PA-CAT study materials
PA-CAT study resources

PA-CAT study plan

PA-CAT · Give each week a clear focus.

8 weeks · About 6 hours per week

Week 1

Anatomy

  • Map all major body systems onto one annotated sheet, naming three signature organs and one clinical correlate per system.

  • Label the bones and landmarks of the axial and appendicular skeleton from memory on a blank outline within 15 minutes.

  • Trace blood flow through both cardiac circuits in order, naming every chamber, valve, and great vessel.

  • Build a 60-card spaced-repetition deck for anatomical position, planes, directional terms, and body cavities, and review it daily.

  • Sketch the brachial plexus and the major cranial nerves with their primary motor and sensory targets.

Your checkpoint

A closed-book labeling exam of 50 structures scored at or above 85%, with every missed item rewritten into the review deck.

Week 2

Physiology & Anatomy

  • Explain how each organ system preserves homeostasis using one named negative-feedback loop with sensor, integrator, and effector identified.

  • Compare cardiac, skeletal, and smooth muscle contraction, listing the ions, filaments, and regulatory proteins that differ.

  • Predict the direction blood pH, osmolarity, and glucose will shift when a named physiological variable is experimentally perturbed.

  • Diagram the nephron and the alveolar-capillary interface, labeling partial pressures and transport mechanisms at each step.

  • Re-test last week's 50 anatomical structures and re-learn every item missed twice.

Your checkpoint

A 10-item self-authored perturbation problem set answered at or above 80% with written physiological reasoning for each answer.

Week 3

Biochemistry

  • Draw glycolysis, the TCA cycle, and oxidative phosphorylation from memory, labeling enzymes, cofactors, and allosteric regulators.

  • Compute net ATP yield per glucose under aerobic and anaerobic conditions and justify every difference you calculate.

  • Classify the 20 amino acids by side-chain chemistry and predict where each would sit in a folded globular protein.

  • Apply Michaelis-Menten kinetics to predict how competitive, uncompetitive, and noncompetitive inhibitors shift Km and Vmax.

  • Explain how insulin and glucagon signaling oppose each other in fed and fasted states.

Your checkpoint

A one-page handwritten pathway map plus a 20-question metabolism quiz scored at or above 85%.

Week 4

Microbiology & Biology

  • Compare bacteria, archaea, viruses, fungi, and helminths on replication strategy, cell envelope, and druggable targets in a single table.

  • Rank the major antibiotic classes by mechanism of action and predict which resistance mechanism defeats each one.

  • Explain the phases of the bacterial growth curve and calculate generation time from a provided doubling dataset.

  • Describe innate versus adaptive immunity, naming the cell types, receptors, and signals that bridge the two.

  • Summarize viral replication cycles and identify where each major antiviral class interrupts them.

Your checkpoint

A 25-row pathogen-and-drug comparison table plus a 30-question microbiology and biology quiz scored at or above 80%.

Week 5

Genetics & Biology

  • Solve monohybrid, dihybrid, and sex-linked crosses and compute expected phenotypic ratios without consulting notes.

  • Interpret pedigrees to assign the mode of inheritance and identify obligate carriers.

  • Predict the protein-level consequence of missense, nonsense, frameshift, and splice-site mutations.

  • Calculate allele and genotype frequencies from population data and state which Hardy-Weinberg assumptions the data violate.

  • Describe cell-cycle checkpoints and explain how loss of each checkpoint contributes to oncogenesis.

Your checkpoint

Fifteen pedigree and calculation problems solved at or above 80% under a 25-minute timer with work shown.

Week 6

General Chemistry & Biochemistry

  • Solve stoichiometry, limiting-reagent, and titration problems to a stated accuracy standard without a formula sheet.

  • Calculate pH and pKa values and explain quantitatively how bicarbonate buffering holds blood pH within its narrow range.

  • Apply gas laws and Gibbs free energy relationships to predict spontaneity, equilibrium position, and temperature dependence.

  • Balance redox equations and identify the oxidizing agent, reducing agent, and electron count transferred.

  • Re-derive the three rate-limiting enzymes of glycolysis and explain how each is regulated allosterically and hormonally.

Your checkpoint

A 40-question timed general chemistry set scored at or above 80%, paired with a written error log categorizing every miss.

Week 7

Organic Chemistry

  • Identify functional groups and predict their reactivity toward nucleophiles, electrophiles, acids, and bases.

  • Draw arrow-pushing mechanisms for substitution, elimination, addition, and carbonyl addition-elimination reactions.

  • Distinguish SN1, SN2, E1, and E2 outcomes by substrate, solvent, base strength, and temperature, and assign R/S and E/Z stereochemistry.

  • Interpret IR and proton NMR spectra to propose a structure for an unknown compound.

  • Explain how resonance and inductive effects control acidity and reaction regioselectivity.

Your checkpoint

Ten spectra-to-structure identifications plus 20 mechanism questions scored at or above 80% in one sitting.

Week 8

Behavioral Sciences

  • Apply classical and operant conditioning, observational learning, and memory models to short clinical vignettes.

  • Explain health-behavior and adherence frameworks, including the role of provider-patient communication and health literacy.

  • Distinguish defense mechanisms, personality styles, and common psychiatric presentations and match each to a management principle.

  • Complete two full-length mixed practice exams under timed conditions and convert every error into a tagged review card.

  • Consolidate the 20 weakest facts across all domains onto a single final review sheet and recite them from memory.

Your checkpoint

Two full-length practice exams with a written error analysis and a final one-page weakest-20-facts sheet.

Milestones

Week 2: Recall 40 randomly drawn anatomical structures and 10 physiological feedback loops cold, at or above 85%, or re-allocate two hours from week 3 to anatomy review.

Week 4: Average at or above 80% across the week 1-4 quizzes and have all four domain deliverables complete; otherwise compress week 5 genetics goals to the three highest-yield ones.

Week 6: Score at or above 80% on a 50-question mixed set drawn from domains 1-7, and confirm no domain falls below 65% accuracy.

Week 8: Achieve at or above 75% on both full-length practice exams with no single domain below 65%, then spend the final two days only on the flagged weakest items.