Iraqi Board Internal Medicine flashcards
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- STEMI reperfusion window
- Primary percutaneous coronary intervention is preferred if it can be delivered within 120 minutes of first medical contact; otherwise fibrinolysis is given within 12 hours of symptom onset when no contraindication exists.
- CHA2DS2-VASc anticoagulation threshold
- In atrial fibrillation, oral anticoagulation is indicated when the CHA2DS2-VASc score is at least 2 in men or at least 3 in women, after considering bleeding risk.
- Severe aortic stenosis criteria
- Severe aortic stenosis is defined by an aortic valve area below 1.0 cm², a mean gradient of at least 40 mmHg, or a peak velocity of at least 4.0 m/s.
- CURB-65 score components
- CURB-65 assigns one point each for confusion, urea above 7 mmol/L, respiratory rate at least 30/min, low systolic or diastolic blood pressure, and age at least 65 years.
- Light criteria exudate
- Pleural fluid is an exudate if pleural/serum protein exceeds 0.5, pleural/serum lactate dehydrogenase exceeds 0.6, or pleural lactate dehydrogenase exceeds two-thirds the upper normal serum value.
- Tension pneumothorax management
- Tension pneumothorax requires immediate needle decompression without waiting for imaging, followed by tube thoracostomy; hypotension and tracheal deviation may be present.
- SAAG in ascites
- Serum-ascites albumin gradient of at least 1.1 g/dL indicates portal hypertension, whereas a lower gradient suggests peritoneal carcinomatosis, tuberculosis, pancreatitis, or nephrotic ascites.
- Spontaneous bacterial peritonitis threshold
- Spontaneous bacterial peritonitis is diagnosed when ascitic fluid polymorphonuclear cell count is at least 250 cells per mm³; empiric third-generation cephalosporin is started and albumin added for renal impairment.
- Acute pancreatitis diagnostic rule
- Acute pancreatitis is diagnosed when at least two of three are present: typical epigastric pain, lipase or amylase above three times the upper limit, and characteristic imaging findings.
- KDIGO acute kidney injury
- Acute kidney injury is defined by a serum creatinine rise of at least 0.3 mg/dL within 48 hours, at least 1.5 times baseline within 7 days, or urine output below 0.5 mL/kg/hour for 6 hours.
- Hyperkalemia emergency treatment
- Intravenous calcium stabilizes the myocardium; insulin with glucose, inhaled salbutamol, and sodium bicarbonate shift potassium intracellularly; dialysis removes potassium in refractory or renal failure cases.
- SIADH diagnostic pattern
- SIADH causes euvolemic hypotonic hyponatremia with urine osmolality above 100 mOsm/kg and urine sodium usually above 30 mmol/L, after excluding hypothyroidism, adrenal insufficiency, and diuretics.
- Diabetic ketoacidosis diagnostic triad
- Diabetic ketoacidosis requires hyperglycemia, ketonemia or ketonuria, and metabolic acidosis with pH below 7.3 or bicarbonate below 18 mmol/L; fluids, insulin, and potassium replacement are core treatment.
- Thyroid storm treatment sequence
- Thyroid storm is treated with a beta-blocker, a thionamide, iodine at least one hour after the thionamide, glucocorticoids, supportive care, and treatment of the precipitating illness.
- Primary aldosteronism screening
- Primary aldosteronism is screened by an elevated plasma aldosterone-to-renin ratio in hypertension, especially with hypokalemia; confirmatory testing and adrenal imaging or vein sampling follow.
- Iron deficiency laboratory pattern
- Iron deficiency shows low ferritin, low mean corpuscular volume, low transferrin saturation below 20 percent, and high total iron-binding capacity; ferritin may be normal during inflammation.
- Neutropenic fever definition
- Neutropenic fever is a single temperature of at least 38.3°C or at least 38.0°C for one hour in a patient with absolute neutrophil count below 500 cells/mm³; empiric antibiotics start within 60 minutes.
- Heparin-induced thrombocytopenia features
- Heparin-induced thrombocytopenia causes a platelet fall exceeding 50 percent, often with thrombosis, typically 5 to 10 days after heparin; heparin is stopped and a non-heparin anticoagulant started.
- SLE specific autoantibodies
- Anti-double-stranded DNA and anti-Smith antibodies are highly specific for systemic lupus erythematosus; antinuclear antibody is sensitive but not specific, and complement levels fall during active disease.
- Gout crystal finding
- Gout is confirmed by needle-shaped, negatively birefringent monosodium urate crystals in joint fluid; pseudogout shows rhomboid, positively birefringent calcium pyrophosphate crystals.
- Anaphylaxis first-line treatment
- Anaphylaxis is treated first with intramuscular epinephrine 0.5 mg of 1:1000 solution into the anterolateral thigh, repeated every 5 to 15 minutes as needed, plus fluids.
- Septic shock definition
- Septic shock is sepsis with vasopressor need to maintain mean arterial pressure at least 65 mmHg and lactate above 2 mmol/L despite adequate fluid resuscitation.
- Bacterial meningitis CSF pattern
- Bacterial meningitis typically shows low cerebrospinal fluid glucose, high protein, and neutrophil predominance; empiric ceftriaxone plus vancomycin is started, with dexamethasone in pneumococcal disease.
- HIV opportunistic prophylaxis thresholds
- When CD4 count is below 200 cells/mm³, co-trimoxazole prevents Pneumocystis pneumonia; below 50 cells/mm³, azithromycin prevents disseminated Mycobacterium avium complex; antiretroviral therapy starts regardless of CD4.
- Stroke thrombolysis eligibility
- Intravenous thrombolysis is considered within 4.5 hours of ischemic stroke onset after excluding hemorrhage and lowering blood pressure below 185/110 mmHg; thrombectomy is considered for large vessel occlusion.
- Status epilepticus treatment ladder
- Status epilepticus is treated first with a benzodiazepine, then levetiracetam, fosphenytoin, or valproate; refractory cases require intubation and continuous propofol or midazolam.
- Guillain-Barré syndrome features
- Guillain-Barré syndrome causes ascending flaccid weakness and areflexia with albuminocytologic dissociation in cerebrospinal fluid; treatment is intravenous immunoglobulin or plasma exchange, with monitoring of vital capacity.
- Delirium core features
- Delirium is an acute, fluctuating disturbance of attention and awareness caused by an underlying medical condition, medication, or withdrawal; treatment targets the cause, with antipsychotics reserved for severe distress.
- Alcohol withdrawal treatment
- Alcohol withdrawal is managed with symptom-triggered benzodiazepines guided by a withdrawal scale; thiamine is given before glucose in malnourished patients to prevent Wernicke encephalopathy.
- ARDS Berlin definition
- Acute respiratory distress syndrome is acute onset within one week, bilateral opacities not fully explained by heart failure, and PaO2/FiO2 ratio at most 300 on positive end-expiratory pressure at least 5.
- ACLS shockable rhythm sequence
- For ventricular fibrillation or pulseless ventricular tachycardia, deliver immediate defibrillation, start CPR, give epinephrine 1 mg every 3 to 5 minutes, and consider amiodarone after the third shock.
- Parkland burn formula
- The Parkland formula gives 4 mL of lactated Ringer per kg body weight per percent total body surface area burned in 24 hours, with half given in the first 8 hours from injury.