NBDE Part I study materials
NBDE Part I study resources

NBDE Part I study plan

NBDE Part I · Give each week a clear focus.

8 weeks · About 8 hours per week

Week 1

Anatomic Sciences

  • Label from memory the 12 cranial nerves, their foramina of exit, and their major branches

  • Trace the arterial supply and venous drainage of the head and neck on a blank outline

  • Recite origins, insertions, actions, and innervation for the muscles of mastication and facial expression

  • Describe the anatomy of the temporomandibular joint capsule, disc, and ligaments

  • Identify the bones of the skull, their sutures, and the fossae they form

Your checkpoint

A hand-drawn head-and-neck anatomy sheet with all cranial nerves, vessels, and masticatory muscles labeled at 100% self-checked accuracy

Week 2

Anatomic Sciences & Biochemistry and Physiology

  • Explain branchial arch derivatives: skeletal, muscular, and nerve components for arches 1 through 6

  • Describe the development of the face, palate, and tongue, and name the corresponding congenital defects

  • Define the structure and ionization behavior of the 20 standard amino acids at physiologic pH

  • Explain enzyme kinetics using Michaelis-Menten terms and distinguish competitive from noncompetitive inhibition

  • Summarize the anatomic organization of the spinal cord tracts and the autonomic divisions

Your checkpoint

A 40-question timed mixed set across Domains 1 and 2, scored at 75% or better with every miss rewritten as a corrected fact card

Week 3

Biochemistry and Physiology

  • Diagram glycolysis, the citric acid cycle, and oxidative phosphorylation with net ATP and key regulatory enzymes

  • Compare gluconeogenesis, glycogenolysis, and the pentose phosphate pathway by substrate, tissue, and hormonal control

  • Explain lipid and amino acid catabolism and where they feed into the central pathways

  • Describe the hormonal axes of the thyroid, adrenal cortex, pancreas, and gonads with negative feedback loops

Your checkpoint

A one-page metabolic map drawn from memory, then corrected against notes, with all rate-limiting enzymes marked

Week 4

Biochemistry and Physiology & Microbiology and Pathology

  • Summarize renal physiology: glomerular filtration, tubular reabsorption and secretion, and acid-base compensation

  • Describe cardiac cycle phases, pressure-volume relationships, and how cardiac output is regulated

  • Explain the physiology of nerve conduction, synaptic transmission, and muscle contraction at the sarcomere level

  • Classify the major bacterial groups by Gram stain, morphology, oxygen requirement, and key virulence factor

Your checkpoint

A 100-question cumulative midterm across Domains 1 through 3, completed under timing, with every error logged by cause (knowledge gap, misread, or guess)

Week 5

Microbiology and Pathology

  • Differentiate the major oral and dental plaque organisms by habitat, Gram reaction, and caries or periodontal role

  • Summarize the structure and replication cycles of the major viral families, including herpesviruses and hepatitis viruses

  • Explain innate and adaptive immunity, immunoglobulin classes, and complement pathways

  • Describe the mechanism of action and spectrum for the major antibiotic classes and the basis of resistance

Your checkpoint

A two-column comparison table of at least 25 organisms with their associated oral or systemic disease, written to closed-book accuracy

Week 6

Microbiology and Pathology & Anatomic Sciences

  • Sequence the events of acute inflammation, from vascular changes through leukocyte extravasation and resolution

  • Distinguish reversible from irreversible cell injury and describe the pathways of necrosis versus apoptosis

  • Classify caries, pulpitis, and periapical pathology by etiology, histologic findings, and clinical sequence

  • Differentiate benign from malignant neoplasms and name the routes and patterns of metastasis

  • Describe the gross and microscopic features of common oral mucosal lesions and odontogenic cysts and tumors

Your checkpoint

A written pathology decision tree covering the 15 highest-yield oral lesions, validated against course notes with zero factual contradictions

Week 7

Dental Anatomy and Occlusion

  • Draw and describe each anterior and posterior tooth from all five aspects, including pulp chamber and root canal anatomy

  • State the eruption and exfoliation sequence for both dentitions with approximate ages

  • Classify Angle's occlusion and identify the features of ideal occlusion in the permanent dentition

  • Describe mandibular movements of opening, protrusion, and lateral excursion with their condylar and dental relationships

  • Explain the functional components of an articulator and how facebow transfer relates the maxillary cast to the hinge axis

Your checkpoint

A 32-tooth morphologic worksheet with arch, quadrant, function, and distinguishing landmark for every tooth, filled in from memory

Week 8

Anatomic Sciences & Biochemistry and Physiology & Microbiology and Pathology & Dental Anatomy and Occlusion

  • Complete two full-length timed practice exams under NBDE Part I conditions

  • Rank all four domains by accuracy and convert each weak area into a review list

  • Re-drill every missed item from weeks 1 through 7 until each is answered correctly twice

  • Rehearse the top 50 high-yield facts across each domain using spaced retrieval

Your checkpoint

A final one-page error summary showing post-review accuracy above 80% in every domain

Milestones

Week 2: Score 75% or better on the first timed mixed set and show a complete head-and-neck anatomy sheet with no unlabeled structures

Week 4: Complete the 100-question cumulative midterm and hold a dated error log with a cause category for every missed item

Week 6: Answer 30 spot questions on microbiology and pathology at 80% or better without notes

Week 8: Achieve 80% or better on each full-length practice exam and on every domain breakdown within it