IB Biology HL study materials
IB Biology HL study resources

IB Biology HL study plan

IB Biology HL · Give each week a clear focus.

8 weeks · About 7 hours per week

Week 1

Unity and Diversity

  • Build a comparison table of the three domains of life and of the major eukaryotic kingdoms, listing cell type, cell wall composition, nutrition mode, and one distinguishing organelle for each group.

  • Construct a dichotomous key that separates at least eight named organisms using observable features only, then test the key on three unfamiliar organisms and revise any ambiguous couplet.

  • Explain how cladistics differs from Linnaean classification, using one example where a traditional grouping conflicts with a clade, and state which evidence (molecular or morphological) supports each.

  • Describe the evidence for the endosymbiotic theory of mitochondria and chloroplasts, naming at least four independent lines of evidence and one counter-argument with its rebuttal.

  • Sketch and label the structure of a bacterial cell, a plant cell, and an animal cell side by side, annotating three structures that are present in only one of the three.

Your checkpoint

A one-page annotated classification and cell-structure summary sheet, containing the comparison table, the tested dichotomous key, and the three labelled cell sketches, that you can redraw from memory in under 10 minutes.

Week 2

Unity and Diversity & Continuity and Change

  • Explain the mechanism of natural selection as a five-step chain (variation, heritability, differential survival, change in allele frequency, reproductive isolation) and apply it to one named example of directional selection.

  • Distinguish between analogous and homologous structures and use each concept to evaluate a claim about convergent evolution in two named species.

  • Describe the processes of speciation (allopatric and sympatric) and identify the specific barrier operating in two named case studies.

  • Outline the evidence for evolution from molecular data, including the use of cytochrome c or ribosomal RNA sequence comparisons, and explain why molecular clocks are only approximate.

  • Compare the rates and patterns of evolution proposed by gradualism and punctuated equilibrium, and state which fossil evidence supports each.

Your checkpoint

A written answer of 250-350 words to a past-paper-style question on speciation and evidence for evolution, self-marked against the mark scheme with missing points highlighted in a different colour.

Week 3

Form and Function

  • Draw and label the fluid mosaic model of the membrane, and explain the function of phospholipids, cholesterol, glycoproteins, and integral and peripheral proteins in transport and recognition.

  • Compare simple diffusion, facilitated diffusion, osmosis, and active transport in a table covering concentration gradient direction, energy requirement, membrane protein involvement, and one biological example of each.

  • Explain how surface area to volume ratio constrains cell size and shape, and calculate the ratio for three cells of different dimensions to show the trend.

  • Describe the structure and function of the villus, the alveolus, and the nephron, identifying the specific structural adaptation that maximises exchange in each.

  • Explain the role of the heart in double circulation, tracing the pathway of blood through the chambers, valves, and major vessels, and relating the thickness of each chamber wall to its function.

Your checkpoint

A labelled diagram portfolio of five exchange surfaces (membrane, villus, alveolus, nephron, root hair), each with a caption of two to three sentences linking structure to function, checked against a syllabus checklist for missing labels.

Week 4

Form and Function & Experimental Skills and Internal Assessment

  • Interpret a set of transport data (for example, water potential measurements or rates of diffusion at different concentrations) by calculating means, identifying the trend, and stating one limitation of the method used.

  • Design a controlled experiment to investigate the effect of one named variable on osmosis in plant tissue, specifying the independent, dependent, and at least three controlled variables, plus how each is measured or monitored.

  • Explain how to reduce error and uncertainty in a practical, distinguishing between random and systematic error and between precision and accuracy, with one concrete example of each.

  • Describe how to construct and use a calibration curve, and state the assumptions required when interpolating a value from it.

  • Evaluate the strengths and weaknesses of a described experimental method and propose two specific improvements with justification.

Your checkpoint

A full internal-assessment-style practical report (research question, variables table, method, raw data table with units and uncertainties, processed data, and evaluation) of 600-900 words on an osmosis or enzyme-rate investigation.

Week 5

Interaction and Interdependence

  • Construct food chains and webs from a described community and identify producers, consumers, decomposers, and trophic levels, then calculate the energy transfer efficiency between two consecutive levels.

