NIOSH SSS study materials
NIOSH SSS study resources

NIOSH SSS cheat sheet

NIOSH SSS · Keep the key ideas within reach.

Quick reference

Indications for Spirometry and Contraindications to Testing

  • Indications: detect airflow obstruction, confirm COPD/asthma diagnosis, grade severity, monitor disease progression or treatment response, assess preoperative pulmonary risk, evaluate dyspnea or chronic cough, and screen for impairment in occupational lung-disease surveillance.

  • Relative contraindications to forced expiratory maneuvers: recent myocardial infarction, thoracic, abdominal, or ocular surgery, pneumothorax, hemoptysis, thoracic or abdominal aneurysm, and unstable cardiovascular status.

  • Absolute contraindications include acute illness with impaired coordination and conditions where a forced vital capacity could cause harm, such as recent pneumothorax or acute myocardial infarction.

  • Defer testing when the participant has active pulmonary tuberculosis, hemoptysis of unknown origin, or acute respiratory infection with fever until resolved.

  • Bronchospasm after a recent bronchial challenge or methacholine test is a reason to delay testing; wait until airway tone has returned to baseline.

  • Pregnancy is not an absolute contraindication; forced maneuvers are generally acceptable but vigorous effort and Valsalva may warrant caution and clinical judgment.

  • Document the indication and any contraindication review before testing so the interpretation can be contextualized to the referral question.

  • Spirometry alone cannot diagnose asthma; a normal baseline does not rule out reversible airway disease, so bronchodilator response or challenge testing may be indicated.

Quick reference

Spirometer Performance, Calibration Verification, and Quality Control

  • ATS/ERS 2019 accuracy limits: volume accuracy within ±3.5% of reading or ±0.05 L, whichever is greater; flow accuracy within ±5% of reading or ±0.2 L/s, whichever is greater.

  • Calibration verification with a 3-L syringe is performed daily (at minimum at the start of each testing day) and after cleaning, disinfection, or any sensor or tubing change.

  • The 3-L syringe check must be within ±3.5% (approximately 2.895–3.105 L) at multiple flow rates (low, medium, high) to confirm linearity across flows.

  • Record each calibration check with date, time, syringe volume, measured values, percent error, and the initials of the person performing it; retain records per facility policy.

  • Test the spirometer for leaks before calibration verification; a leak causes low volume readings and invalidates the check.

  • Verify biological control or a healthy nonsmoking staff member periodically as a longitudinal check on system performance, tracking FEV1 and FVC trends over time.

  • Use a syringe with a known volume traceable to a national standard; syringes should be checked for accuracy and replaced if damaged.

  • Time-based checks: confirm the spirometer's clock and sample rate are adequate (volume-time sampling at least 10 Hz recommended for accurate FEV1).

Quick reference

Participant Preparation, Screening, and Test Safety

  • Record age, sex, height (without shoes, to nearest 0.5 cm), and race/ethnicity because reference equations depend on these variables; use measured, not reported, height.

  • Ask about smoking status, current medications (especially bronchodilators), recent illness, and prior lung disease; note time since last bronchodilator dose.

  • Withhold short-acting beta-agonists for at least 4 hours, long-acting beta-agonists for 12 hours, and long-acting anticholinergics for 24 hours when bronchodilator response testing is planned.

  • Explain the maneuver and demonstrate it; use a chair with arms, nose clip, and a seated upright posture with feet flat and head slightly elevated.

  • Loose clothing should be loosened; dentures should be left in if they are well-fitting and aid mouth seal, but removed if they interfere with the seal.

  • Screen for contraindications before every test session and document the review; stop testing if the participant reports chest pain, dizziness, or severe dyspnea.

  • Have a plan for emergencies: oxygen, bronchodilators, and a means to summon help should be available; personnel should be trained in basic life support.

  • Avoid testing immediately after a large meal or vigorous exercise, which can affect effort and comfort.

Quick reference

Coaching and Maneuver Technique for Acceptable Spirometry

  • Instruct: 'Take a deep breath, seal your lips around the mouthpiece, and blast out as hard and fast as you can, then keep going until I tell you to stop.'

  • Demonstrate the maneuver yourself and use enthusiastic, specific coaching during the effort; avoid vague encouragement such as 'breathe normally'.

  • The participant should be seated upright, with the mouthpiece held so the mouth is not obstructed and the head is in a neutral-to-slightly-extended position.

  • Encourage a maximal inhalation to total lung capacity before the forced exhalation; a submaximal inspiration underestimates FVC.

  • Continue coaching the exhalation for at least 6 seconds and until the volume-time curve shows a plateau (no volume change for 1 second) or the participant cannot continue.

  • At least three acceptable maneuvers should be attempted; up to eight may be performed, but stop when reproducibility criteria are met or the participant is fatigued.

