IIT JAM MA flashcards
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32 cards. Read the term and the definition here. The deck at the top of this page is optional.
- Restriction endonuclease
- An enzyme that recognizes a specific palindromic DNA sequence and cleaves the phosphodiester backbone, producing sticky or blunt ends used in molecular cloning.
- Polymerase chain reaction
- An in vitro method that amplifies a DNA segment through repeated cycles of denaturation, primer annealing, and extension by a thermostable DNA polymerase.
- Michaelis constant Km
- The substrate concentration at which an enzyme-catalyzed reaction reaches half its maximum velocity; a lower Km indicates higher apparent substrate affinity.
- Sanger sequencing
- A DNA sequencing method that uses dideoxynucleotides to terminate chain elongation at specific bases, producing fragments separated by capillary electrophoresis.
- CRISPR-Cas9
- A genome-editing system in which a guide RNA directs the Cas9 endonuclease to a complementary DNA target, creating a double-strand break repaired by NHEJ or HDR.
- First law of thermodynamics
- The principle that the change in internal energy of a system equals the heat added to the system plus the work done on it: ΔU = q + w.
- Gibbs free energy
- A thermodynamic potential defined as G = H − TS; at constant temperature and pressure, a process is spontaneous when ΔG is negative.
- Arrhenius equation
- The relation k = A e^(−Ea/RT) describing how the rate constant k depends on activation energy Ea and temperature T, with pre-exponential factor A.
- Henderson–Hasselbalch equation
- The expression pH = pKa + log([A⁻]/[HA]) used to calculate the pH of a buffer from the acid dissociation constant and conjugate base-to-acid ratio.
- Nernst equation
- The equation E = E° − (RT/nF) ln Q relating cell potential to standard potential and reaction quotient; at 298 K it becomes E° − (0.0592/n) log Q.
- Price elasticity of demand
- The percentage change in quantity demanded divided by the percentage change in price; demand is elastic when the absolute value exceeds one.
- Lerner index
- A measure of monopoly power equal to (P − MC)/P, which equals the reciprocal of the absolute price elasticity of demand at the profit-maximizing output.
- GDP expenditure identity
- Gross domestic product equals consumption plus investment plus government spending plus net exports (exports minus imports) for a given period.
- Quantity theory of money
- The relation MV = PY stating that money supply times velocity equals price level times real output; in the long run, money growth tends to raise prices proportionally.
- Comparative advantage
- The ability of a country to produce a good at a lower opportunity cost than another country, forming the basis for mutually beneficial specialization and trade.
- Mohs hardness scale
- A relative scale from 1 (talc) to 10 (diamond) ranking minerals by resistance to scratching; a mineral scratches those with lower numbers.
- Bowen's reaction series
- The sequence in which silicate minerals crystallize from cooling magma, from olivine and pyroxene at high temperature to quartz and muscovite at low temperature.
- Seismic P and S waves
- Body waves generated by earthquakes: P waves are compressional and travel faster; S waves are shear waves that cannot pass through liquids, revealing a liquid outer core.
- Moment magnitude Mw
- An earthquake magnitude scale based on seismic moment M₀, defined as Mw = (2/3) log₁₀ M₀ − 6.07, where M₀ is measured in newton-meters.
- Isostasy
- The state of gravitational balance in which the lithosphere floats on the denser asthenosphere; Airy and Pratt models explain crustal root and density variations.
- Rolle's theorem
- If a function is continuous on a closed interval, differentiable on the open interval, and equal at the endpoints, then its derivative vanishes somewhere inside.
- Mean value theorem
- For a function continuous on [a,b] and differentiable on (a,b), there exists a point c where the derivative equals the average rate of change over the interval.
- Taylor series
- An expansion of a function about a point a as the infinite sum of its derivatives at a multiplied by powers of (x − a) divided by factorials.
- Eigenvalue equation
- For a square matrix A, a scalar λ and nonzero vector v satisfy Av = λv; λ is found from det(A − λI) = 0.
- Cauchy–Riemann equations
- The pair u_x = v_y and u_y = −v_x relating real and imaginary parts of a complex function; together with continuity of partials they imply analyticity.
- Bayes' theorem
- The rule P(A|B) = P(B|A)P(A)/P(B) that updates the probability of an event given new evidence, using prior and conditional probabilities.
- Central limit theorem
- For independent identically distributed variables with finite mean and variance, the standardized sample mean converges in distribution to a standard normal as sample size grows.
- Unbiased estimator
- A statistic whose expected value equals the parameter being estimated; for example, the sample variance with denominator n − 1 is unbiased for population variance.
- Maximum likelihood estimator
- The parameter value that maximizes the likelihood function of the observed sample, often obtained by setting the derivative of the log-likelihood to zero.
- Type I and Type II errors
- In hypothesis testing, Type I error is rejecting a true null hypothesis with probability α; Type II error is failing to reject a false null with probability β.
- Simple harmonic motion
- Oscillatory motion described by x(t) = A cos(ωt + φ), where the restoring force is proportional to displacement; angular frequency ω depends on the system.
- Photoelectric effect
- The emission of electrons from a material when light exceeds a threshold frequency; maximum kinetic energy equals hf minus the work function.