LGCSE Biology (0180) study materials
LGCSE Biology (0180) study resources

LGCSE Biology (0180) key terms

LGCSE Biology (0180) · Get comfortable with the vocabulary.

Cell membrane

A thin, flexible layer of lipid and protein surrounding every cell. It controls which substances enter and leave, allowing small molecules through while restricting others.

Related: Diffusion, Osmosis
Mitochondrion

An organelle with a folded inner membrane where aerobic respiration takes place. It releases energy from glucose, so cells that need lots of energy contain many of them.

Related: Aerobic respiration, Enzyme
Chloroplast

A green organelle found in plant cells that contains chlorophyll and carries out photosynthesis, trapping light energy to make glucose from carbon dioxide and water.

Related: Photosynthesis, Limiting factor
Diffusion

The net movement of particles from a region of higher concentration to a region of lower concentration, caused by random motion and requiring no energy from the cell.

Related: Osmosis, Surface area to volume ratio
Osmosis

The movement of water molecules through a partially permeable membrane from a dilute solution to a more concentrated one, down a water potential gradient.

Related: Diffusion, Cell membrane
Enzyme

A protein that speeds up a specific reaction by binding its substrate at an active site. Enzymes are biological catalysts and are affected by temperature and pH.

Related: Active site, Denaturation
Active site

The small region of an enzyme where the substrate binds. Its shape is complementary to the substrate, so each enzyme catalyses only particular reactions.

Related: Enzyme, Denaturation
Denaturation

Loss of the precise three-dimensional shape of a protein such as an enzyme, usually caused by high temperature or extreme pH, so the active site no longer fits the substrate.

Related: Enzyme, Active site
Aerobic respiration

The breakdown of glucose using oxygen to release energy, producing carbon dioxide and water. It yields far more energy per glucose molecule than anaerobic respiration.

Related: Anaerobic respiration, Mitochondrion
Anaerobic respiration

Release of energy from glucose without oxygen. In human muscle it produces lactic acid; in yeast it produces ethanol and carbon dioxide, and less energy is released overall.

Related: Aerobic respiration, Fermentation
Photosynthesis

The process in which plants use light energy trapped by chlorophyll to convert carbon dioxide and water into glucose, releasing oxygen as a by-product.

Related: Chloroplast, Limiting factor
Limiting factor

The environmental condition in shortest supply that holds back the rate of a process such as photosynthesis, for example light intensity, carbon dioxide concentration or temperature.

Related: Photosynthesis, Enzyme
Surface area to volume ratio

A measure comparing an organism's or structure's outer surface with its internal volume. A high ratio speeds exchange; large organisms need specialised exchange surfaces and transport systems.

Related: Diffusion, Alveolus
Alveolus

One of many tiny air sacs in the lungs. Their huge combined surface area, thin walls and rich blood supply make them efficient sites of gas exchange.

Related: Diffusion, Surface area to volume ratio
Villus

A finger-like projection of the small intestine lining. Villi increase surface area for absorption of digested food and contain capillaries and a lacteal.

Related: Enzyme, Bile
Bile

A green fluid made in the liver and stored in the gall bladder. It emulsifies fats into small droplets, increasing their surface area for enzyme action, and neutralises stomach acid.

Related: Villus, Enzyme
Transpiration

Loss of water vapour from the leaves of a plant, mainly through stomata. It draws water up the xylem and is affected by light, temperature, humidity and wind.

Related: Stoma, Xylem
Xylem

Plant tissue of hollow, dead, lignified cells that transports water and dissolved minerals upward from the roots to the leaves and helps support the plant.

Related: Transpiration, Stoma
Stoma

A small pore in the leaf epidermis, surrounded by two guard cells, through which gases and water vapour pass. Guard cells open and close it depending on conditions.

Related: Transpiration, Xylem
Homeostasis

The maintenance of a stable internal environment within narrow limits, for example controlling blood glucose, body temperature and water balance despite external change.

Related: Negative feedback, Insulin
Negative feedback

A control mechanism in which a change away from a set point triggers a response that reverses the change, restoring the original level. It keeps conditions such as temperature steady.

Related: Homeostasis, Insulin
Insulin

A hormone secreted by the pancreas when blood glucose rises. It causes liver and muscle cells to take up glucose and store it as glycogen, lowering blood glucose.

Related: Homeostasis, Negative feedback
Reflex action

A rapid, automatic response to a stimulus that does not involve conscious thought, using a pathway called a reflex arc from receptor to effector.

Related: Synapse, Negative feedback
Synapse

A tiny gap between two neurones, or between a neurone and an effector. A chemical neurotransmitter diffuses across it to carry the impulse onward.

Related: Reflex action, Diffusion
Gene

A short section of DNA that codes for a particular protein or characteristic. Genes occur in pairs, one inherited from each parent, and can exist as different alleles.

Related: Allele, Genotype
Allele

One of the alternative forms of a gene, such as the tall or short form for plant height. Alleles may be dominant or recessive and determine the phenotype shown.

Related: Gene, Genotype
Genotype

The combination of alleles an organism carries for a gene, for example homozygous dominant, heterozygous or homozygous recessive. It is written with paired letters.

Related: Allele, Phenotype
Phenotype

The observable characteristic of an organism, such as eye colour or seed shape, resulting from its genotype interacting with the environment.

Related: Genotype, Allele
Mutation

A random change in the base sequence of DNA. Mutations may have no effect, alter the protein produced, or create new alleles on which natural selection can act.

Related: Gene, Natural selection
Natural selection

The process by which individuals with inherited features better suited to their environment survive and reproduce more, so those alleles become more common over generations.

Related: Mutation, Adaptation
Adaptation

An inherited feature of a species that improves its chance of survival and reproduction in a particular habitat, such as a thick coat or a streamlined body.

Related: Natural selection, Mutation
Food chain

A diagram showing the direction of energy transfer from one organism to the next, beginning with a producer and using arrows to show what eats what.

Related: Producer, Trophic level
Producer

An organism, usually a green plant or alga, that makes its own food by photosynthesis and so forms the starting point of every food chain.

Related: Food chain, Photosynthesis
Trophic level

A feeding position in a food chain, such as producer, primary consumer or secondary consumer. Energy and biomass generally decrease at each successive level.

Related: Food chain, Producer
Pollination

The transfer of pollen from the anther of a flower to the stigma, either within the same flower or between flowers, bringing male gametes to the female part.

Related: Fertilisation, Gamete
Fertilisation

The fusion of a male and female gamete to form a zygote containing the full chromosome number, restoring the diploid number after the halving that occurs in meiosis.

Related: Gamete, Pollination
Gamete

A specialised sex cell, such as a sperm, egg or pollen grain, that carries half the normal chromosome number and joins with another gamete at fertilisation.

Related: Fertilisation, Pollination
Controlled variable

A factor that is deliberately kept the same throughout an investigation so that it cannot affect the outcome, making the results fair and comparable.

Related: Reliability, Fair test
Reliability

The extent to which repeated measurements give consistent results. It is improved by repeating readings, taking a larger sample and identifying and removing anomalous values.

Related: Controlled variable, Fair test
Fair test

An experiment in which only the independent variable is changed, all other relevant factors are controlled, and the dependent variable is measured accurately.

Related: Controlled variable, Reliability