MT POST study materials
MT POST study resources

MT POST key terms

MT POST · Get comfortable with the vocabulary.

Reference Interval

The range of test results expected in a healthy population, usually spanning the central 95 percent of values, used to judge whether a patient result is normal or abnormal.

Related: Critical Value, Delta Check, Standard Deviation
Critical Value

A result far outside the reference interval that may signal immediate danger to the patient and requires prompt notification of the responsible clinician, with the notification documented.

Related: Reference Interval, Delta Check
Delta Check

A quality rule that compares a patient's current result with a previous result for the same test and flags the specimen when the change exceeds a set limit.

Related: Reference Interval, Critical Value
Standard Deviation

A statistical measure of how widely values spread around their mean; in the laboratory it describes the dispersion of control results and underpins precision assessment.

Related: Coefficient of Variation, Levey-Jennings Chart
Coefficient of Variation

The standard deviation expressed as a percentage of the mean, allowing precision to be compared across tests or analyte levels with different units and magnitudes.

Related: Standard Deviation, Levey-Jennings Chart
Levey-Jennings Chart

A control chart that plots quality control results over time against mean and standard deviation limits so trends, shifts, and random error become visible.

Related: Westgard Rules, Standard Deviation
Westgard Rules

A set of statistical rules, such as 1-2s, 1-3s, 2-2s, R-4s, and 4-1s, used to decide whether control results indicate acceptable performance or a run should be rejected.

Related: Levey-Jennings Chart, Coefficient of Variation
Proficiency Testing

An external program that sends unknown specimens to many laboratories and compares each laboratory's results with peer results to assess ongoing testing accuracy.

Related: External Quality Assessment, Calibration
External Quality Assessment

A broader interlaboratory comparison scheme, of which proficiency testing is one type, used to verify performance against other laboratories and identify systematic bias.

Related: Proficiency Testing
Calibration

The process of adjusting an instrument using materials of known value so that measured signals correspond correctly to true analyte concentrations.

Related: Proficiency Testing, Analytical Sensitivity
Analytical Sensitivity

The ability of a method to detect small amounts of an analyte, often described by the lowest concentration that can be reliably distinguished from zero.

Related: Analytical Specificity, Calibration
Analytical Specificity

The ability of a method to measure only the intended analyte without interference from other substances present in the specimen.

Related: Analytical Sensitivity, Hemolysis
Hemolysis

Rupture of red blood cells that releases hemoglobin into the specimen, which can discolor serum or plasma and interfere with many chemistry and immunoassay measurements.

Related: Analytical Specificity, Specimen Rejection
Specimen Rejection

Refusal to test a sample that fails acceptance criteria, such as incorrect tube type, insufficient volume, unlabeled container, or gross hemolysis, with the reason documented.

Related: Hemolysis, Chain of Custody
Chain of Custody

A documented, unbroken record of who collected, handled, stored, and received a specimen, required for forensic, workplace, and other legally defensible testing.

Related: Specimen Rejection
Phlebotomy

The collection of blood by venipuncture or capillary puncture using aseptic technique, correct order of draw, and appropriate tube selection for the tests ordered.

Related: Order of Draw, Anticoagulant
Order of Draw

The recommended sequence for filling blood collection tubes so that additive carryover between tubes does not contaminate specimens and invalidate test results.

Related: Phlebotomy, Anticoagulant
Anticoagulant

A substance such as EDTA, citrate, or heparin added to a collection tube to prevent blood clotting so that whole blood or plasma can be analyzed.

Related: Order of Draw, Serum
Serum

The fluid remaining after blood has clotted and the clot has been removed, containing no fibrinogen and used for many chemistry and immunology tests.

Related: Anticoagulant
Standard Precautions

Infection control practices applied to every patient regardless of diagnosis, including hand hygiene, gloves, gowns, and eye protection when exposure to body fluids is likely.

Related: Personal Protective Equipment, Biohazard
Personal Protective Equipment

Barrier items such as gloves, gowns, masks, and eye shields worn to protect the worker from contact with blood, body fluids, and other hazardous materials.

Related: Standard Precautions, Biohazard
Biohazard

Any biological material, including blood, tissue, and cultures, that poses a risk of infection to people or the environment and requires safe handling and disposal.

Related: Standard Precautions, Sharps Container
Sharps Container

A puncture-resistant, closable, labeled receptacle used to discard needles, lancets, and other sharp items immediately after use to prevent needlestick injuries.

Related: Biohazard, Needlestick Injury
Needlestick Injury

Accidental penetration of the skin by a used needle or sharp, requiring immediate first aid, reporting, and evaluation for post-exposure prophylaxis and follow-up testing.

Related: Sharps Container, Standard Precautions
CLIA

The United States Clinical Laboratory Improvement Amendments, which set federal quality standards for laboratory testing and classify tests by complexity.

Related: Proficiency Testing, Waived Test
Waived Test

A simple test classified as low risk under CLIA and cleared for use by untrained operators, still requiring adherence to manufacturer instructions and good practice.

Related: CLIA
HIPAA

The United States Health Insurance Portability and Accountability Act, which protects the privacy and security of identifiable patient health information, including laboratory results.

Related: Confidentiality, Informed Consent
Confidentiality

The ethical and legal duty to keep patient information private and share it only with those who have a legitimate need to know for care or required reporting.

Related: HIPAA, Informed Consent
Informed Consent

A patient's voluntary agreement to a procedure or test after receiving an explanation of its purpose, risks, benefits, and alternatives in understandable terms.

Related: Confidentiality
Accuracy

How close a measured result is to the true value of the analyte, reflecting freedom from systematic error or bias in the measurement process.

Related: Precision, Calibration
Precision

How closely repeated measurements of the same sample agree with one another, reflecting random error rather than closeness to the true value.

Related: Accuracy, Coefficient of Variation
Leukocyte

A white blood cell involved in immune defense; its concentration and differential distribution in blood help identify infection, inflammation, and hematologic disease.

Related: Hemoglobin, Hematocrit
Hemoglobin

The iron-containing protein in red blood cells that carries oxygen; its concentration is a primary measure for detecting and classifying anemia.

Related: Hematocrit, Leukocyte
Hematocrit

The percentage of blood volume occupied by red blood cells, usually obtained by centrifugation or calculated from red cell count and mean cell volume.

Related: Hemoglobin, Leukocyte
Glomerular Filtration Rate

An estimate of how much blood the kidneys filter per minute, commonly calculated from serum creatinine and used to stage chronic kidney disease.

Related: Reference Interval
Turnaround Time

The elapsed time from specimen receipt or order entry to result reporting, a key operational and service metric monitored by laboratories.

Related: Specimen Rejection
Biosafety Level

A graded set of containment practices and facility requirements, from BSL-1 to BSL-4, matched to the risk of the infectious agents being handled.

Related: Biohazard, Standard Precautions