  • Explain why energy is lost at each trophic level and use this to justify the typical limit on the number of trophic levels in a food chain.

  • Describe the carbon cycle and the nitrogen cycle, naming the specific organisms and processes at each step, and explain how one human activity disrupts each cycle.

  • Explain the greenhouse effect, distinguishing natural from enhanced, and evaluate two named mitigation strategies by their mechanism and their limitation.

  • Describe the process of eutrophication and the mechanism by which it reduces dissolved oxygen, and propose two management interventions with justification.

Your checkpoint

A hand-drawn carbon and nitrogen cycle diagram with every arrow labelled by process and organism type, plus a 200-word explanation of one human disruption to each cycle, marked against a syllabus checklist.

Week 6

Interaction and Interdependence & Continuity and Change

  • Explain the principles of Hardy-Weinberg equilibrium, state its five conditions, and calculate allele and genotype frequencies from given data, including one case where the observed frequencies deviate and one reason why.

  • Describe the causes of variation (mutation, meiosis, random fertilisation, sexual reproduction) and explain how each contributes to genetic diversity in a population.

  • Explain the structure and behaviour of chromosomes in meiosis, including crossing over and independent assortment, and relate each to genetic variation.

  • Outline the inheritance of a named genetic disorder, using a pedigree or test-cross to predict the probability of an affected offspring.

  • Explain how antibiotic resistance in bacteria demonstrates natural selection in real time, and describe one mechanism of horizontal gene transfer that accelerates it.

Your checkpoint

A worked problem set of six genetics calculations (three Hardy-Weinberg, three monohybrid or test-cross) with full working shown and each final answer checked against an independently derived estimate.

Week 7

Continuity and Change

  • Describe the structure of DNA and RNA and explain how the structure of DNA enables semi-conservative replication, naming the enzymes involved at each step.

  • Explain the processes of transcription and translation, and describe one named mutation and its effect on the polypeptide produced.

  • Describe the polymerase chain reaction and gel electrophoresis, and explain how each is used in a named application such as DNA profiling or gene testing.

  • Explain the principles of genetic modification and evaluate one named example (for example, Golden Rice or Bt maize) by benefit, risk, and ethical consideration.

  • Compare mitosis and meiosis in a table covering number of divisions, crossing over, chromosome number in daughter cells, and biological purpose.

Your checkpoint

A single A3-style summary map linking DNA structure, replication, transcription, translation, mutation, PCR, and one application, with every arrow labelled by the process or enzyme involved.

Week 8

Unity and Diversity & Form and Function & Interaction and Interdependence & Continuity and Change & Experimental Skills and Internal Assessment

  • Complete two full timed practice papers under exam conditions and self-mark against the mark scheme, recording every lost mark by domain.

  • Identify the three weakest sub-topics from the marked papers and write a one-page correction sheet for each, stating the misconception and the correct statement.

  • Rehearse data-analysis and extended-response technique: practise interpreting a graph with error bars and structuring a six-mark evaluation answer with a clear judgement.

  • Recite from memory the core definitions and units for the five domains, checking each against the syllabus glossary and correcting any drift.

  • Review the internal-assessment criteria and annotate your week-4 report to show where each criterion is evidenced, then revise one section to strengthen the weakest criterion.

Your checkpoint

A marked-paper error log listing every lost mark with its domain, sub-topic, cause (knowledge, application, or careless), and the corrected answer, plus three completed correction sheets.

Milestones

Week 2: You can reproduce the three-domain comparison table and the five-step natural selection chain from memory in under 15 minutes, and your week-2 written answer scores at least 70% of the available marks against the mark scheme.

Week 4: Your practical report contains all internal-assessment sections, includes a raw data table with units and uncertainties, and shows at least one processed calculation with a stated uncertainty, and you can name the controlled variables without notes.

Week 6: All six genetics calculations are correct on independent re-derivation, and you can state the five Hardy-Weinberg conditions and apply them to a new data set without consulting notes.

Week 8: Both timed practice papers are completed within the allotted time, your error log shows fewer repeated causes than in week 1, and every domain has at least one correction sheet or a stated reason none was needed.