient
Solve five mixing-study patterns and decide whether the result points to a factor deficiency or an inhibitor
Your checkpoint
A two-page reference sheet covering ABO/Rh discrepancies, crossmatch selection, transfusion reaction triage, and mixing-study interpretation, scored against a 20-item self-quiz at 80% or better
Blood Banking & Coagulation
Classify the blood products (packed red cells, platelets, FFP, cryoprecipitate) by storage temperature, shelf life, and the indication that justifies each transfusion
Apply pretransfusion specimen labeling and identification rules to three written error scenarios and state the corrective action for each
Interpret a full coagulation panel for disseminated intravascular coagulation, heparin therapy, and liver disease, and justify each interpretation in two sentences
Explain how heparin, direct oral anticoagulants, and warfarin each distort PT and aPTT results and name the appropriate monitoring test for each
Perform the antibody screen workflow in writing for a patient with a positive screen, including panel interpretation and selection of antigen-negative units
Your checkpoint
A completed case workbook of eight written transfusion and coagulation cases, each with interpretation, next test, and action, reviewed for accuracy against reference texts
Hematology & Clinical Chemistry
Interpret a complete blood count with differential and flag the three findings that demand a manual smear review
Describe red cell morphology terms (target cells, schistocytes, spherocytes, basophilic stippling) and match each to one condition that produces it
Compare the anemias by MCV, reticulocyte count, and iron studies, and state the discriminating laboratory result for each
Explain the principle, interference, and clinical use of the basic metabolic panel, hepatic panel, and cardiac troponin assays
Distinguish hemolysis from in vivo and in vitro causes using haptoglobin, LDH, bilirubin, and specimen inspection
Your checkpoint
A graded 30-question self-test on hematology and chemistry interpretation with every missed item rewritten as a corrected flashcard
Hematology & Clinical Chemistry
Work through leukemia and lymphoma diagnosis by naming the peripheral smear, flow cytometry, and cytochemical findings that separate acute from chronic and myeloid from lymphoid
Interpret hemoglobin electrophoresis patterns for sickle cell trait, sickle cell disease, and beta-thalassemia minor
Calculate and correct laboratory values (anion gap, corrected calcium, osmolality, creatinine clearance) and state when each correction is clinically necessary
Explain quality control rules for chemistry and hematology analyzers and decide whether to report, repeat, or reject a run that fails a rule
Describe body fluid analysis criteria for classifying a pleural or ascitic fluid as exudate or transudate
Your checkpoint
A written mid-plan exam of 40 mixed items across domains 1 through 4 completed under timed conditions with a recorded score and error log
Immunology & Microbiology
Map innate and adaptive immunity and place each laboratory test (ELISA, agglutination, immunofluorescence, flow cytometry, molecular amplification) at the step it measures
Interpret hepatitis and HIV serology patterns including window periods, and state the confirmatory or supplemental test for each reactive screen
Explain sensitivity, specificity, and predictive value and calculate each from a supplied two-by-two table
Classify the major bacterial pathogens by Gram stain, colony morphology, and key biochemical reactions used for identification
Describe antimicrobial susceptibility testing methods and interpret a minimum inhibitory concentration against a breakpoint category
Your checkpoint
A completed serology and microbiology problem set of 25 items, including three two-by-two calculations and five organism identification pathways, with all answers justified in writing
Microbiology & Phlebotomy
Outline the specimen collection and processing requirements that differ among blood culture, anaerobic culture, viral transport, and stool culture, and state the error each requirement prevents
Explain the order of draw, tube additive and color, and the tests affected when the order is reversed
Apply the CLSI skin antisepsis and venipuncture sequence to written scenarios involving difficult draws, hemolysis, and short draws, and state the corrective step
Describe the safe handling and rejection criteria for specimens that pose a biohazard or are compromised by labeling or volume errors
Identify the preanalytical errors most likely to cause falsely elevated potassium, falsely low glucose, and spurious coagulation results
Your checkpoint
A one-page phlebotomy quick-reference card plus a 15-item preanalytical error quiz scored at 90% or better
Laboratory Administration & Blood Banking
Explain the regulatory framework that governs the clinical laboratory, including accreditation, proficiency testing, and the requirement to document corrective action for failed challenges
Describe quality management elements covering document control, competency assessment, and instrument validation, and state the record each one requires
Apply root cause analysis to a written specimen misidentification event and produce a corrective and preventive action plan
Review blood bank quality requirements for reagent and unit storage, record retention, and look-back procedures
Interpret a laboratory budget variance and staffing scenario and justify a recommendation in writing
Your checkpoint
A written corrective and preventive action report for one simulated laboratory error, including root cause, corrective action, preventive action, and follow-up metric
Blood Banking & Clinical Chemistry & Coagulation & Hematology & Immunology & Microbiology & Phlebotomy & Laboratory Administration
Complete two full-length timed practice exams and record the score by domain to expose remaining weak areas
Re-drill every missed item from weeks 1 through 7 and rewrite each as a one-line rule you can recall without prompting
Recite the critical values and safety actions for transfusion, chemistry, and coagulation results that require immediate notification
Simulate a high-stress case set combining a transfusion reaction, an abnormal coagulation panel, and a positive culture, and defend each decision in writing
Your checkpoint
A final readiness report showing practice exam scores, a domain-by-domain trend, and a prioritized list of no more than ten items for last-week review
Milestones
Week 2: Score 80% or better on the transfusion and coagulation case workbook and explain every mixing-study interpretation without notes
Week 4: Score 75% or better on the timed 40-item mid-plan exam, with no single domain below 60%
Week 6: Score 90% or better on the preanalytical error quiz and correctly state the order of draw and rejection criteria from memory
Week 8: Score 80% or better on both full-length practice exams with every domain at or above 70% and fewer than ten open review items