  • Use a nose clip and check for leaks at the mouth; observe the participant for proper lip seal and correct technique during each trial.

  • For participants who cough or have a poor start, repeat the maneuver with clearer coaching rather than accepting a technically flawed effort.

Quick reference

Acceptability and Reproducibility Criteria for Spirometry Curves

  • Acceptable maneuver criteria: free of artifacts, no cough in the first second, no glottic closure or variable effort, no leak, and a satisfactory start with a rapid rise to peak flow.

  • End-of-test criteria: the volume-time curve shows a plateau (no change for at least 1 second) or the exhalation lasts at least 6 seconds, or the participant cannot continue.

  • Reproducibility: the two largest FVC values and the two largest FEV1 values should each agree within 0.150 L (150 mL).

  • A maneuver is acceptable if it meets start, end, and artifact criteria; the best FEV1 and best FVC may come from different acceptable maneuvers.

  • Back-extrapolated volume (BEV) should be less than 5% of FVC or 0.150 L, whichever is greater; a larger BEV indicates a hesitant start.

  • Peak expiratory flow should be achieved early; a delayed or rounded peak suggests submaximal effort or a poor start.

  • Report the largest FEV1 and largest FVC from acceptable maneuvers, and use the associated FEV1/FVC ratio from the same maneuver when possible; do not average values.

  • If reproducibility is not achieved after eight maneuvers, report the best values and note the limitation in the interpretation.

Quick reference

Reference Values, Interpretation, and Pattern Recognition

  • Use reference equations appropriate to the population and equipment; the Global Lung Function Initiative (GLI) equations are widely used and provide predicted values and lower limits of normal (LLN).

  • Obstruction is suggested by an FEV1/FVC ratio below the LLN (commonly <0.70 by fixed criterion or below the 5th percentile by GLI) with a reduced FEV1.

  • Restriction is suggested by a reduced FVC with a preserved or increased FEV1/FVC ratio; confirmation requires lung volumes (TLC), as spirometry alone cannot diagnose restriction.

  • Severity grading uses FEV1 percent predicted: mild ≥70%, moderate 60–69%, moderately severe 50–59%, severe 35–49%, and very severe <35%.

  • A bronchodilator response is defined as an increase in FEV1 or FVC of at least 0.200 L and 12% from baseline, meeting both criteria.

  • Compare results to predicted values and LLN rather than percent predicted alone; the LLN accounts for age, sex, height, and ethnicity-related variability.

  • A reduced FEV1 with a reduced FVC and a normal ratio may reflect mixed obstruction and restriction; clinical correlation and further testing are needed.

  • Interpretation should integrate the referral question, symptoms, smoking history, and test quality; a technically poor test should be interpreted with caution.

Quick reference

Recordkeeping, Reporting, and Communication of Results

  • Record participant identifiers, date, time, technologist, spirometer identification, calibration check results, and all maneuver data (flow-volume and volume-time curves).

  • Report FVC, FEV1, FEV1/FVC ratio, FEF25–75%, and PEF with predicted values, LLN, and percent predicted; include the best values and the number of acceptable maneuvers.

  • Document test quality: number of maneuvers attempted, acceptability and reproducibility status, and any deviations from standard technique.

  • Store raw data and curves so results can be re-reviewed; retain records according to institutional and regulatory requirements (often at least 7 years or per local law).

  • Communicate results to the ordering clinician with a clear interpretation and any recommendations for follow-up testing, such as full pulmonary function tests or bronchodilator challenge.

  • Avoid over-interpreting isolated values; report the pattern (obstructive, restrictive, mixed, normal) and severity, and note limitations of the test.

  • Use standardized reporting templates and consistent units (liters, liters per second, percent predicted) to facilitate comparison over time.

  • Ensure confidentiality of health information and share results only with authorized parties per privacy regulations.

Quick reference

Infection Control and Equipment Hygiene

  • Perform hand hygiene before and after participant contact and between participants; use gloves when handling contaminated components.

  • Use a new disposable mouthpiece or filter for each participant; do not reuse single-use items between participants.

  • Clean and disinfect reusable spirometer components (mouthpieces, tubing, valves) according to manufacturer instructions and facility policy after each use or session.

  • Use an EPA-registered disinfectant with the appropriate contact time; follow the label for concentration and duration.

  • Handle bacterial/viral filters according to manufacturer guidance; filters reduce cross-contamination but do not replace cleaning of the spirometer.

  • Clean surfaces and chairs between participants, and ensure adequate ventilation in the testing area.

  • Follow standard precautions and transmission-based precautions; participants with known infectious respiratory illness should be rescheduled or tested with appropriate precautions.

  • Document cleaning and disinfection activities and maintain a log for quality assurance and audit purposes.