CPN CPE III study materials
CPN CPE III study resources

CPN CPE III: Neonatal and Infant Care

CPN CPE III · Work through your exam, one topic at a time.

All guide sections

Neonatal and Infant Care

Neonatal items test the first hours and weeks: transition, screening, feeding, jaundice, and the complications of prematurity.

Delivery room and transition

  • APGAR at 1 and 5 minutes (Appearance, Pulse, Grimace, Activity, Respiration). It describes status; it does not drive resuscitation - begin resuscitation before the 1-minute score is assigned.
  • Dry, warm, stimulate; skin-to-skin and delayed cord clamping for stable term infants.
  • Thermoregulation: newborns lose heat by evaporation, conduction, convection, and radiation; dry immediately and place a hat.

Routine newborn care

  • Vitamin K 0.5–1 mg IM within 1 hour of birth.
  • Erythromycin 0.5% eye ointment within 1 hour to prevent gonococcal ophthalmia.
  • Hepatitis B vaccine within 24 hours; if the mother is HBsAg-positive, also HBIG within 12 hours.
  • Newborn screening heel stick at 24–48 hours, before discharge.

Common problems

  • Hypoglycemia: screen at-risk infants; treat <40 mg/dL in the first 4 hours with feeding or IV glucose.
  • Jaundice: plot bilirubin on the hour-specific nomogram; phototherapy above threshold. A rapidly rising level suggests hemolysis.
  • Breastfeeding: 8–12 feeds per 24 hours, at least 6 wet diapers per day by day 5.
  • Prematurity: surfactant for RDS, caffeine for apnea of prematurity, human milk fortification for growth.

Worked example

A 36-hour-old, 38-week, breastfed infant has a total bilirubin of 14 mg/dL. Age in hours and gestational age determine risk, not the raw number. Plot on the hour-specific nomogram; at 36 hours this is above the phototherapy threshold for a 38-week infant with risk factors - start phototherapy, continue breastfeeding, and recheck in 4–6 hours.

Traps

  • Using APGAR to decide whether to resuscitate.
  • Missing the timing of the repeat screening.
  • Reassuring a parent that “all newborns are jaundiced” without a bilirubin level.