Kuwait MOH Doctor Exam flashcards
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- CURB-65
- Pneumonia severity score: confusion, urea >7 mmol/L, respiratory rate ≥30, blood pressure systolic <90 or diastolic ≤60, age ≥65; each scores one point.
- DKA management
- IV saline, insulin infusion after potassium >3.3 mmol/L, add dextrose when glucose <11.1 mmol/L; monitor potassium and anion gap; avoid rapid osmolar shifts.
- Heart failure four pillars
- For HFrEF: ARNI/ACEi/ARB, evidence-based beta-blocker, mineralocorticoid receptor antagonist, and SGLT2 inhibitor; each reduces mortality and should be titrated to target dose.
- Alvarado score
- Appendicitis score: migration of pain, anorexia, nausea/vomiting, right iliac fossa tenderness, rebound tenderness, fever, leukocytosis, left shift; score ≥7 suggests appendicitis.
- Trauma primary survey
- Airway with cervical spine protection, Breathing, Circulation with hemorrhage control, Disability (GCS), Exposure/environment; adjuncts include FAST, chest and pelvis X-ray.
- Femoral hernia risk
- Femoral hernias have the highest risk of strangulation among groin hernias; early elective repair is recommended, and tender or irreducible hernias need urgent surgery.
- Pediatric dehydration plan C
- For severe dehydration: IV Ringer's lactate 100 mL/kg; give 30 mL/kg bolus first, then reassess; continue according to WHO plan C with frequent monitoring.
- Kawasaki disease criteria
- Fever ≥5 days plus 4 of 5: conjunctivitis, oral changes, rash, extremity changes, cervical lymphadenopathy; treat with IVIG 2 g/kg and aspirin; echocardiography for coronary aneurysms.
- Simple febrile seizure
- Generalized seizure lasting <15 minutes, occurring once in 24 hours, in a child aged 6 months to 5 years; no routine lumbar puncture if meningeal signs are absent.
- Preeclampsia severe features
- Blood pressure ≥160/110, platelets <100,000, elevated liver enzymes, pulmonary edema, visual or cerebral symptoms, or renal insufficiency; requires magnesium sulfate and delivery planning.
- Postpartum hemorrhage
- Uterine atony is the most common cause; treat with uterotonics, bimanual massage, tranexamic acid within 3 hours, and balloon tamponade or surgery if refractory.
- Gestational diabetes screening
- 75 g OGTT at 24–28 weeks: fasting ≥5.1 mmol/L, 1-hour ≥10.0, or 2-hour ≥8.5 mmol/L; lifestyle first, then insulin or metformin if targets are not met.
- Hypertension first-line drugs
- Thiazide-type diuretics, ACE inhibitors or ARBs, and calcium channel blockers are first-line for hypertension; choice depends on comorbidities and patient characteristics.
- Type 2 diabetes add-on
- Add SGLT2 inhibitor or GLP-1 receptor agonist for atherosclerotic cardiovascular disease, heart failure, or chronic kidney disease; metformin remains first-line unless contraindicated.
- Antibiotic stewardship
- Do not prescribe antibiotics for viral upper respiratory infections, acute bronchitis, or uncomplicated rhinosinusitis without criteria; use delayed prescriptions when appropriate.
- Anaphylaxis treatment
- IM epinephrine 0.3–0.5 mg (1:1000) into the anterolateral thigh, repeat every 5–15 minutes; adjuncts include IV fluids, oxygen, bronchodilators, and antihistamines; observe for biphasic reaction.
- Cardiac arrest CPR
- Compressions at 100–120/min, depth 5–6 cm, full recoil, minimize interruptions; defibrillate shockable rhythms immediately; epinephrine 1 mg every 3–5 minutes.
- Sepsis bundle
- Measure lactate, obtain cultures, give broad-spectrum antibiotics within 1 hour, and 30 mL/kg crystalloid for hypotension or lactate ≥4 mmol/L; reassess perfusion.
- Status epilepticus
- Benzodiazepine first-line (lorazepam 0.1 mg/kg IV, diazepam, or midazolam IM); if persistent, second-line antiepileptic such as levetiracetam, valproate, or fosphenytoin.
- Major depressive episode
- At least five symptoms for two weeks including depressed mood or anhedonia; assess suicide risk; first-line psychotherapy or SSRI; continue treatment 6–12 months after remission.
- Serotonin syndrome
- Clonus, hyperreflexia, agitation, and hyperthermia after serotonergic agents; stop offending drugs, supportive care, benzodiazepines, and cyproheptadine for moderate-severe cases.
- Neuroleptic malignant syndrome
- Rigidity, fever, autonomic instability, altered mental status, and elevated CK after dopamine antagonists; stop the agent, provide supportive care, and consider dantrolene or bromocriptine.
- Alcohol withdrawal
- Use CIWA-Ar guided therapy with benzodiazepines; give thiamine before glucose to prevent Wernicke encephalopathy; monitor for delirium tremens and autonomic instability.
- Cardiac output
- Cardiac output equals heart rate multiplied by stroke volume; stroke volume depends on preload, afterload, and contractility; the Fick principle estimates output from oxygen consumption.
- Henderson-Hasselbalch equation
- pH = 6.1 + log([HCO3−]/(0.03 × PaCO2)); used to assess acid-base status; Winter's formula predicts expected PaCO2 in metabolic acidosis.
- First-order kinetics
- Half-life t½ = 0.693 × volume of distribution / clearance; steady state is reached in about 4–5 half-lives; loading dose = volume of distribution × target concentration / bioavailability.
- Informed consent
- Requires capacity, adequate information about diagnosis, risks, benefits, and alternatives, and voluntariness; document the discussion; emergency exception applies when no surrogate is available.
- Capacity assessment
- Patient can understand information, appreciate consequences, reason, and communicate a choice; capacity is decision-specific and presumed unless clinical evidence suggests otherwise.
- Confidentiality exceptions
- Disclosure without consent is permitted for reportable communicable diseases, imminent harm to self or others, and suspected child or elder abuse, as required by law.
- Sensitivity and specificity
- Sensitivity = TP/(TP+FN); specificity = TN/(TN+FP); positive predictive value depends on disease prevalence; screening programs require high sensitivity and acceptable PPV.
- Herd immunity threshold
- Threshold = 1 − 1/R0; for measles with R0 12–18, about 92–95% immunity is needed; for influenza with R0 ~1.3, about 25% is needed.
- Levels of prevention
- Primary prevents onset (vaccination), secondary detects early disease (screening), and tertiary limits disability (rehabilitation); each level targets a different stage of disease.