NBDE Part I study plan
NBDE Part I · Give each week a clear focus.
8 weeks · About 8 hours per week
Anatomic Sciences
Label from memory the 12 cranial nerves, their foramina of exit, and their major branches
Trace the arterial supply and venous drainage of the head and neck on a blank outline
Recite origins, insertions, actions, and innervation for the muscles of mastication and facial expression
Describe the anatomy of the temporomandibular joint capsule, disc, and ligaments
Identify the bones of the skull, their sutures, and the fossae they form
Your checkpoint
A hand-drawn head-and-neck anatomy sheet with all cranial nerves, vessels, and masticatory muscles labeled at 100% self-checked accuracy
Anatomic Sciences & Biochemistry and Physiology
Explain branchial arch derivatives: skeletal, muscular, and nerve components for arches 1 through 6
Describe the development of the face, palate, and tongue, and name the corresponding congenital defects
Define the structure and ionization behavior of the 20 standard amino acids at physiologic pH
Explain enzyme kinetics using Michaelis-Menten terms and distinguish competitive from noncompetitive inhibition
Summarize the anatomic organization of the spinal cord tracts and the autonomic divisions
Your checkpoint
A 40-question timed mixed set across Domains 1 and 2, scored at 75% or better with every miss rewritten as a corrected fact card
Biochemistry and Physiology
Diagram glycolysis, the citric acid cycle, and oxidative phosphorylation with net ATP and key regulatory enzymes
Compare gluconeogenesis, glycogenolysis, and the pentose phosphate pathway by substrate, tissue, and hormonal control
Explain lipid and amino acid catabolism and where they feed into the central pathways
Describe the hormonal axes of the thyroid, adrenal cortex, pancreas, and gonads with negative feedback loops
Your checkpoint
A one-page metabolic map drawn from memory, then corrected against notes, with all rate-limiting enzymes marked
Biochemistry and Physiology & Microbiology and Pathology
Summarize renal physiology: glomerular filtration, tubular reabsorption and secretion, and acid-base compensation
Describe cardiac cycle phases, pressure-volume relationships, and how cardiac output is regulated
Explain the physiology of nerve conduction, synaptic transmission, and muscle contraction at the sarcomere level
Classify the major bacterial groups by Gram stain, morphology, oxygen requirement, and key virulence factor
Your checkpoint
A 100-question cumulative midterm across Domains 1 through 3, completed under timing, with every error logged by cause (knowledge gap, misread, or guess)
Microbiology and Pathology
Differentiate the major oral and dental plaque organisms by habitat, Gram reaction, and caries or periodontal role
Summarize the structure and replication cycles of the major viral families, including herpesviruses and hepatitis viruses
Explain innate and adaptive immunity, immunoglobulin classes, and complement pathways
Describe the mechanism of action and spectrum for the major antibiotic classes and the basis of resistance
Your checkpoint
A two-column comparison table of at least 25 organisms with their associated oral or systemic disease, written to closed-book accuracy
Microbiology and Pathology & Anatomic Sciences
Sequence the events of acute inflammation, from vascular changes through leukocyte extravasation and resolution
Distinguish reversible from irreversible cell injury and describe the pathways of necrosis versus apoptosis
Classify caries, pulpitis, and periapical pathology by etiology, histologic findings, and clinical sequence
Differentiate benign from malignant neoplasms and name the routes and patterns of metastasis
Describe the gross and microscopic features of common oral mucosal lesions and odontogenic cysts and tumors
Your checkpoint
A written pathology decision tree covering the 15 highest-yield oral lesions, validated against course notes with zero factual contradictions
Dental Anatomy and Occlusion
Draw and describe each anterior and posterior tooth from all five aspects, including pulp chamber and root canal anatomy
State the eruption and exfoliation sequence for both dentitions with approximate ages
Classify Angle's occlusion and identify the features of ideal occlusion in the permanent dentition
Describe mandibular movements of opening, protrusion, and lateral excursion with their condylar and dental relationships
Explain the functional components of an articulator and how facebow transfer relates the maxillary cast to the hinge axis
Your checkpoint
A 32-tooth morphologic worksheet with arch, quadrant, function, and distinguishing landmark for every tooth, filled in from memory
Anatomic Sciences & Biochemistry and Physiology & Microbiology and Pathology & Dental Anatomy and Occlusion
Complete two full-length timed practice exams under NBDE Part I conditions
Rank all four domains by accuracy and convert each weak area into a review list
Re-drill every missed item from weeks 1 through 7 until each is answered correctly twice
Rehearse the top 50 high-yield facts across each domain using spaced retrieval
Your checkpoint
A final one-page error summary showing post-review accuracy above 80% in every domain
Milestones
Week 2: Score 75% or better on the first timed mixed set and show a complete head-and-neck anatomy sheet with no unlabeled structures
Week 4: Complete the 100-question cumulative midterm and hold a dated error log with a cause category for every missed item
Week 6: Answer 30 spot questions on microbiology and pathology at 80% or better without notes
Week 8: Achieve 80% or better on each full-length practice exam and on every domain breakdown within it