Israel Pharmacist Licensing Exam study plan
Israel Pharmacist Licensing Exam · Give each week a clear focus.
8 weeks · About 6 hours per week
Pharmacology and Pharmacotherapeutics
Map Domain 1 into a one-page drug-class grid covering cardiovascular, antidiabetic, anticoagulant, and psychotropic agents, with mechanism, key adverse effects, and monitoring parameter for each class
Explain the mechanism of action and clinically relevant adverse effects for the 40 highest-yield drug classes without consulting notes
Distinguish first-line from add-on therapy for hypertension, type 2 diabetes, heart failure, and major depression, citing the reasoning behind each step
Solve 30 applied pharmacology vignettes and log every wrong answer with the underlying mechanism gap
Your checkpoint
A 40-class drug grid plus a written error log of at least 30 vignettes with corrected mechanisms
Pharmacology and Pharmacotherapeutics & Pharmacokinetics, Biopharmaceutics, and Therapeutic Drug Monitoring
Apply pharmacokinetic equations (clearance, volume of distribution, half-life, loading and maintenance dose) to calculate doses in worked scenarios
Interpret therapeutic drug monitoring results for digoxin, lithium, vancomycin, phenytoin, and tacrolimus, and adjust dosing accordingly
Explain how hepatic impairment, renal impairment, and enzyme induction or inhibition change drug selection and dose
Predict bioavailability and bioequivalence implications of formulation and food effects on absorption
Your checkpoint
A 20-item calculation and TDM interpretation worksheet with full worked solutions and at least 85% self-scored accuracy
Pharmacy Law, Regulation, and Ethics in Israel & Dispensing, Prescription Handling, and Pharmaceutical Care
Outline the Israeli regulatory framework: Ministry of Health authorization of medicines, pharmacist licensure, prescription-only versus over-the-counter classification, and controlled-substance handling requirements
Describe pharmacist legal duties in dispensing, generic substitution, record retention, and reporting of adverse drug reactions
Apply an ethical decision framework to dispensing dilemmas such as suspected forged prescriptions, patient confidentiality, and refusal to dispense
Process 15 mock prescriptions end to end, detecting dosing errors, interactions, and legal defects
Your checkpoint
A dispensing checklist and a written log of 15 resolved mock prescriptions, each with the legal and ethical reasoning documented
Pharmaceutical Chemistry and Drug Structure–Activity Relationships & Pharmaceutics, Dosage Forms, and Pharmaceutical Technology
Relate functional groups and stereochemistry to solubility, ionization, receptor binding, and metabolic stability for major drug families
Explain prodrug design rationale using at least three concrete examples
Match dosage form selection to patient and drug factors, including pediatric, geriatric, and dysphagia cases
Compare modified-release technologies and describe the clinical risks of crushing or splitting each type
Your checkpoint
A structure–activity and formulation reference sheet covering 25 drugs, cross-checked against a self-made 25-question quiz scoring at least 80%
Clinical Pharmacy and Patient Safety & Dispensing, Prescription Handling, and Pharmaceutical Care
Analyze medication error case scenarios using root-cause reasoning and propose system-level preventive controls
Construct a pharmaceutical care plan for a polymorbid patient, covering problem list, goals, intervention, and follow-up monitoring
Identify high-alert medications and the double-check and look-alike/sound-alike safeguards that apply to each
Explain pharmacovigilance workflow from suspected reaction to report submission and follow-up
Your checkpoint
One complete written pharmaceutical care plan for a polymorbid case plus a medication error analysis with three system-level recommendations
Pharmacognosy, Biotechnology, and Biologic Medicines & Sterile Compounding, Aseptic Technique, and Hospital Pharmacy Practice
Differentiate origin, structure, immunogenicity risk, and regulatory pathway for small-molecule drugs, biosimilars, and advanced therapies
Explain the pharmacology and handling requirements of major biologics, including cold-chain and stability considerations
Sequence the steps of aseptic technique, including hand hygiene, garbing, disinfection, and first-air considerations for a laminar airflow hood
Calculate sterile compounding quantities and dilutions, and identify incompatibilities for common intravenous admixtures
Your checkpoint
A written aseptic technique procedure with a companion 10-item IV compatibility and dilution calculation set, all answers justified
Public Health, Vaccines, and Health-System Literacy & Pharmacology and Pharmacotherapeutics
Describe the Israeli national immunization schedule, vaccine storage requirements, and cold-chain breach management
Explain the pharmacist's role in vaccine counseling, screening for contraindications, and reporting adverse events following immunization
Outline health-system structures relevant to pharmacy practice, including health funds, hospital pharmacy, and community pharmacy interfaces
Rehearse counseling scripts for vaccination hesitancy and for two chronic-disease adherence scenarios
Your checkpoint
A one-page vaccine counseling and cold-chain quick reference plus two recorded or written counseling scripts reviewed against a self-built checklist
Pharmacology and Pharmacotherapeutics & Pharmacokinetics, Biopharmaceutics, and Therapeutic Drug Monitoring & Pharmacy Law, Regulation, and Ethics in Israel & Clinical Pharmacy and Patient Safety
Complete two full-length timed mock exams under exam conditions and score each by domain
Re-drill every missed item from weeks 1 through 7 until each is answered correctly twice in a row
Consolidate the highest-yield facts for each domain into a single condensed review sheet
Rehearse the calculation and TDM question types until completion is accurate and time-efficient
Your checkpoint
Two completed timed mock exams with domain score breakdown and a final condensed review sheet covering all ten domains
Milestones
Week 2: Score at least 80% on the self-made 40-class pharmacology and 20-item calculation set combined; if below, repeat week 1 error log before advancing
Week 4: Complete the 15 mock prescriptions with zero undetected legal or dosing defects and score at least 80% on the structure–activity and formulation quiz
Week 6: Produce the aseptic technique procedure and score 100% on the IV dilution set, since sterile compounding errors are not tolerable at partial accuracy
Week 8: Achieve at least 70% overall on both timed mock exams with no domain below 60%; any domain below 60% triggers a targeted one-day re-drill before the exam