Pericardial and Myocardial Disease
Items test the distinction between pericarditis and infarction, the bedside recognition of tamponade, the haemodynamics of constriction, and the modern work-up of myocarditis with cardiac magnetic resonance.
Acute pericarditis
- Diagnostic triad: pleuritic chest pain relieved by sitting forward, pericardial friction rub, and diffuse ST elevation with PR depression.
- Treat with NSAID plus colchicine; restrict exercise; reserve corticosteroids for contraindications to NSAIDs because they increase recurrence.
- High-risk features requiring admission: fever above 38 degrees, subacute course, large effusion, tamponade, or immunosuppression.
Tamponade and constriction
- Tamponade: hypotension, distended neck veins, muffled heart sounds, pulsus paradoxus above 10 mmHg, electrical alternans, and diastolic collapse of right-sided chambers on echo; treat with pericardiocentesis.
- Constrictive pericarditis: Kussmaul sign, pericardial knock, septal bounce, annulus reversus with medial e-prime exceeding lateral, and equalisation of diastolic pressures; treat with pericardiectomy.
Myocarditis
- Viral prodrome with chest pain, troponin rise, and arrhythmia; ST changes without regional distribution.
- Cardiac MRI uses Lake Louise criteria: myocardial oedema on T2 mapping plus non-ischaemic late gadolinium enhancement.
- Treat heart failure and arrhythmia; avoid strenuous exercise for 3-6 months; giant cell myocarditis needs immunosuppression and early transplant assessment.
Worked example
A 28-year-old with fever and sharp chest pain has diffuse ST elevation, PR depression, troponin mildly elevated, and a small effusion. This is myopericarditis, not STEMI: give ibuprofen plus colchicine, avoid anticoagulation, and do not take him to the catheter laboratory.
Traps
- Anticoagulating presumed pericarditis can cause haemorrhagic effusion.
- Post-infarction pericarditis and Dressler syndrome occur at different times after the event.
- A normal ECG does not exclude tamponade; look for pulsus paradoxus and echo signs.