OMSB Anesthesia (OEA) flashcards
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- MAC definition
- The minimum alveolar concentration of an inhaled anesthetic at 1 atmosphere that prevents movement in 50% of patients in response to a standard surgical stimulus.
- MAC-awake
- The alveolar concentration at which 50% of patients respond to verbal commands, approximately 0.3-0.4 MAC; it is used to estimate the threshold for awareness.
- Propofol induction dose
- 1.5-2.5 mg/kg IV in a healthy adult, with onset in 30-60 seconds and a duration of 5-10 minutes after a single bolus due to rapid redistribution.
- Succinylcholine dose
- 1-1.5 mg/kg IV, giving intubating conditions in 45-60 seconds and a duration of 5-10 minutes; it is metabolized by plasma pseudocholinesterase.
- Sugammadex dosing
- 2 mg/kg for train-of-four count 2, 4 mg/kg for post-tetanic count 1-2, and 16 mg/kg for immediate reversal after a large rocuronium dose.
- Neostigmine dose
- 0.03-0.07 mg/kg IV (maximum 5 mg) to reverse nondepolarizing blockade, given with glycopyrrolate 0.2 mg per 1 mg neostigmine to prevent bradycardia.
- Lidocaine maximum dose
- 4.5 mg/kg without epinephrine and 7 mg/kg with epinephrine; for a 70 kg adult this is about 315 mg plain or 490 mg with epinephrine.
- Dantrolene for malignant hyperthermia
- 2.5 mg/kg IV repeated until symptoms resolve, up to 10 mg/kg, combined with stopping triggers, 100% oxygen, cooling, and treatment of hyperkalemia.
- Cormack-Lehane grade III
- Only the epiglottis is visible during direct laryngoscopy, with no glottic structures seen; grades III and IV predict difficult intubation.
- Preoxygenation target
- Three minutes of 100% oxygen or four vital-capacity breaths achieves end-tidal oxygen above 90%, extending safe apnea time to 6-8 minutes in a healthy adult.
- Rapid sequence induction
- Pre-calculated induction dose plus a neuromuscular blocker without positive-pressure ventilation, with cricoid pressure, to reduce aspiration risk in full-stomach patients.
- Adult tube depth
- About 21 cm at the incisors in females and 23 cm in males, with the tip positioned 3-5 cm above the carina.
- Apfel PONV score
- Four predictors: female sex, non-smoker, history of PONV or motion sickness, and postoperative opioids; each adds about 20% risk.
- Spinal anesthesia level
- Injection into CSF at L3-L4 or below; hyperbaric bupivacaine 0.75% 1.5-3 mL gives onset within 2-5 minutes, with block height set by baricity and position.
- Epidural test dose
- 3 mL of lidocaine 1.5% with epinephrine 1:200,000, used to detect intravascular or intrathecal catheter placement before the main dose.
- Epidural blood patch
- 15-20 mL of autologous blood injected into the epidural space to treat persistent post-dural puncture headache after conservative measures fail.
- Lipid emulsion for LAST
- 20% lipid emulsion 1.5 mL/kg bolus followed by 0.25 mL/kg/min infusion for local anesthetic systemic toxicity, with airway and circulatory support.
- Oxygen content formula
- CaO2 = 1.34 × hemoglobin × SaO2 + 0.003 × PaO2, normally about 20 mL O2 per dL of blood.
- End-tidal CO2 normal
- 35-45 mmHg, typically 2-5 mmHg below arterial PaCO2; a sudden drop suggests disconnection, obstruction, or cardiac arrest.
- Lung-protective ventilation
- Tidal volume 4-6 mL/kg predicted body weight with plateau pressure ≤30 cmH2O in ARDS; this strategy reduces mortality.
- Fluid responsiveness
- Pulse pressure variation >13% or systolic pressure variation >10% in mechanically ventilated patients predicts a positive response to a fluid bolus.
- Fail-safe valve
- A device that stops nitrous oxide flow when oxygen pressure falls, preventing delivery of a hypoxic gas mixture.
- BIS target range
- A processed EEG value of 40-60 indicates adequate general anesthesia; values below 40 indicate deep anesthesia with hypotension risk.
- Defibrillation energy
- Biphasic 120-200 J and monophasic 360 J for ventricular fibrillation or pulseless ventricular tachycardia, with epinephrine 1 mg every 3-5 minutes.
- ASA physical status III
- A patient with severe systemic disease that is not incapacitating, such as poorly controlled diabetes, end-stage renal disease, or stable angina.
- Preoperative fasting times
- Two hours for clear liquids, four hours for breast milk, and six hours for a light meal or non-human milk before elective anesthesia.
- Revised Cardiac Risk Index
- Six predictors: ischemic heart disease, heart failure, cerebrovascular disease, insulin-dependent diabetes, creatinine >2 mg/dL, and high-risk surgery; ≥3 factors indicates elevated risk.
- Neuraxial anticoagulation timing
- Hold clopidogrel 5-7 days, warfarin until INR ≤1.4, and low-molecular-weight heparin 12 hours (prophylactic) or 24 hours (therapeutic) before neuraxial puncture.
- Pediatric uncuffed tube size
- Tube internal diameter in mm = (age in years / 4) + 4 for uncuffed tubes; subtract 0.5 mm for cuffed tubes.
- Holliday-Segar maintenance
- 4 mL/kg/h for the first 10 kg, 2 mL/kg/h for the next 10 kg, and 1 mL/kg/h for each kilogram above 20 kg.
- Left uterine displacement
- Displacing the uterus to the left after 20 weeks of gestation relieves aortocaval compression and improves venous return and cardiac output.
- Aldrete discharge score
- A score of at least 9 based on activity, respiration, circulation, consciousness, and oxygen saturation, used to determine readiness for PACU discharge.