MAB Registration Exam case studies
MAB Registration Exam · Put your knowledge to work in context.
The MAB Registration Exam (also described as the Medical Affairs Board Registration Examination or MAB Certification Exam) is a multiple-choice credential aimed at professionals working in, or moving into, medical affairs within the life sciences industry. It is designed for medical science liaisons, medical information specialists, medical advisors, publication and medical communications staff, and adjacent roles such as regulatory, pharmacovigilance, and market access professionals who need a structured grasp of how medical affairs operates. The MAB Registration Exam case studies are 5 cases and about 2,958 words.
1Field Medical Request for an Off-Label Combination IIT
Elena Marsh, a community oncologist in a 12-physician practice, emails her company's MSL, Priya, requesting $75,000 and data-extraction support for a single-center retrospective chart review of 40 patients. The proposal combines the company's approved FGFR2 inhibitor with gemcitabine/cisplatin in first-line intrahepatic cholangiocarcinoma, an off-label combination, and would be conducted by Dr.
656 words, about 3 min2Payer Request for an Unpublished Network Meta-Analysis
A medical information specialist at a specialty neurology company receives a portal request from the clinical pharmacist chairing a regional health plan's P&T committee. The plan covers 480,000 members and is reviewing prior authorization criteria for the company's anti-CGRP monoclonal antibody.
609 words, about 3 min3Conference Abstract Signals a Serious Cutaneous Reaction
On Monday, 3 March, an MSL forwards to the safety department an abstract from a regional dermatology meeting. The abstract describes a 64-year-old woman with plaque psoriasis who developed biopsy-confirmed Stevens-Johnson syndrome 18 days after starting the company's IL-23 inhibitor; she was hospitalized for 11 days and recovered.
598 words, about 3 min4Subgroup Spin and Authorship in a Failed Phase 3 Trial
A medical writer is drafting a manuscript for a Phase 3 trial of a chronic kidney disease drug. The trial randomized 612 patients; the primary endpoint (eGFR slope over 24 months) missed significance (p=0.11).
580 words, about 3 min5Budget Impact Model for a One-Time Gene Therapy
A US regional payer with 1.2 million members asks the medical affairs HEOR team to review a budget impact model for a one-time gene therapy for hemophilia B. The list price is $2.8 million per infusion.
515 words, about 3 min